Clinical trials: Body Weight Control
Morbid Obesity
Extended Pouch Roux-en-Y Gastric Bypass Study
Morbid obesity is an increasing medical problem in the western countries. It's related to comorbidities as diabetes mellitus, hypertension, OSAS, arthrosis and hypercholesterolemia.
- Trial name
- NCT02218957
- Testing
- Extended Pouch RYGB, Standard RYGB
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Rijnstate Hospital
Overweight or Obesity
Effect of Akkermansia Muciniphila Akk11 on Metabolic and Gut Health in Overweight and Obese Subjects
To assess the efficacy and safety of the use of probiotics as a food supplement compared to placebo in regulating body metabolism and gut microbiota in overweight or obese subjects.
- Trial name
- NCT06653101
- Testing
- Probiotic
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Metabolic Surgery for Atrial Fibrillation Elimination
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is estimated that between 3 and 6 million Americans are currently living with AF, while 12 million people in the United States will have AF in 2030.
- Trial name
- METSAFE (NCT07027969)
- Testing
- Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ali Aminian
Weight Loss, Obesity
A Trial to Test an Acceptance-based Therapy Program Among Adolescent Girls With Overweight/Obesity
The purpose of this study is to investigate the effects of an acceptance-based therapy weight loss intervention compared with enhanced care for adolescents.
- Conditions
- Weight Loss, Obesity, Overweight
- Trial name
- NCT04484831
- Testing
- ABT Weight Loss Intervention, Enhanced Care
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Florida
Glycemic Control, Subjective Appetite
Sugars-sweetened Beverages and Exercise on Glycaemic Response and Subjective Appetite in Children
The purpose of the study is to understand the role chocolate milk compared to a fruit drink, with and without exercise, on glycaemic regulation and subjective appetite in children.
- Trial name
- NCT02197195
- Testing
- Chocolate Milk, Fruit Drink, Exercise
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Obesity and Diabetes Mellitus, Type 2
A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Severely Obese Participants With Type 2 Diabetes Mellitus
The purpose of this study is to assess the effects of JNJ-64565111 compared with placebo in severely obese Type 2 Diabetes Mellitus (T2DM) participants after 12 weeks of treatment on: the percentage change in body weight from…
- Trial name
- NCT03586830
- Testing
- JNJ-64565111 Dose Level 1, JNJ-64565111 Dose Level 2, JNJ-64565111 Dose Level 3
- Where
- 27 sites in United States
- Volunteers
- 196 people
- Sponsor
- Janssen Research & Development, LLC
Obesity
Targeting Obesity With the Probiotic Lactiplantibacillus Plantarum IMC 510 (PRO-Weight-Control Study)
In recent decades, the prevalence of obesity has reached epidemic proportions, with the number of overweight or obese individuals continuing to increase worldwide.
- Trial name
- NCT05358301
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Overweight, Diabetes
Effect of Gelesis200 on Body Weight in Overweight and Obese Subjects w/o Type 2 Diabetes
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis200 on Body Weight in Overweight and Obese Subjects without or with Type 2 Diabetes
- Conditions
- Overweight, Diabetes, PreDiabetes, Obesity
- Trial name
- LIGHT-UP (NCT03058029)
- Testing
- Gelesis200
- Where
- 30 sites in United States, Canada and 6 more
- Volunteers
- 300 people
- Sponsor
- Gelesis, Inc.
Obesity, Eating Behaviour
The Effect of Neurofeedback on Eating Behaviour
Neuroimaging is becoming increasingly common to investigate the neural networks underlying eating behaviour and food preference in normal-weight and obese humans.
- Trial name
- NCT02148770
- Testing
- Neurofeedback
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Asthma, Obesity
Can Diet- and Exercise-Induced Weight Loss Improve Asthma Control in Adults?
The goal of the study is to investigate the efficacy of an evidence-based weight loss intervention, on a background of quality health care, on asthma control among obese adults.
- Trial name
- NCT00901095
- Testing
- Lifestyle intervention
- Where
- 8 sites in United States
- Volunteers
- 330 people
- Sponsor
- Palo Alto Medical Foundation
Obesity, Prevention of Weight Gain
Evaluating a Small Change Approach to Preventing Long Term Weight Gain in Overweight and Obese Adults
Obesity is a major risk factor for disease and a public health problem. Recent information suggests that while it is possible for most overweight adults to lose a substantial amount of weight, maintaining the weight loss for any…
- Trial name
- NCT02027077
- Testing
- Control group, Lifestyle counselling
- Where
- Canada
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Queen's University
Overweight , Obesity
A Study of SRSD384 in Overweight or Obese Participants
This is a two-part study, intended to investigate the safety, tolerability, characteristics of PK and PD of single SC dose of SRSD384 alone in overweight or obese participants (Part A) and in combination with tirzepatide in…
- Trial name
- NCT07557355
- Testing
- SRSD384 injection
- Where
- Australia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Sirius Therapeutics Co., Ltd.
