Clinical trials: Bone Changes
Tooth Loss, Edentulism
Influence of Implant Insertion Depth on Peri-implant Bone Changes Around Short Implants
Dental implants are widely used to replace missing teeth and restore oral function and aesthetics. One of the key factors affecting the long-term success of dental implants is the stability of the bone surrounding the implant…
- Conditions
- Tooth Loss, Edentulism, Peri-implant Bone Loss
- Trial name
- NCT07468747
- Testing
- Subcrestal Dental Implant Placement, Crestal Dental Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Recession
Modified Connective Tissue Graft Wall With Wing Technique for Posterior Teeth
The investigators reported here the application of usage modified connective tissue graft wall technique for posterior teeth. The treatment outcomes suggested the efficacy of the used technique in treating recession defects…
- Trial name
- NCT03716752
- Testing
- Modified connective tissue graft wall with wing technique
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Evaluation of Bone Changes Around Implants in Patients Treated With All on Four
The Goal of the clinical trail is to evaluate the Bone height changes around two axially placed anterior implants and two distally inclined 30-degree angle posterior implants in comparison to two axially placed anterior implants…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, All on Four Technique, Dental Implant
- Trial name
- NCT06723678
- Testing
- Two distally inclined 45-degree angle posterior implants, Two distally inclined 30-degree angle posterior implants
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Osteoporosis
The Change of Bone Markers After Low Dose Alendronate in Postmenopausal Women With Bone Loss
High bone turnover with the bone resorption exceeding bone formation is a major mechanism of postmenopausal osteoporosis. Therefore, inhibition of bone resorption is a rational approach for the prevention.
- Trial name
- NCT00460057
- Testing
- Alendronate
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Eulji University Hospital
Osteoporosis
Biological Bone Markers and Hydrolyzed Collagen Supplement in Menopausal Healthy Women
Preliminary scientific studies, in both animals and humans suggest that oral consumption of hydrolyzed collagen acts on the bone remodeling process by stimulating the activity of osteoblasts responsible for bone formation while…
- Trial name
- NCT01293045
- Testing
- hydrolyzed collagen, wheat protein
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nealth Sarl
Myeloproliferative Neoplasm
Cardiac Changes in Myeloproliferative Neoplasms
Myeloproliferative neoplasms are heterogeneous group of clonal hematopoietic stem cell neoplasms with excessive proliferation of one or more of the erythroid, megakaryocytic, or myeloid lineages and relatively normal maturation…
- Trial name
- NCT03177928
- Testing
- Transthorathic echocardiogram
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Relate Tooth Alveolar Extraction Socket Anatomy to Alveolar Remodeling Rate
In patients that are going to be subjected to a tooth extraction in the anterior maxillary (from canine to canine) does the position of the intact alveolar socket related to maxillary basal bone interferes with the rate of…
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Bone Resorption
- Trial name
- NCT01963884
- Testing
- Tooth Extraction, Cone-Beam technology evaluation, Measure Alveolar Socket Remodeling
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Chronic Myeloid Leukemia
Dynamic Changes in the Levels of sCD62L and SPARC in Chronic Myeloid Leukemia Patients During Imatinib Treatment
This study aims to monitor the levels of soluble L-selectin (sCD62L) and secreted protein acidic rich in cysteine (SPARC) in chronic phase chronic myeloid leukemia (CP-CML) patients at baseline and after three and six months of…
- Trial name
- NCT05387330
- Testing
- ELISA kit
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Tanta University
Bone Alteration, Dietary Modification
Efficacy of a Once Daily Calcium and Vitamin D Fortified Food Product to Improve Bone Microarchitecture
The primary objective of this randomized, double-blind, placebo controlled trial is to determine the efficacy of a once per day calcium (1000mg) and vitamin D (1000IU) fortified food product on bone turnover markers, including…
- Trial name
- NCT02375503
- Testing
- Calcium/Vitamin D
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Patient Satisfaction, Bone Loss
Marginal Bone Changes of CAD/CAM Implant Supported Screw-retained and Screw-mented Metal Frameworks
compare CAD/CAM implant supported screw-retained metal frameworks based on actual versus screw-mented ones based on virtual implant position regarding marginal bone changes.
