Clinical trials: Bone Changes
Dental Prosthesis Complication
Functional Relining Versus Digital Altered Cast Using Digitally Fabricated Distal Extension Frameworks
This clinical study will be done to compare between functional relining and digital altered cast of selective pressure impression techniques for constructing mandibular distal extension removable partial dentures using digitally…
- Trial name
- NCT06082609
- Testing
- Removable partial denture
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Edentulous Mandible
"Comparative Study of Supra-Structure Materials in Full-Arch Implant Prosthetics: a Randomized Clinical Trial"
after the implants' osseointegration period (4 months), digital scans will be taken for the implant positions and the STL files will be stored and sent for the CAD software to design a full arch restoration.
- Trial name
- CSDSMDA (NCT06673355)
- Testing
- dental implant prosthesis
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Phenylketonuria
Nutritional and Neurotransmitter Changes in PKU Subjects on BH4
HYPOTHESIS: The investigators hypothesize that KuvanTM therapy could influence nutritional and body composition parameters and neurotransmitter concentrations in pediatric and adult PKU subjects.
- Trial name
- BH4&PKU (NCT00688844)
- Testing
- KuvanTM Therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Emory University
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Axial Spondyloarthritis, Ankylosing Spondylitis
Is the Human Microbiome Altered in Patients With Axial Spondyloarthritis?
This study aims to compare biological communities in stool samples obtained from age, diet and BMI-matched subjects in five study groups: subjects with ankylosing spondylitis (AS) never treated with tumor necrosing factor (TNF)…
- Trial name
- NCT02962479
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eyal Kedar
Intervertebral Disc Herniation
MR Elastography for the Herniated Intervertebral Disc
Low back pain is a major cause of disability, especially in the working-age population. A total of 149 million working days are lost every year as a consequence of back pain.
- Trial name
- NCT03340545
- Testing
- Custom Magnetic Resonance Elastography Device
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Penn State University
Psychiatry
Comparison of Bone Mineral Density Changes During Tx With Risperidone or Aripiprazole in Adolescents
This study examines if the use of antipsychotic medications might contribute to an interruption in bone mineral development and/or a reduction in bone mineral content in adolescents.
- Trial name
- NCT00573716
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Creighton University
Osteoporosis
Changes of Bone Turnover Markers and Bone Mineral Density After Osteoporosis Treatment
To examine the changes of bone mineral density and bone turnover markers after Bonviva treatment in osteoporotic patients
- Trial name
- NCT02156999
- Testing
- Ibandronic acid, vitamin D
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Osteoporosis
Improving Bone Health in Adolescent Girls: The Youth Osteoporosis and Understanding Total Health (YOUTH) Study
Osteoporosis affects nearly half of all American women over age 50. During the teenage years, girls can increase bone growth to decrease their risk of osteoporosis later in life.
- Trial name
- NCT00067600
- Testing
- Diet with increased fruits, vegetables, and calcium, Increased high impact activity and resistance training
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Unspecified Disorder of Bone Density and Structure
Mg Induced Changes From Day 0 to Day 28 on Serum and Urine Bone Metabolic Parameters in 70 y Old Females (no 50).
Calcium and vitamin D substitution has for a long time been used to improve osteoporosis.The main storage place for magnesium is in the bone.
- Trial name
- parathormon (NCT02549521)
- Testing
- Oral magnesium substitution
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Weight Loss, Muscle Loss
Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency
Military personnel face many physiological challenges, including sustained physical activity and prolonged periods of negative energy balance.
- Conditions
- Weight Loss, Muscle Loss, Bone Loss
- Trial name
- NCT01292395
- Testing
- Dietary Protein Intake
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Obesity, Osteoarthritis
Arthritis Pilot for Preserving Muscle While Losing Weight
The purpose of this research study is to see whether wearing a weighted vest during a period of active weight loss can decrease the loss of muscle and bone that occurs during weight loss.
- Trial name
- APPLE (NCT02239939)
- Testing
- Vest, Diet
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteopenia
A Comparison of Changes in Bone Density With the Same Bone-health Plan, But With Different Bone-health Supplements
A comparison of changes in bone density following the same bone-health plan, but with a different bone-health supplement.
- Trial name
- NCT01114685
- Testing
- AlgaeCal-1, AlgaeCal-2
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Pseudohypoparathyroidism Type 1A, Albright Hereditary Osteodystrophy
Energy Expenditure and Body Composition in Pseudohypoparathyroidism 1a
The investigators would like to learn more about the metabolic consequences of pseudohypoparathyroidism type 1a in children, adolescents and adults with this condition.
- Trial name
- NCT01398774
- Where
- United States
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Alveolar Bone Loss
Dimensional Changes in Alveolar Ridge Preservation
Objective: The objective is to evaluate the dimensional changes of soft tissue and alveolar ridge after extraction of posterior elements with different clinical protocols of alveolar preservation.
- Trial name
- NCT06081296
- Testing
- Control group, Mixed free gingival graft group, Bone+ mixed free gingival graft group
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Renato Casarin
Osteoporosis
The Change of Bone Markers After Low Dose Alendronate in Postmenopausal Women With Bone Loss
High bone turnover with the bone resorption exceeding bone formation is a major mechanism of postmenopausal osteoporosis. Therefore, inhibition of bone resorption is a rational approach for the prevention.
- Trial name
- NCT00460057
- Testing
- Alendronate
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Eulji University Hospital
Immediate Implant With Loading
Evaluation of the Dimensional Alveolar Bone Changes in Immediate Post Extraction Implant Placement
The aim of this study was to evaluate the dimensional alveolar bone changes in immediate post extraction implant placement with loading compared to immediate post extraction implant placement without loading in the maxillary…
- Trial name
- NCT06515509
- Testing
- immediate implant placement with or without loading
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Atrophy
Comparative (Short vs. Standard) Length Implants in Early Stability Patterns.
Early Stability of Short vs. Standard Dental Implants in the Posterior Mandible This study compares how well short dental implants (7mm) work compared to standard-length implants (11mm) when placed in the back part of the lower…
- Trial name
- NCT07162389
- Testing
- Shallow-Threaded Short Implant (SHI), Shallow-Threaded Standard Implant (SDI)
- Where
- Yemen
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health