Clinical trials: Bone
Glomerular Disease, Bone Diseases, Metabolic
The Impact of Glomerular Disorders on Bone Quality and Strength
The primary objectives of this study are to: (1) determine the impact of glomerular disease on bone strength and (2) investigate the pathophysiologic underpinnings of impaired bone strength in glomerular disease.
- Conditions
- Glomerular Disease, Bone Diseases, Metabolic, Bone Fracture
- Trial name
- BoneGN (NCT04528446)
- Testing
- Dual-energy X-ray absorptiometry, High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT), Blood draw and Urine collection
- Where
- 2 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Columbia University
Osteopetrosis
Clinical Assessment of Patients With High Bone Mass Due to Mutation in Lrp5
The aim of the study is to describe patients with a high bone mass phenotype due to a mutation in the low density lipoprotein l receptor 5 gene (LRP5) and compare them with age and sex matched controls.
- Trial name
- NCT01199094
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Rotator Cuff Injuries
Demineralized Bone Matrix Rotator Cuff Study
Patients undergoing rotator cuff repair surgery will experience improved tendon healing with the use of demineralized bone matrix augmentation.
- Trial name
- NCT04686396
- Testing
- Demineralized bone matrix
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arthrex, Inc.
Complete Edentulism
Effect of Different Implant Surface Treatments on Bony Changes Around Mandibular Implants
The research will be conducted to report which type of surface treatment of dental implants that can be successful and aids in increasing bone to implant contact and how it affects the bony changes around the implants installed…
- Trial name
- NCT04686370
- Testing
- laser treated implant surface
- Where
- Egypt
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cairo University
Disc Herniation
The Effect of White Noise in Patients Undergoing Lumbar Disc Herniation Surgery
The aim of this clinical trial is to determine the effectiveness of listening to white noise on the sleep quality, comfort level, satisfaction level of patients after lumbar disc herniation surgery.
- Trial name
- NCT05687305
- Testing
- White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Buckle Fracture, Patient Satisfaction
Home Management of Pediatric Buckle Fractures
The goal of this clinical trial is to determine if a home management plan incorporating video education can effectively replace in-person visits for children aged 7-17 diagnosed with distal radius buckle fractures.
- Trial name
- HM-PBF (NCT06633094)
- Testing
- Educational videos
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Osgood-Schlatter Disease
Osgood-Schlatter Disease in Athletic Children
This study will be conducted to evaluate the effect of using Kinesio tape versus strapping the knee on pain management
- Trial name
- NCT06995794
- Testing
- kinesio tape, knee strap
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Family Genetic Characteristics of Osteoporosis
Family Cohort Study on Primary Osteoporosis
Bone metabolism and genetic characteristics of osteoporosis pedigree with kidney-yang deficiency
- Trial name
- NCT05781594
- Where
- 3 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Myelodysplastic Syndrome, Secondary Acute Myeloid Leukemia
Plasmatic L-AScorbic Acid in MYelodyplastic Syndroms and Controls
Myelodysplastic syndromes (MDS) is a group of heterogeneous diseases characterised by the clonal evolution of dysplastic hematopoietic stem cells.
- Trial name
- PLASMYC (NCT02809222)
- Testing
- Samples, Quality of life questionnaire
- Where
- 2 sites in France
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Osteoporosis
Effects of Jumping on Growing Bones
In this study we will investigate the effects of a high-impact exercise program involving jumping on bone mass (the amount of bone) of the hip and backbone in the growing skeleton.
- Trial name
- NCT00000405
- Testing
- Exercise intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Endosseous Dental Implant Failure, Bone Loss
Compare Sterilized Clean vs Sterilized Aseptic Dental Implant Surgery
In patients that require dental implants , does performing the surgery in clean sterile field compared to aseptic field, produces more post-operatory complications, implant morbidity or patient discomfort ?
- Trial name
- NCT01970826
- Testing
- Single Dental Implants, Sterilized Aseptic, Sterilized Clean
- Where
- Portugal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Acromegaly
Developing a Simple Recognition System of Acromegaly
We will compare the features of 3D stereophotography of acromegaly patients with that of healthy people. We hope to develop a computerized model to help screening acromegaly patients for early detection and treatment.
- Trial name
- NCT03042026
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Bone Tumor
Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of MW032 and Xgeva® in Healthy Adults
A randomized, double-blind and parallel group study to compare the pharmacokinetic, safety and pharmacodynamic of MW032 and Xgeva® in healthy adults.
- Trial name
- MW032 (NCT04798326)
- Testing
- MW032, Xgeva®
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mabwell (Shanghai) Bioscience Co., Ltd.
Mental Wellbeing, Depression, Anxiety
Effects of Vitamin D on the Behaviours, Mental, and Physical Health of Prisoners
This study aims to understand how vitamin D (VD) affects human health. Typically, prisoners are low on vitamin D, as it is difficult to receive through diet, and is mostly obtained via exposure to the sun.
- Conditions
- Mental Wellbeing, Depression, Anxiety, Bone Density, Low, Vitamin D Deficiency
- Trial name
- NCT05724316
- Testing
- Vitamin D supplement
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Atrophy
Effect of Whole Body Vibration on Bone and Fall Related Parameters
The effect of whole body vibration (WBV) on bone strength and fall frequency in older adults is still vague. Although there is some evidence that WBV may impact Bone Mineral Density in very frail elderly, there is a lack of data…
- Trial name
- NCT00292916
- Testing
- whole body vibration, resistance exercise, "wellness"
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Myelofibrosis
To Evaluate the Effect of Food on the Pharmacokinetics of TQ05105 Tablets in Healthy Adult Subjects
TQ05105 is a class 1 new drug with a new chemical structure developed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd. It is a Janus Kinase 2 （JAK2）inhibitor and can be used to treat JAK2 target-related diseases.
- Trial name
- NCT05982106
- Testing
- TQ05105 Tablets
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Stress Reaction, Stress, Psychological
Mind-Body Modalities for Nursing Students
Background: Nursing students around the world can experience tremendous stress due to their multi-faceted responsibilities. Stress is related to negative health and academic outcomes.
- Conditions
- Stress Reaction, Stress, Psychological, Stress, Physiological
- Trial name
- NCT05172804
- Testing
- Progressive muscle relaxation, Guided Imagery, Mindfulness Meditation
- Where
- Jordan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Osteopenia, Osteoporosis
Effects of Hesperidin on Bone Biomarkers in Postmenopausal Women
The primary objective of this clinical trial is to determine the effects of hesperidin on biochemical markers of bone in post-menopausal women.
- Trial name
- NCT00545116
- Testing
- Hesperidin
- Where
- Malaysia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Distal Humerus Fracture, Distal Femur Fracture
3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
The purpose of this study is to compare the effectiveness of 3D-printed bone models in addition to CT imaging versus CT imaging alone on surgical quality and operation time for patients undergoing surgical repair of…
- Conditions
- Distal Humerus Fracture, Distal Femur Fracture, Distal Tibia Fracture, Proximal Humeral Fracture
- Trial name
- SPRINT (NCT04748016)
- Testing
- 3D printed (3DP) bone models + CT imaging, CT imaging
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Acellular Dermal Matrix, Bone Grafting
Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix
This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.
- Conditions
- Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
- Trial name
- NCT07613047
- Testing
- Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham