Clinical trials: Bone Changes
Greater Tuberosity Fractures
Modified Hook Wiring Technique for Greater Tuberosity Fractures, a Prospective Study
the purpose of this study is to assess functional and radiological outcome of open reduction and internal fixation of isolated displaced greater tuberosity fractures (more than 5mm displacement) in adults advocating modified hook…
- Trial name
- NCT05403879
- Testing
- fixation of greater tuberosity fractures
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Hearing Loss, Bone Anchored Hearing Aids
Attitude Change Of Hearing Health Professionals On Bone-Anchored Hearing Devices Over Time In a Developing Country
This study aims to examine shifts in attitudes about bone-anchored hearing instruments (BAHIs) among hearing health professionals over a period of time.
- Trial name
- NCT06215599
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 243 people
- Sponsor
- Pamukkale University
Disc Degeneration
Low-grade Infections of the Intervertebral Discs
The purpose of this prospective, observational study was to evaluate frequency and characteristics of low-grade infections of the intervertebral discs in an unselected real-life patient population undergoing surgery for…
- Trial name
- NCT04712487
- Testing
- Microbiological culture, viral PCR, histopathological analysis
- Where
- Austria
- Volunteers
- 392 people
- Sponsor
- Kepler University Hospital
Multiple Myeloma
Efficacy of Response-adapted Treatment in Patients With Multiple Myeloma Candidates for Bone Marrow Transplantation
To assess whether continued treatment to achieve negative Minimal Residual Disease and Imaging (MRDI(-)) improves therapeutic outcomes in patients with newly diagnosed Multiple Myeloma.
- Trial name
- NCT05697913
- Testing
- Continued treatment adapted to the response
- Volunteers
- 66 people
- Sponsor
- Hospital Galdakao-Usansolo
Periodontitis, Periodontal Diseases
Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects
This study is meant to assess clinically and radiographically the possible predictable results regarding the use of nanocrystalline hydroxyapatite bone graft substitute together with papilla preservation flap versus papilla…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket, Intrabony Periodontal Defect
- Trial name
- NCT03588507
- Testing
- PPF+NCHA bone graft substitute
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoporosis
Effect of THAI Traditional Massage on Bone Markers
The purpose of this study is to explore the skeletal effect of Thai traditional massage by examining the changes in biochemical markers of bone turnover immediately after the massage.
- Trial name
- NCT00730600
- Testing
- Thai Traditional massage
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Bone Marrow Changes
Detection of Bone Marrow Changes: Comparison of MRI and DECT
Prospective study where magnetic resonance imaging is compared to dual-energy computed tomography for the detection of bone marrow changes.
- Trial name
- NCT01211392
- Testing
- magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Bone and Bones, Osteoporosis Risk
Nutritional Supplement and Bone Health in Post-Menopausal Women
The process of bone remodeling exhibits pronounced diurnal pattern that is important for bone health. A balanced rate of bone resorption is required to maintain bone health, a balance that can be disturbed during the lifecycle to…
- Conditions
- Bone and Bones, Osteoporosis Risk, Osteoporosis, Postmenopausal
- Trial name
- MBPS (NCT03337971)
- Testing
- MBPM
- Where
- Ireland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Rheumatoid Arthritis
Evaluation by HR-pQCT of Bone Microarchitecture Changes in Patients With Rheumatoid Arthritis Under Anti-TNF Therapy.
Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease in adults and is characterized by chronic inflammation of the joints leading to their destruction, resulting in a major loss of function.
- Trial name
- NCT02526992
- Testing
- HR-pQCT
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spinal Cord Injuries
Muscle and Bone Changes After 6 Months of FES Cycling
The goal of this clinical trial is to assess the effectiveness of FES cycling in terms of changes morpho-functional characteristics of the leg muscles, training performance and bone trophism in 5 subjects with Spinal Cord Injury…
- Trial name
- FES-Bike (NCT06321172)
- Testing
- FES Bike
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- IRCCS Eugenio Medea
Intervertebral Disc Herniation, Stiffness; Spine
Cervical Changes by 4h of Hyper-buoyancy Flotation and Followed by 15 Mins 1g Re-loading
Study with the aim to see the effect on a space ground anaologue, Hyperbuoyancy Floatation (HBF) on cervical column.
