Clinical trials: Body Weight Control
Insulin Resistance, Obesity
A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes
The purpose of this study is to determine whether the investigational drug INCB013739 has an effect on systemic and adipose tissue 11-HSD1 activity in obese, insulin resistant subjects.
- Trial name
- NCT00398619
- Testing
- INCB13739
- Where
- 2 sites in United States
- Sponsor
- Incyte Corporation
NAFLD
Effects of Tomato Products in Children With NAFLD
CONTROLLED TRIAL ON THE EFFECT OF TOMATO PRODUCTS IN OBESE CHILDREN WITH NON ALCOHOLIC FATTY LIVER DISEASE Aim of the study To evaluate the effect of the addition of a daily dose of lycopene enriched tomato sauce on the progress…
- Trial name
- NCT03463967
- Testing
- Lycopene-enriched tomato juice, Energy-restricted diet
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Federico II University
Overweight and Obese Women
The Effects of Yoga Exercises in Overweight and Obese Women
Obesity has been defined by the World Health Organization (WHO) as an abnormal accumulation of fat in the body that negatively affects health and has been reported to be the most significant public health problem of the 21st…
- Trial name
- NCT06979830
- Testing
- yoga exercises
- Volunteers
- 50 people
- Sponsor
- Ondokuz Mayıs University
Gestational Weight Gain
Motivational Interviewing on Diet, Lifestyle and Gestational Weight Gain of Pregnant Women
It is widely recognized that nutrition, metabolism and physical activity during pregnancy play a central role in several aspects of the health and well-being of pregnant women and their offspring.
- Trial name
- GLOW (NCT07635628)
- Testing
- Motivational Interview (MI)
- Where
- Italy
- Volunteers
- 228 people
- Sponsor
- IRCCS Burlo Garofolo
Bronchiolitis
Weight-based Flow Rates for Children With Bronchiolitis on High-Flow Nasal Cannula: A Pilot Randomized Control Trial
This is a pilot study comparing a weight-based high-flow nasal cannula (HFNC) protocol with the current standard HFNC protocol for children <2yo admitted to South Shore Hospital with bronchiolitis.
- Trial name
- NCT03492307
- Testing
- Weight-Based Flow for High Flow Nasal Cannula (HFNC) (2L/kg/minute), Standard Flow for HFNC (Maximum 8L/minute)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Overweight or Obesity
A Study of BGM0504 Injection in Participants With Obesity or Overweight
This is a multicenter, randomized, double-blind, placebo-controlled phase III validation clinical study in Chinese adult non-diabetic overweight or obese Participants.
- Trial name
- NCT06704581
- Testing
- 5 mg BGM0504 injection, 10 mg BGM0504 injection administered subcutaneously (SC) once a week, 15 mg BGM0504 injection
- Where
- China
- Volunteers
- 652 people
- Sponsor
- BrightGene New Bio-Medical Technology(Wuxi) Co.Ltd.
Obesity, Overweight
Impact of Almond Supplementation on Body Composition in Overweight/Obese Minority Adults
The purpose of this study is to determine whether introducing almonds into the diet of overweight and obese Blacks and Hispanics improves body composition, decreases liver fat, and lowers cardiovascular disease profile.
- Conditions
- Obesity, Overweight, Fatty Liver, Metabolic Syndrome X
- Trial name
- NCT02347007
- Testing
- Almond, Cereal Bar
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Columbia University
Non-specific Chronic Low Back Pain, Central Sensitization
Exercise Interventions for Overweight Men With Chronic Low Back Pain
This randomized controlled trial aims to compare the effectiveness of motor control exercise, aerobic walking exercise, and muscle strengthening exercise in overweight male adults with non-specific chronic low back pain and…
- Trial name
- MAMS-CLBP (NCT07688564)
- Testing
- Motor Control Exercise, Aerobic Walking Exercise, Muscle Strengthening Exercise
- Where
- Saudi Arabia
- Volunteers
- 156 people
- Sponsor
- Universiti Sains Malaysia
Obesity or Overweight, Cardiovascular Disease
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Established Cardiovascular Disease
This study will evaluate the efficacy and safety of petrelintide compared with placebo, in conjunction with a reduced-calorie diet and increased physical activity, for weight management in participants living with overweight or…
- Trial name
- ZUPREME-5 (NCT07843472)
- Testing
- Petrelintide
- Where
- 3 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Hoffmann-La Roche
Knee Osteoarthritis, Obesity
A Study of Econoglutide Injection in Obese Participants With Knee Osteoarthritis (KOA)
The main purpose of the study is to evaluate the efficacy and safety of ecnoglutide injections versus placebo in obese participants with KOA.
