Clinical trials: Bone Augmentation
Edentulous Alveolar Ridge
Long-term Follow up of Mucosal Tissue Height Influence on Peri-implant Bone Levels.
Our study looks into how the thickness of the gum tissue affects the health of the bone around dental implants over ten years. We include 59 people and divide them into three groups based on their gum tissue thickness.
- Trial name
- NCT06302322
- Testing
- Thin Tissues, Thick Tissues, Surgically augmented thin tissues
- Where
- Lithuania
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Missing Teeth
Lateral Ridge Augmentation Using Autogenous Bone Blocks or Xenogenic Bone Block Grafts Loaded With Recombinant Human Bone Morphogenic Protein 2
Since there are no clinical studies available comparing the gold standard (autogenous bone graft plus resorbable membrane) to the promising combination of xenogenic bone graft loaded with rhBMP-2 in combination with a collagen…
- Trial name
- NCT01541345
- Testing
- Autogenous bone graft, InductOs, Augmentation surgery
- Where
- 2 sites in Austria, Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Extented Platelet Rich Fibrin Block
Autogenous Bone Block Versus Extended Platelet Rich Fibrin Block for Horizontal Augmentation of Maxillary Ridge With Simultaneous Implant Placement
The aim of the study is directed to assess the clinical and radiographic outcomes of autogenous bone block versus extended PRF block used for horizontal augmentation of atrophied esthetic area of maxillary ridge associated with…
- Trial name
- NCT07424573
- Testing
- group I: autogenous bone block, extented platelet rich fibrin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Naira elnagar
Bone Involvement in Diseases Classified Elsewhere
Minimally Invasive Lateral Approach for Sinus Augmentation: a Split-mouth Randomized Clinical Trial.
It is assumed that the minimally invasive lateral approach and the traditional lateral sinus lift procedure will result in better outcomes in terms of height of augmented bone.
- Trial name
- NCT02117882
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Firenze and Siena, Napoli, Italy
Bone Augmentation, Bone Grafts
Filling Bone Defects/Voids With Autologous BonoFill-II for Maxillofacial Bone Regeneration
The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as a bone filler containing the patient's own (autologous) adipose (fat) tissue-derived cells in reconstructing bone in two clinical…
- Trial name
- NCT02842619
- Testing
- BonoFill-II
- Where
- Israel
- Volunteers
- 27 people
- Sponsor
- BonusBio Group Ltd
Horizontal Alveolar Bone Loss
Horizontal Ridge Augmentation Using Polyvinylidene Fluoride Versus Titanium Mesh Membranes
This study aims to evaluate the effectiveness of a new PVDF non-resorbable membrane versus Titanium Mesh in the treatment of horizontal ridge defects prepared for implant placement
- Trial name
- PVDF + HRA (NCT07095530)
- Testing
- titanium membrane
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Minia University
Posterior Mandible With Deficient Ridge Height
Vertical Ridge Augmentation With Autogenous Onlay Blocks Combined With Guided Bone Regeneration Versus Autogenous Bone Graft With Titanium Mesh in Posterior Mandible
Atrophic ridge augmentation utilizing guided bone regeneration (GBR) has become a major treatment option to provide optimal bone support for osseointegrated dental implants.
- Trial name
- NCT03680118
- Testing
- autogenous rings with GBR and autogenous graft with ti-mesh
- Volunteers
- 24 people
- Sponsor
- Cairo University
Alveolar Ridge Augmentation, Bone Grafting
Antibiotic Prophylaxis Versus Placebo in Alveolar Bone Grafting: A Randomized Controlled Trial
Tooth extraction sites often require alveolar bone grafting to preserve ridge dimensions and improve conditions for future implant placement.
- Conditions
- Alveolar Ridge Augmentation, Bone Grafting, Antibiotic Prophylaxis
- Trial name
- ABXGRAFT (NCT07296302)
- Testing
- Amoxicillin 500 mg (prophylactic regimen)
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Agnaldo Rocha de Souza Junior
Bone Regeneration
Teriparatide on Maxillary Sinus Floor Osseointegration
The aim of this triple blind randomized controlled trial will be to analyze the effect of a dose of teriparatide combined with a xenograft on bone augmentation of the maxillary sinus, to observe the microarchitecture of the newly…
- Trial name
- NCT06061354
- Testing
- Teriparatide, Maxillary Sinus Augmentation, Dental Implant Installation
- Where
- Chile
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Survival, Prosthesis, Bone Loss
Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Implant placement in the posterior part of the maxilla is frequently compromised or impossible due to atrophy of the alveolar process and pneumatisation of the maxillary sinus.
