Clinical trials: Body Weight Control
Obesity
One-anastomosis Gastric Bypass/Mini-Gastric Bypass Versus Roux-en Y Gastric Bypass
The aim of this prospective randomized controlled trial is to compare the two procedures One-anastomosis gastric Bypass/Mini-gastric Bypass (OAGB/MGB) and Roux-en Y gastric bypass (RYGB) in relation to intraoperative and…
- Trial name
- MGBvsRYGB (NCT03045679)
- Testing
- RYGB, OAGB/MGB
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sana Klinikum Offenbach
Preeclampsia, Gestational Hypertension
Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia
Preeclampsia causes devastating maternal and neonatal morbidity and mortality with a high recurrence risk and a rapid, occult progression to cardiovascular disease after delivery.
- Conditions
- Preeclampsia, Gestational Hypertension, Hypertension, Obesity
- Trial name
- HH4NM (NCT03749746)
- Testing
- Home Blood Pressure Monitoring, Heart Health 4 New Moms, Usual care
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnancy, Obesity
Effect of Probiotics (Vivomixx®) on Weight, Microbiota and Glucose Tolerance in Obese Pregnant Women and Their Newborn
The purpose of the study is to investigate if the probiotics Vivomixx® can affect gestational weight gain, microbiota and pregnancy complications in pregnant obese women and birth weight body composition of their infants.
- Conditions
- Pregnancy, Obesity, Gestational Diabetes Mellitus
- Trial name
- POP (NCT02508844)
- Testing
- Vivomixx®
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Weight Gain
Efficacy of Lifestyle Interventions and Metformin for the Treatment of Antipsychotic-Induced Weight Gain
Lifestyle intervention and certain medications have been shown to be effective for antipsychotic-induced weight gain, but no controlled studies have compared psychological and pharmacological therapies.
- Trial name
- NCT00451399
- Testing
- metformin, lifestyle intervention
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Central South University
Overweight or Obesity
Soy Peptide, Conjugated Linoleic Acid, Overweight or Obese, Body Composition
Soybean peptides are a mixture of active peptides obtained from the hydrolysis of soybean protein, which have biological activities such as antioxidant, blood pressure lowering, anti-fatigue and lipid lowering, etc.
- Trial name
- NCT04728399
- Testing
- Experimental group, Control group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fangfang Zeng
Metabolism and Nutrition Disorder, Obesity
A Randomised, Double-blind, Placebo-controlled Trial to Assess Safety, Tolerability and Pharmacokinetics of Liraglutide in Obese Adolescent Subjects Aged 12 to 17 Years
This trial is conducted in Europe. The purpose of the trial is to assess safety, tolerability and pharmacokinetics (the exposure of the trial drug in the body) of liraglutide in obese adolescent subjects aged 12 to 17 years.
- Trial name
- NCT01789086
- Testing
- liraglutide
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Novo Nordisk A/S
Childhood Obesity
Group Sessions and Web-based Treatment Targeting Children With Obesity Age 5-12 Years and Their Families
The aim of this study is to assess the efficacy of group sessions and a web-based program for children with obesity age 5-12 years and their parents.
- Trial name
- Webcop (NCT04013230)
- Testing
- Usual care, Web-COP
- Where
- 3 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Umeå University
Pregnancy Complications, Weight Gain
Impact of a Nutritional Intervention Program for Weight Control During Pregnancy
This is a randomized clinical trial for evaluate the impact of a nutritional intervention in the weight control of pregnant women according to the nutritional status, and consequently, the reduction of pregnancy complications.
- Trial name
- NCT00634530
- Testing
- Dietary Advice
- Where
- Brazil
- Volunteers
- 318 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Cardiovascular Diseases, Heart Diseases
Work, Weight, and Wellness Program: The 3W Program
The purpose of this study is to increase physical activity, improve diet, and reduce obesity of hotel employees.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00123019
- Testing
- Exercise and diet, Diet, Weight Reducing, Level 1
- Where
- United States
- Volunteers
- 6,100 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Self-regulation, Appetitive Behavior
Food for Thought: Executive Functioning Around Eating Among Children
Scientific knowledge of the cognitive-developmental processes that serve to support children's appetite self-regulation are surprisingly limited.