- Trial name
- NCT04722744
- Testing
- screwmented metal frameworks
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Haematological Malignancy, Acute Leukemia
Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation
Allogeneic haematopoietic stem cell transplantation (aHSCT) is the only curative treatment for many paediatric and young adult haematological pathologies (acute leukaemia, myelodysplastic syndromes haemoglobinopathies, bone…
- Conditions
- Haematological Malignancy, Acute Leukemia, Myelodysplastic Syndromes, Hemoglobinopathy in Children
- Trial name
- EVAADE (NCT05298930)
- Testing
- Physical activity program
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre Leon Berard
Bone and Bones, Osteoporosis Risk
Milk Protein and Bone Health in Postmenopausal Women
The process of bone remodeling exhibits pronounced diurnal pattern that is important for bone health. A balanced rate of bone resorption is required to maintain bone health, a balance that can be disturbed during the life-cycle…
- Conditions
- Bone and Bones, Osteoporosis Risk, Osteoporosis, Postmenopausal
- Trial name
- OSTEOMILK (NCT03701113)
- Testing
- Milk-based protein matrix (MBPM), Habitual dietary behaviour
- Where
- Ireland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Periodontal Diseases
Fractal Analysis Method in Periodontal Disease
In this study, the effects of periodontal disease on alveolar bone were investigated using fractal analysis method.
- Trial name
- NCT05639582
- Testing
- fractal analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Parkinson Disease, Bone Loss
Bone Mineral Density Changes Among Clinical Subtypes of Parkinson's Disease
The bone loss in Parkinson's disease (PD) emerges as a non-motor symptom with motor and non-motor outcomes, such as fracture and musculoskeletal pain.
- Trial name
- NCT03806517
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ordu University
Axial Spondyloarthritis, Ankylosing Spondylitis
Is the Human Microbiome Altered in Patients With Axial Spondyloarthritis?
This study aims to compare biological communities in stool samples obtained from age, diet and BMI-matched subjects in five study groups: subjects with ankylosing spondylitis (AS) never treated with tumor necrosing factor (TNF)…
- Trial name
- NCT02962479
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eyal Kedar
Osteopenia
A Comparison of Changes in Bone Density With the Same Bone-health Plan, But With Different Bone-health Supplements
A comparison of changes in bone density following the same bone-health plan, but with a different bone-health supplement.
- Trial name
- NCT01114685
- Testing
- AlgaeCal-1, AlgaeCal-2
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Complete Edentulism
Patient Satisfaction and Crestal Bone Changes Around One-piece Zirconia(Zr) and Titanium(Ti) in Implant-Retained Mandibular Overdenture
This interventional randomized clinical trial study is conducted to assess patient satisfaction and crestal bone changes around one-piece Zr and Ti Implants in mandibular implant-retained overdenture in completely edentulous male…
- Trial name
- (Zr) - (Ti) (NCT06643975)
- Testing
- One-piece zirconia dental implants, One-piece titanium dental implants
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Weight Loss, BMD
The Effect of Weight Loss on Bone in Men
The purpose of this study is to determine the effect of weight loss on bone health in men.
- Trial name
- NCT00472745
- Testing
- Weight Loss, Weight Maintenance
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Obesity, Osteoporosis
Milk Supplementation and Energy Balance.
The aim of the project is to determine if milk supplementation during a caloric restriction program facilitates the lost of weight, improves the appetite control and attenuates the decrease of bone mineral content in low-calcium…
- Trial name
- NCT00729170
- Testing
- Supplementation of milk (35% more calcium)
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Laval University
Edentulous, Alveolar Process Atrophy
Evaluation of Implant Stability Changes in Sites Prepared with Different Osseodensification Techniques: a Prospective Observational Clinical Study
The goal of this observational study is to compare, within a cohort of patients requiring rehabilitation in two different sites of the premolar area in the upper maxilla, the primary and secondary stability of implants placed in…
- Trial name
- NCT06679894
- Testing
- Implant site preparation with osteotomes and electrified mallet, Implant site preparation with osseodensification drills
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy