Clinical trials: Body Weight Control
Pharmacology, Clinical
Study on the Safety of Neladenoson Bialanate, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Dug Given as a Single Oral Dose in Participants With Liver Impairment and Healthy Participants Matched for Age-, Gender-, and Weight
Neladenoson bialanate is currently under clinical development for a condition in which the heart has trouble pumping blood through the body (chronic heart failure).
- Trial name
- NCT04322253
- Testing
- Neladenoson bialanate (BAY 1067197)
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Bayer
Obesity or Overweight, Diabetes Mellitus, Type 2
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of AZD6234 will be compared to placebo in percent body weight change from baseline at 68 weeks of treatment
- Trial name
- SELENE 2 (NCT07784270)
- Testing
- Lenbelintide
- Where
- 230 sites in United States, Argentina and 14 more
- Volunteers
- 1,500 people
- Sponsor
- AstraZeneca
Overweight
Randomized Controlled Trial of Milk Products and Physical Activity on Body Composition and Health in Overweight Young Males
Maintaining a healthy body weight is a major challenge for the majority of Canadians. A lifestyle strategy that promotes maintenance of a healthy body weight and, perhaps most importantly, can be incorporated into daily life with…
- Trial name
- NCT01553370
- Testing
- Increased Dairy Intake, Supplemental carbohydrate
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Brock University
Overweight and Obesity
Effect of ANACA3 Slimming Gel on Loss of Abdominal and Thigh Circumferences in Healthy Volunteers
Overweight and obesity is defined, according to the World Health Organization (WHO), by abnormal or excessive accumulation of adipose or fatty tissue that may be harmful to health.
- Trial name
- NCT03685656
- Testing
- Slimming gel
- Where
- France
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Nutravalia
Obesity
Hybrid Argon Plasma Coagulation and Endoscopic Sleeve Gastroplasty Trial
This study is being done to evaluate the safety and effectiveness of combined Hybrid Argon Plasma Coagulation (HAPC) and Endoscopic Sleeve Gastroplasty (ESG) for weight loss and improvement in obesity-related co-morbidities…
- Trial name
- HAPCET (NCT05559866)
- Testing
- Apollo ESG with ERBE HAPC, Apollo ESG
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Mayo Clinic
Cachexia; Cancer, Non Small Cell Lung Cancer
A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) - 1
The goal of this clinical trial was to compare the efficacy and safety of anamorelin HCl (the investigational drug) to that of placebo (tablet with no drug) in patients with advanced non-small cell lung cancer and cachexia…
- Trial name
- NCT03743051
- Testing
- Anamorelin Hydrochloride
- Where
- 72 sites in United States, Bulgaria and 5 more
- Volunteers
- 318 people
- Sponsor
- Helsinn Healthcare SA
Obesity
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
This study will look at how well semaglutide helps children and teenagers losing weight. This will be tested by comparing the effect on body weight in children and teenagers taking semaglutide in comparison to placebo, a "dummy"…
- Trial name
- STEP Young (NCT05726227)
- Testing
- Semaglutide
- Where
- 56 sites in United States, Austria and 8 more
- Volunteers
- 212 people
- Sponsor
- Novo Nordisk A/S
Obesity
Catgut Implantation at Acupoints for the Treatment of Simple Obesity
The primary objective of this multicenter randomized controlled trial is to evaluate treatment effectiveness of intervening simple obesity people with catgut implantation at preferred acupoints, which excludes placebo effect; the…
- Trial name
- NCT02936973
- Testing
- Real catgut implantation at acupoints
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Hubei Hospital of Traditional Chinese Medicine
Cognitive Function and Mood, Cerebral Blood Flow
The Effects of Resveratrol Supplementation on Cognition, Cerebral Blood Flow, Microbiota and Systemic Inflammation.
Previous research shows that a diet high in fat has harmful effects on gut health. This increases the chance of developing obesity-related diseases (such as type 2 diabetes) and disrupts cognition and mood.