- Conditions
- Self-regulation, Appetitive Behavior, Eating Behavior, Child Obesity
- Trial name
- NCT06108128
- Testing
- Executive functioning observational tasks
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Temple University
Obesity, Adolescent
Preoperative Use of Liraglutide Additionally to Common Dietological Measures as Opposed to Dietological Measures Alone
The aim of the study is to investigate the effects of preoperative Saxenda (liraglutide). There are two groups, one group receives Saxena in addition to dietary measures when first seeking the operation, one group only diet.
- Trial name
- NCT06865365
- Testing
- Liraglutide daily (0.6-3.0mg, highest tolerable dose) additional to dietological measures and lifestyle optimization suggestions, Dietologic measures and lifestyle optimization for weight loss
- Volunteers
- 72 people
- Sponsor
- Medical University of Vienna
Dyslipidemia, Obesity & Overweight
Time-Restricted Eating With or Without Energy Restriction in Dyslipidemic Women With Owerweight or Obesity
Background/Objectives: It is unclear whether the effects of time-restricted eating (TRE) on body composition and blood lipids are independent of energy restriction (ER), and whether combining the two confers additional benefit.
- Trial name
- NCT07871565
- Testing
- TRE, ER, TRE+ER
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Acibadem University
Obesity, Eating Disorders
Internet Weight Control for Bingeing Adolescents
The purpose of this study is to determine if an internet-based intervention designed to reduce binge eating and improve healthy weight regulation skills will result in reductions in binge eating and weight loss, or weight…
- Trial name
- NCT00125112
- Testing
- Internet-based intervention designed to reduce binge eating and improve healthy weight regulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Morbid Obesity
Effect of Boussignac CPAP Ventilation on PaO2 and PaO2/FiO2 Ratio in Morbidly Obese Patients Undergoing Bariatric Surgery
The purpose of this study is to determine if the application of Boussignac continuous positive airway pressure (CPAP) immediately after extubation improves PaO2 and PaO2/FiO2 ratio in morbidly obese patients undergoing gastric…
- Trial name
- NCT02297828
- Testing
- Boussignac CPAP, Venturi face mask
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Centro Hospitalar do Porto
Fatty Liver Disease
A Research Study of a Potential New Medicine (NNC4005-0001) for Liver Disease in Adult Participants With Increased Body Weight and Liver Fat
The purpose of this clinical study is to find out if NNC4005-0001 is well-tolerated and safe for people who have increased body weight and increased liver fat.
- Trial name
- NCT07214870
- Testing
- NNC4005-001
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes, Obesity
Changes in Incretins Response and Glycemic Control After Gastric Bypass Surgery in Type 2 Diabetic Patients Versus Healthy
The purpose of this study is to determine the early changes in gut hormonal, and other metabolites with known relations to the glycemic homeostasis.
- Trial name
- NCT01820273
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lund University
Metastatic Pancreatic Cancer
Anamorelin Study for Advanced Pancreatic Cancer
Multicenter, double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of anamorelin HCl. Approximately 100 subjects with advanced PDAC and cachexia will be randomized 1:1 to anamorelin HCl 100 mg or…
- Trial name
- NCT04844970
- Testing
- Anamorelin Hydrochloride
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lahey Clinic
Obesity, Eating Behaviour
The Effect of Neurofeedback on Eating Behaviour
Neuroimaging is becoming increasingly common to investigate the neural networks underlying eating behaviour and food preference in normal-weight and obese humans.
- Trial name
- NCT02148770
- Testing
- Neurofeedback
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Croup
Croup Dosing Study
Croup is a common childhood respiratory disease that often leads to frequent emergency department visits. It is a viral infection that causes cough, throat, and airway swelling, making breathing difficult.
- Trial name
- NCT06272383
- Testing
- 0.15 mg/kg dexamethasone
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gestational Diabetes, Weight Loss
Smartphone App to Restore Optimal Weight in Women With Recent Gestational Diabetes
Gestational diabetes (GDM) complicates about 20% of pregnancies in Singapore. These women are at high risk of developing type 2 diabetes years after pregnancy; seven times more likely than normal.
- Conditions
- Gestational Diabetes, Weight Loss, Diet Habit
- Trial name
- SPAROW (NCT03324737)
- Testing
- Interactive Smartphone App
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore
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