- Conditions
- Survival, Prosthesis, Bone Loss, Patient Satisfaction
- Trial name
- NCT04618900
- Testing
- Sinus floor elevation with a grafting material
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Horizontal Alveolar Ridge Deficiency
Autogenous and Xenograft Bone Mix in Alveolar Ridge Reconstruction
Following a tooth extraction, the loss of alveolar bone is inevitable. As the site remodels, the alveolar ridge naturally shrinks in both height and width (Schropp et al., 2003).
- Trial name
- NCT07883603
- Testing
- 25% Autogenous + 75% Xenograft, 50% Autogenous + 50% Xenograft
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- salah mohamed mohamed ibrahim ibrahim
Alveolar Bone Loss
Autologous Fat Grafting Versus Subepithelial Connective Tissue Graft for Volume Augmentation
The aim of this study was to evaluate the effectiveness of autologous fat as a grafting material for soft tissue volume augmentation of localized horizontal ridge defects in humans.
- Trial name
- NCT04214041
- Testing
- Autologous fat grafting, Sub-epithelial connective tissue graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Tooth Loss
The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation
The purpose of this study is to examine and compare the effects of autogenous dental pulp tissue on bone formation in the extraction sockets as compared to commonly used particulate bone graft.
- Trial name
- NCT03943849
- Testing
- Particulate bone graft, Autogenous dental pulp tissue, Resorbable collagen membrane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Alveolar Bone Grafting
E-Polycaprolactone-Containing Membrane in Alveolar Bone Regeneration
This study aimed to evaluate the effectiveness of synthetic polycaprolactone (PCL) bioscaffold membranes used for alveolar augmentation in maxillofacial surgery for increasing the amount of newly formed bone after…
- Trial name
- NCT06627621
- Testing
- Alveolar Ridge Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- cem üngör
Bone Regeneration, Bone Transplantation
Horizontal Ridge Augmentation With or Without Autogenous Block Grafts
To evaluate dimensional bone alterations following horizontal ridge augmentation using guided bone regeneration (GBR) with or without autogenous block graft (ABG) for the rehabilitation of atrophic jaws with dental implants.
- Conditions
- Bone Regeneration, Bone Transplantation, Bone Substitutes, Cone-beam Computed Tomography
- Trial name
- NCT03432702
- Testing
- Horizontal ridge augmentation
- Where
- Peru
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Científica del Sur
Osteoporosis
A Retrospective Comparison Between CPS and HC Techniques for Osteoporotic Fractures in the Thoracic or Lumbar Spine
Cement-augmented pedicle screws (CPS) and hybrid construct (HC) consisting of pedicle screws and additional hooks are common methods in osteoporotic fracture of the thoracic and lumbar spine.
- Trial name
- NCT05130242
- Testing
- Cement-augmented Pedicle Screws (CPS), Hybrid Construct (HC)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Alveolar Bone Resorption
Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips
The clinical cases in the present study described the khoury shell technique using an allograft plate and autogenous chips, for horizontal reconstruction of the anterior alveolar ridge in the esthetic zone.
- Trial name
- Shell grafting (NCT04324697)
- Testing
- Horizontal alveolar bone augmentation
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- October 6 University
Alveolar Bone Loss
Accuracy Assessment of Chin Graft for Ridge Augmentation Using Tooth-supported Guide Versus Free Hand Technique
This study compares the accuracy of osteotomies positions using patient specific guides for onlay bone shells harvested from the chin then the graft positioning for 3D upper anterior ridge augmentation using patient-specific…
- Trial name
- NCT07365852
- Testing
- 3D ridge augmentation using tooth-supported patient-specific guide
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Edentulous Jaw
Alloplastic Graft vs Xenograft for Horizontal Alveolar Ridge Augmentation
This prospective split-mouth randomized controlled trial compared horizontal alveolar ridge augmentation using alloplastic bone graft versus xenograft, both performed simultaneously with implant placement using the decompression…
- Trial name
- NCT07608744
- Testing
- Alloplastic bone graft, Xenograft
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ege University
Inadequate Bone Height in Maxillary Posterior Area
A Comparison of Bone Formation With Three Different Bone Graft Materials Following Sinus Graft
The purpose of this study is to compare new bone formation following bone graft in sinus using three different commercially available bone graft materials.
- Trial name
- NCT01911819
- Testing
- Sinus augmentation, Equimatrix, OSSIF-i sem
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Loma Linda University