- Conditions
- Cognitive Function and Mood, Cerebral Blood Flow, Systemic Inflammation, Gut Microbiota
- Trial name
- NCT03448094
- Testing
- Resveratrol
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Overweight, Obesity
Motivational Interviewing for Overweight and Obese Adults at Healthy Life Centers
Overweight and obesity are major public health problems associated with increased morbidity and mortality. Motivational interviewing is a patient-centered counseling approach that may improve lifestyle behaviors and weight…
- Trial name
- MI-HLC (NCT07745231)
- Testing
- Motivational Interviewing, Routine Nutrition Counseling
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Sakarya University
Obesity
Dopamine Action on Metabolism in Relation to Genotype
Obesity is a widespread disease with increasing prevalence and associated with serious secondary complications. So far, the origin of the disease, regardless of an existing positive energy balance, is not fully understood.
- Trial name
- NCT03525002
- Testing
- Bromocriptine
- Where
- 3 sites in Germany
- Volunteers
- 120 people
- Sponsor
- University Hospital Tuebingen
Central Obesity
Electro-acupuncture for Central Obesity
In this study, a 8-week, single blinded, randomized controlled clinical trial will be conducted to examine the efficacy and safety of body acupuncture in the treatment of central obesity in Hong Kong.
- Trial name
- NCT03815253
- Testing
- acupuncture
- Where
- Hong Kong
- Volunteers
- 168 people
- Sponsor
- Hong Kong Baptist University
Overweight and Obesity, Healthy
A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants Receiving a Glucagon-like Peptide-1 (GLP-1) Agonist
Adult participants with BMI between 22 - 35 kg/m2 will be enrolled and randomized to receive either NG101 (20 mg twice daily [BID]) or placebo for 5 days beginning on Day 1.
- Trial name
- NCT06500429
- Testing
- NG101, Semaglutide Injectable Product
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Neurogastrx, Inc.
Obesity, Overweight or Obesity
A Phase 2b Study to Examine the Safety and Efficacy of Once-Weekly MET097 in Adults With Obesity or Overweight
This study is designed to test how well MET097, an active drug, works to treat individuals with obesity or overweight when compared to placebo. MET097 or placebo will be given to individuals weekly for 28 weeks.
- Trial name
- VESPER-1 (NCT06712836)
- Testing
- MET097
- Where
- 2 sites in United States
- Volunteers
- 239 people
- Sponsor
- Pfizer
Binge Eating Disorder, Obesity
Craving, Binge Eating and Obesity
This research study is designed to look at the effectiveness of bupropion for reducing binge eating in overweight persons with binge eating problems.
- Trial name
- NCT00414167
- Testing
- bupropion
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Yale University
Postmenopause, Overweight
Spirulina Supplementation in Postmenopausal Women
The purpose of this study is to investigate the effects of spirulina supplementation on weight gain associated with menopause, changes in metabolic parameters, sleep quality, and markers of depression in mildly overweight…
- Trial name
- NCT07718399
- Testing
- Spirulina
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Halic University
Food Cravings, rTMS
The Effectiveness of rTMS on Improving Food Craving and Weight Control in Adults Without Serious Mental Illness
Department of Psychiatry | Li Ka Shing Faculty of Medicine The University of Hong Kong The Effectiveness of rTMS on Improving Food Cravings and Weight Control in Adults without Serious Mental Illness Introduction The…
- Trial name
- NCT07106398
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Overweight and Obesity
Neurocognitive Benefits of a Weight Management Program
This study will assess whether weight loss induced through diet and physical activity can change neural responses to high- and low-calorie food images.
- Trial name
- NCT04202133
- Testing
- WW (formerly Weight Watchers), Waitlist
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Atherosclerotic Cardiovascular Disease, Overweight
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
The primary objective of this trial is to demonstrate that maridebart cafraglutide is superior to placebo when given as an adjunct to standard of care with respect to reducing cardiovascular (CV) morbidity and mortality.
- Conditions
- Atherosclerotic Cardiovascular Disease, Overweight, Obesity
- Trial name
- MARITIME-CV (NCT07037433)
- Testing
- Maridebart Cafraglutide
- Where
- 783 sites in United States, Argentina and 34 more
- Volunteers
- 12,800 people
- Sponsor
- Amgen
Metabolism and Nutrition Disorder, Obesity
Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects With Obesity
This trial is conducted globally. The aim of this trial is to investigate the effect of liraglutide for weight management in pubertal adolescent subjects with obesity.
- Trial name
- NCT02918279
- Testing
- Liraglutide
- Where
- 33 sites in United States, Belgium and 3 more
- Volunteers
- 251 people
- Sponsor
- Novo Nordisk A/S
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