- Trial name
- NCT07734311
- Testing
- Ecnoglutide Injection
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Anesthesia Induction
Oxygenation Procedure for Obese Patients During Intubation in the Operating Room
Obesity is a risk factor for difficult intubation, with an incidence of up to 15.5%, and difficult mask ventilation. Obesity also reduces the functional residual capacity (FRC) of the lungs, the main reservoir of oxygen during…
- Trial name
- POP-OVNI (NCT06914401)
- Testing
- NIV (Non Invasive Ventilation) and HFNO (High Flow Nasal Oxygen), NIV (Non Invasive Ventilation)
- Where
- 5 sites in France
- Volunteers
- 124 people
- Sponsor
- Clinique Pasteur
Obesity, Morbid, Pregnancy
3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient
This study will be a randomized control study, with the objective to evaluate epidural analgesia success rates between the two methods (Blind Approach versus Accuro Device).
- Conditions
- Obesity, Morbid, Pregnancy, Pain
- Trial name
- NCT03405311
- Testing
- Rivanna Accuro 3D Ultrasound Device, Palpation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity, Life Style
EYTO (European Youth Tackling Obesity): A Randomized Controlled Trial in Catalonia (Spain)
Our hypothesis is that healthy lifestyles improvement by an intervention designed according 8 social marketing Benchmark criteria, can reduce overweight or obesity implemented by adolescents on their colleges.
- Trial name
- EYTO-SPAIN (NCT02157402)
- Testing
- Social marketing activities and pop-up events to promote healthy lifestyles
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Obesity, Weight Loss
Video Conferencing and In-person Health Coaching on Weight Loss, Physical Activity, and Metabolic Control
The purpose of this study was to determine how 12 weeks of health coaching with individualized feedback and education in combination with mobile health devices (a digital wireless body weight scale and wireless activity tracker)…
- Conditions
- Obesity, Weight Loss, Telemedicine
- Trial name
- NCT03278951
- Testing
- Video Conferencing Group, In Person Group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Hypertension, Diabete Type 2
Pharmacists Interventions on Patients Diabetic, and Obese Patients in the UAE: Randomized Controlled Trials.
Hypertension, diabetes, and obesity are considered major risk factors for cardiovascular diseases and premature mortality worldwide. Furthermore, they have severe consequences on quality of life among patients.
- Conditions
- Hypertension, Diabete Type 2, Obesity, Pharmacist-Patient Relations
- Trial name
- NCT05488002
- Testing
- Pharmaceutical intervention
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Central Obesity
Electro-acupuncture for Central Obesity
In this study, a 8-week, single blinded, randomized controlled clinical trial will be conducted to examine the efficacy and safety of body acupuncture in the treatment of central obesity in Hong Kong.
- Trial name
- NCT03815253
- Testing
- acupuncture
- Where
- Hong Kong
- Volunteers
- 168 people
- Sponsor
- Hong Kong Baptist University
Obesity
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PB-119 Injection in Chinese Obese Subjects
The trial is conducted in a single-center, randomized, double-blind, placebocontrolled, dose-increasing design. To evaluate the safety, tolerability, pharmacokinetics(PK) characteristics, efficacy and immunogenicity of PB-119…
- Trial name
- NCT06350812
- Testing
- PB-119
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PegBio Co., Ltd.
Obesity
A Trial To Study The Effects Of Group Versus Individual Dietary Counseling In Pediatric Obesity
Aim 1 - The primary aim of the study is to assess whether group counseling is a non-inferior intervention compared to the usual care of individual counseling in the management of childhood obesity.
- Trial name
- NCT01840631
- Testing
- Nutritional Counseling
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Albert Einstein College of Medicine
Thinness, Food Habits
Promotion of Egg and Eggshell Powder Consumption Improve Nutritional Status of Children in Halaba Ethiopia
Young children in Ethiopia lack sufficient protein and micronutrients for growth and development. The overall purpose is to assess the effects of promoting egg and eggshell powder consumption on improving the nutritional status…
- Conditions
- Thinness, Food Habits, Health Knowledge, Attitudes, Practices
- Trial name
- NCT02791100
- Testing
- Promotion of chicken eggs
- Where
- Ethiopia
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Type2 Diabetes, Obesity
The vBlocT2D Study
Overall aim: To demonstrate that weight loss through vBloc Therapy in combination with usual care will achieve better glycemic control for patients with obesity and type 2 diabetes than usual care alone.
- Trial name
- NCT03355092
- Testing
- vBloc Therapy
- Where
- United States
- Sponsor
- Kaiser Permanente
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