- Trial name
- NCT05296200
- Testing
- Hyperbuoyancy Floatation
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Universidad Autonoma de Madrid
Orthodontic Patients Indicated for Upper First Premolar Extraction, Orthodontic Patients Indicated for Maxillary Canine Retraction
Root Resorption and Alveolar Bone Changes in the Maxillary Canine Retraction Using Ni Ti Closed-coil Springs Versus Elastomeric Chains (A Split -Mouth Cone Beam CT Study)
This study will be carried out to asses root resorption and alveolar bone changes in the maxillary canine retraction using NiTi closed-coil springs versus elastomeric chains with cone beam CT
- Trial name
- NCT07116954
- Testing
- Twenty-Two adult Patients who indicated for bilateral maxillary first premolar extraction will be randomly assigned into two equal group., Canin retraction with NiTi Closed-Coil Springs and elastomeric chains
- Volunteers
- 22 people
- Sponsor
- Al-Azhar University
Osteoarthritis, Hip
Periprosthetic Bone Mineral Density Changes After Implantation Of A Short Hip Stem Compared To A Straight Stem
The aim of this study is to evaluate periprosthetic bone mineral density (BMD) changes in the proximal femur after implantation of the Fitmore compared to the CLS stem.
- Trial name
- NCT03147131
- Testing
- Total Hip Arthroplasty
- Volunteers
- 126 people
- Sponsor
- University Hospital Ulm
Osteoporosis
CR9112792, a Follow-up of Study CR9108963
The purpose of this study is to determine whether bone mineral density has increased in a subgroup of postmenopausal osteoporotic women from study CR9108963, between 6 and 12 months following cessation of ronacaleret therapy.
- Trial name
- NCT00891553
- Testing
- DXA
- Where
- 3 sites in Denmark, Norway
- Volunteers
- 171 people
- Sponsor
- GlaxoSmithKline
Osteoporosis, Obesity
Breastfeeding and Exercise for Healthy Infants and Postpartum Moms Too!
Approximately 8 million American women suffer from osteoporosis, and one out of every two women over the age of 50 will have an osteoporotic-related fracture in their lifetime (42).
- Conditions
- Osteoporosis, Obesity, Weight Loss
- Trial name
- BEHIP (NCT00966381)
- Testing
- Exercise and weight loss intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Bone Loss
Effect of Block-out Spacer to Pick up Locator Attachments to Retain Overdenture: Peri-implant and Alveolar Bone Changes
This study was conducted to radiographically evaluate peri-implant and alveolar bone height changes of locator attachments used for three implant assisted mandibular complete overdenture using two different pick up protocols.
- Trial name
- NCT05843825
- Testing
- Surgical placement of dental implants, Overdenture supported by locator attachment system
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries Extending to Pulp, Dental Implant Failed
Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone Changes
This study is conducted A- To investigate that PRF loaded with osteopromotive pharmacological drug can be a great aid in implant rehabilitation, and whether it could be a replacement for the other high price bone graft materials…
- Trial name
- NCT06016218
- Testing
- Simvastatin
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Bone Loss
Prosthetic Modality and MBL
The present study will test the effect of different prosthetic modalities on conical and internal hex connection implants, assessing the radiographic MBL changes after one year.
- Trial name
- NCT07156110
- Testing
- Traditional prosthetic procedure, one abutment-one time
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Rheumatoid Arthritis (RA), Atopic Dermatitis (AD)
A Study of Oral Upadacitinib (RINVOQ) Tablets to Assess Adverse Events and Change in Disease Symptoms in Korean Participants With Moderate to Severe Active Rheumatoid Arthritis, Atopic Dermatitis, Ankylosing Spondylitis or Psoriatic Arthritis
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints characterized by the swelling of multiple joints and tenderness caused by progressive inflammatory synovitis, which leads to serious and debilitating diseases.
- Conditions
- Rheumatoid Arthritis (RA), Atopic Dermatitis (AD), Ankylosing Spondylitis (AS), Psoriatic Arthritis (PsA)
- Trial name
- NCT04541810
- Where
- 116 sites in South Korea
- Volunteers
- 2,369 people
- Sponsor
- AbbVie