Clinical trials: Bone Augmentation, open to volunteers
Peri-implant Bone and Soft Tissues
Sandwich vs. Mixed Bone Augmentation for Implant Placement
This study is being done to see which of two common grafting techniques-mixing two different grafting materials or layering two grafting materials-works better to augment bone volume next to participant's dental implant(s).
- Trial name
- NCT07832565
- Testing
- Sandwich bone augmentation, Mixed bone augmentation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Maxillary Sinus Augmentation
Radiographical, Histomorphometrical and Biomarker Analysis After Maxillary Sinus Augmentation Utilizing Xenograft Particulate Bone Graft Mixed With Parathyroid Hormone
This study aimed the to investigate the beneficial effect of combining PTH with bovine-derived bone graft bone in maxillary sinus augmentation.
- Trial name
- NCT07459075
- Testing
- Maxillary sinus augmentation
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- University of Baghdad
Transplant Failure or Rejection of Bone Marrow (Graft vs Host Disease, GVHD)
A Study of LBP-MARCO and Ruxolitinib in People With Graft-Versus-Host Disease (GVHD)
The researchers are doing this study to find out whether the combination of LBP-MARCO (Microbiota Augmentation to Reestablish Commensal Organisms) and ruxolitinib is a safe treatment for people with graft-versus-host disease…
- Trial name
- NCT07913672
- Testing
- Ruxolitinib, LBP- MARCO
- Where
- 7 sites in United States
- Volunteers
- 16 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Soft Tissue Augmentation Around Dental Implants
Vertical Soft Tissue Augmentation With Tent Pole Technique and Its Influence on Marginal Bone Loss Around Dental Implants
This study aims to evaluate the effectiveness of the tent pole technique in vertical peri-implant soft tissue augmentation and to assess its impact on marginal bone loss.
- Trial name
- NCT07018531
- Testing
- VST augmentation with TPT, TPT-PRF, TPT-PBM
- Where
- 2 sites in Spain, Tunisia
- Volunteers
- 112 people
- Sponsor
- University of Santiago de Compostela
Jaw, Edentulous, Partially, Diabetes
Maxillary Sinus Floor Augmentation in Diabetic Patients
Placement of implants in diabetic patients is associated with higher risk of implant failure and peri-implant marginal bone loss due to an increased susceptibility to infections, impaired wound healing and associated…
- Trial name
- NCT04543630
- Testing
- Sinus floor augmentation
- Where
- 3 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- University of Copenhagen
Bone Healing, Augmentation
Healing After Augmentation of Alveolar Ridge Using Collagen Membrane
One of the prerequisites for successful prosthetic implant therapy of patients is achieving the initial stability of the embedded implant, which largely depends on the width alveolar ridge, at the place of its installation.
- Conditions
- Bone Healing, Augmentation, Augmentation, Alveolar Ridge
- Trial name
- NCT06885983
- Testing
- implant placement, Guided bone regeneration
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Dental Implant
Hard Tissue Augmentation With or Without Connective Tissue Graft in Immediate Esthetic Implants
This randomized controlled study is aimed to evaluate the esthetic, clinical, and radiographic outcomes following the placement of immediate single-tooth implant with hard and soft tissue augmentation.
- Trial name
- NCT07333534
- Testing
- Immediate dental implant in the esthetic zone
- Where
- Iraq
- Volunteers
- 28 people
- Sponsor
- University of Baghdad
Bone Augmentation, Badly Broken Maxillary Premolars Indicated for Extraction
Comparison of Immediate Implant Placement With Titanium Mesh Versus Collagen Membrane in Type II Socket:
Statement of the problem: Immediate implant placement is faced with several problems. One of the most important issues is dealing with defects in the buccal plate of bone in the esthetic zone.
- Trial name
- NCT06875830
- Testing
- collagen membrane, titanium mesh
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Misr International University
Maxillary Sinus Floor Augmentation, Maxillary Sinus Elevation
Assessment of a New Enhanced Xenograft in Open Maxillary Sinus Augmentation
Implant supported dental restorations are sometimes challenging with decreased bone height in the posterior maxilla. The goal of this study is to test an augmentation bone substitute in elevating the maxillary sinus floor; in…
- Conditions
- Maxillary Sinus Floor Augmentation, Maxillary Sinus Elevation, Bone Augmentation
- Trial name
- sinus (NCT07737704)
- Testing
- Xenograft, maxillary sinus membrane elevation and stabilization.