Childhood Obesity
Reducing Obesity Through Play Among Toddlers: Tiny Steps to Health (TSHS) Study
The purpose of this study is to test various ways to help toddlers develop healthy eating and activity behaviors. Parents and toddlers, who participate in this research will be randomly assigned to either 1) continue their…
- Trial name
- TSHS (NCT06918821)
- Testing
- Healthy Toddler Parent Group (HTPG), Families Understanding Nutrition and Physically Active Lifestyles (FUNPALs) Playgroup
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Houston
Aging
Greens-Based Crossover Trial to Improve Epigenetic Aging in Adults
The primary purpose of this study is to assess changes in epigenetic markers of aging and physiological parameters in overweight older adults consuming a mixed greens-based supplement over a 30-day period in a randomized…
- Trial name
- NCT06537232
- Testing
- Greens-based Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Auburn University
Recurrent Dislocation of Temporomandibular Joint (Disorder)
Evaluation of Using Patient Specific Ultra-High Molecular Weight Polyethylene Implant Versus Patient Specific Titanium Implant in Treatment of Chronic Condylar Dislocation A Randomized Control Trial
Does patient specific Ultra-High Molecular Weight Polyethylene implant eminoplasty will decrease maximum interincisal distance, provide better soft tissue response and post-operative patient satisfaction than patient specific…
- Trial name
- NCT07698678
- Testing
- Eminoplasty with patient specific ultrahigh molecular weight polyethylene onlay implant
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Obesity, Maternal, Pre-Eclampsia; Complicating Pregnancy
Nutrition Optimization and Community Upliftment for Postpartum Recovery: Hypertension
The goal of this clinical trial is to better understand how different strategies, timing, and enhancements to medically tailored food delivery will address structural inequities in the food environment, empower communities to…
- Conditions
- Obesity, Maternal, Pre-Eclampsia; Complicating Pregnancy, Gestational Hypertension, Eclampsia; Complicating Pregnancy
- Trial name
- NOURISH-HDP (NCT06445543)
- Testing
- MFeast ENHANCED, MFeast Usual Care
- Where
- United States
- Sponsor
- Johns Hopkins University
Chronic Management of Body Weight
A Clinical Study to Evaluate the Efficacy and Safety of HRS9531 Tablets in Overweight or Obese Subjects
This study aims to evaluate the efficacy and safety of HRS9531 tablets compared with placebo in reducing body weight in overweight or obese subjects after 52 weeks of treatment.
- Trial name
- NCT07670884
- Testing
- HRS9531 Tablet
- Where
- 2 sites in China
- Volunteers
- 675 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Family Health, Child Health
Healthy Children 2021 Study in Childcare Centers
In Portugal, 17.3% of children under 10 years old are overweight and 7.7% are obese. Research has shown the implementation of healthy lifestyle promotion programs and obesity prevention, however "best practices" are far from…
- Conditions
- Family Health, Child Health, Sleep, Child
- Trial name
- HC2021 (NCT04082247)
- Testing
- The education and training of early childhood educators and their intervention on children
- Where
- Portugal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Minho
Obesity, Superoxide Dismutase
Effect of 60-days Saccharomyces Boulardii and Superoxide Dismutase Supplementation in Obese Adults
In animals it has been demonstrated that Saccharomyces boulardii decrease low-grade inflammation and fat mass; also Superoxide Dismutase (SOD) decrease low-grade inflammation.
- Trial name
- NCT04919850
- Testing
- Saccharomyces boulardii and SOD
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Type 2 Diabetes, Obesity
The Effect of 3 Different Models of MNT on DM Control in Overweight Patients With T2DM
The American Diabetes Association (ADA), among other medical societies, is strongly recommending medical nutrition therapy (MNT) for prevention and management of type 2 diabetes.
- Trial name
- NCT02520050
- Testing
- Traditional MNT, Structured MNT, Structured MNT plus Weekly Support
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Joslin Diabetes Center
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