- Where
- 3 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Misr International University
Maxillary Sinus Floor Augmentation
Osseodensification Versus Osteotome Internal Sinus Lifting in Delayed Implant Placement
The sinus lift technique through alveolar crest Osseodensification is conservative, minimally invasive, and minimally traumatic, utilizing hydropneumatic counterclockwise rotating instruments to lift the maxillary sinus floor…
- Trial name
- NCT05495490
- Testing
- Osseodensification Internal Sinus Lift, Osteotome Internal Sinus Lift
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Maxillary Deficiency, Horizontal Alveolar Bone Defect
Osseodensification Versus Alveolar Ridge Splitting
Evaluation of clinical and radiological outcomes of the alveolar ridge splitting technique versus Osseodensification burs in atrophic maxillary alveolar ridges in horizontal dimension.
- Trial name
- OD Vs ARS (NCT06728202)
- Testing
- A Horizontal Ridge Augmentation in Atrophic Maxillary Ridge
- Volunteers
- 46 people
- Sponsor
- Fayoum University
Alveolar Ridge Deficiency, Alveolar Bone Loss
Novel Synthetic Membrane for Horizontal Bone Augmentation: A Case Series
The goal of this clinical study is to learn if the Inox Nanoksa G-Plus membrane works to rebuild bone in the upper or lower jaw (ridge augmentation) for adults who need dental implants but do not have enough bone width or height.
- Trial name
- NCT07701473
- Testing
- Inox Nanoksa G-Plus Membrane, Particulate Bone Graft
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Posterior Mandible
Khoury's Bone Shell Technique Versus Titanium-Reinforced Polytetrafluoroethylene for Augmentation of Horizontal Deficiency in Posterior Mandible (Histomorphometry Analysis)
The purpose of the study is the comparison of bone gained histologically from the Bone Shell Khoury's Technique in comparison with the usage of non-resorbable membrane polytetrafluoroethylene and discussing its eligibility for…
- Trial name
- NCT07669792
- Testing
- GBR using Ti based PTFE, Bone Shell Khoury's Technique
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Vertebral Compression Fracture
A Clinical Study Evaluating the Safety and Efficacy of the VCFix Spinal System for Treatment of Vertebral Compression Fractures
This study is being conducted to evaluate the safety and performance of the VCFix Spinal System, a medical device designed to treat certain types of spinal fractures called vertebral compression fractures (VCFs) in adults.
- Trial name
- EXPAND (NCT07301749)
- Testing
- VCFix Spinal System in stand-alone configuration
- Where
- 3 sites in France, Germany
- Volunteers
- 148 people
- Sponsor
- Amber Implants B.V.
Anterior Maxilla Alveolar Bone Deficiency
Conventional Flap Versus Vestibular Flap in Bone Augmentation
two groups of patients both have alveolar bone deficiency in anterior maxilla, one group will be subjected to khoury bone augmentation with conventional flap the other with vestibular shifted flap
- Trial name
- (RCT) (NCT07664098)
- Testing
- vestibular shifted flap for bone augmentation, conventional flap
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Ridge Augmentation, Bone Grafting
Antibiotic Prophylaxis Versus Placebo in Alveolar Bone Grafting: A Randomized Controlled Trial
Tooth extraction sites often require alveolar bone grafting to preserve ridge dimensions and improve conditions for future implant placement.
- Conditions
- Alveolar Ridge Augmentation, Bone Grafting, Antibiotic Prophylaxis
- Trial name
- ABXGRAFT (NCT07296302)
- Testing
- Amoxicillin 500 mg (prophylactic regimen)
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Agnaldo Rocha de Souza Junior
Guided Bone Regeneration
Assessment Of Guided Bone Regeneration Using Xenograft Mixed With Allogenic Bone Graft Versus Xenograft Mixed With Autogenous Graft For Augmentation Of Maxillary Alveolar Ridges
This study aims to evaluate the effect of Allogenic bone graft mixed with Xenograft in ratio 1:1, on the radiographic and histomorphometric assessment versus Autologous bone graft mixed with Xenograft in ratio 1:1 in maxillary…
- Trial name
- NCT07367464
- Testing
- Allogenic bone graft mixed with Xenograft in ratio 1:1, Autologous bone graft mixed with Xenograft in ratio 1:1
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Ridge Deficiency
Custom-Made PEEK Versus PTFE Membranes in Maxillary Alveolar Ridge Augmentation
This randomized controlled clinical study aims to evaluate and compare the effectiveness of custom-made polyether ether ketone (PEEK) membranes versus polytetrafluoroethylene (PTFE) membranes in guided bone regeneration for…
- Trial name
- NCT07679451
- Testing
- Custom-made PEEK Membrane, PTFE Membrane
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Socket Preservation, Alveolar Ridge Augmentation
Comparative Analysis of 2 Bone Graft Materials in Socket Preservation
Socket preservation procedures after tooth extraction have been designed and implemented to maintain the volume of the bone and gingival tissues, which can decrease following the extraction of the teeth.
- Conditions
- Socket Preservation, Alveolar Ridge Augmentation, Dental Implants
- Trial name
- NCT07344025
- Testing
- Socket Preservation with Graft Material Allograft
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria