Clinical trials: Bone Fractures
To Assess the Bone Healing in Fracture Mandible Defects
COMPARATIVE ANALYSIS OF INNOVATIVE BONE HEALING TECHNIQUES
the study intends to observe the outcome of interventions (concentrated growth factor with autograft and xenograft) used to expedite bone healing and adaptation with minimal side effects.
- Trial name
- NCT05480631
- Testing
- autograft, autograft with addition of concenterated growth factor, xenograft with concentrated growth factor
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Simulation Based Medical Education
Optimizing Simulation-Based Training in Orthopedics: Exploring Deliberate Flawed Performance for Dynamic Hip Screw Osteosynthesis
Proximal femoral fractures (PFF) are associated with increased mortality when surgical intervention is delayed, with evidence supporting osteosynthesis within 12 to 24 hours of admission to minimize risk.1, 2 Consequently…
- Trial name
- NCT06729372
- Testing
- Deliberate Flawed Performance, Error Avoidance Training
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Diabetes Mellitus, Type 1, Bone Fracture
Prevalence of Vertebral Fractures in Patients With Type 1 Diabetes
Background : Type 1 diabetes is associated with an increased risk of fractures. The mechanisms accounting for this bone fragility are not yet fully understood.
- Conditions
- Diabetes Mellitus, Type 1, Bone Fracture, Bone Health
- Trial name
- DenSiFy (NCT04064437)
- Testing
- Clinical tests, Biochemical tests, DXA scan
- Where
- 2 sites in Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Ankle Fracture
The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture
The use of prophylactic treatment with vitamin c may prevent complex regional pain syndrome (CRPS)
- Trial name
- CRPS (NCT01338129)
- Testing
- vitamin c
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Distal Radius Fractures
Comparative Study Between Cannulated Screws and K-wires in the Fixation of Distal Radius Fractures
This comparative study aims to evaluate the clinical and radiological outcomes of cannulated screw fixation versus K-wire fixation in the treatment of distal radius fractures.
- Trial name
- NCT07523386
- Testing
- Cannulated screw Fixation In Treatment Of Distal Radius
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sohag University
Proximal Third Tibial Shaft Fractures in Children
Results of Retrograde Titanium Elastic Nails for Fixation of Proximal Third Tibial Shaft Fractures in Children.
Pediatric tibial shaft fracture is the third most common pediatric long bone fracture after fracture of femur and forearm, representing 15% of all pediatric fractures.
- Trial name
- NCT06500325
- Testing
- retrograde titanium elastic nails for fixation of proximal third tibial shaft fractures in children
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Scaphoid Fracture, Scafoïd; Fracture
Diagnostics of Scaphoid Fractures With HRpQCT
The scaphoid bone is the most common fractured carpal bone. Scaphoid fractures represent 2-6% of all fractures and occur mainly in young, active patients aged 15 to 40.
- Trial name
- NCT03899025
- Testing
- CT
- Where
- Netherlands
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VieCuri Medical Centre
Transverse Fracture of Shaft of Tibia
Comparison of Interlock Nailing Versus Dynamic Compression Plating in Transverse Fractures of Tibia
Study aims to compare two treatment modalities for treatment of transverse fractures of tibia. One is Intramedullary interlocking nail and the other is dynamic compression plate.
- Trial name
- NCT04958564
- Testing
- DCP
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- District Headquarters Teaching Hospital Sahiwal
Osteoporosis, Fractures, Compression
Dynamic Magnetic Resonance (MR) Study in Evaluating the Vertebral Bone Marrow Perfusion and Its Related Research
The etiology and pathogenesis of osteoporosis has been extensively discussed. The relationship between bone blood circulation and the formation of bony trabeculae has been less understood.
- Trial name
- NCT00172224
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Laryngoscopy, Stress Response
Comparison of Stress Response Evoked by Conventional Versus Videolaryngoscope
Impact of using video laryngoscopy versus direct laryngoscopy technique in terms of improved hemodynamics post intubation and time taken for intubation.
- Conditions
- Laryngoscopy, Stress Response, Duration
- Trial name
- NCT07510542
- Testing
- Endotracheal Intubation through a Video Laryngoscope (VL), Endotracheal Intubation through a Direct Laryngoscope (DL)
- Where
- Pakistan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Osteoarthritis, Knee, Fractures, Ununited
Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System
Brief Summary This clinical study investigates the safety and effectiveness of combining advanced regenerative therapies with personalized surgical technology for patients with delayed fracture healing (non-unions), knee…
- Conditions
- Osteoarthritis, Knee, Fractures, Ununited, Arthroplasty, Replacement, Knee
- Trial name
- MTDMS (NCT07628010)
- Testing
- Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zaporizhzhiya State Medical University
Unstable Lisfranc Fracture-dislocations of the Midfoot
A Comparison of Stainless Steel and Bioabsorbable Screw Fixation of Lisfranc Foot Injuries
The Lisfranc ligaments are a group of ligaments that connect the bones of the middle portion of the foot to each other. The Lisfranc ligaments allow for a normal and stable range of motion and shape to the foot.
- Trial name
- Lisfranc (NCT00985023)
- Testing
- Steel screw fixation of Lisfranc fracture-dislocation., Absorbable screw fixation of Lisfranc fracture-dislocations.
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Fractures
Intramedullary Devices for the Treatment of Unstable Pertrochanteric Fractures
The purpose of this study is to assess the differences between two different types of devices for the treatment of unstable pertrochanteric hip fractures.
- Trial name
- NCT02074969
- Testing
- Gamma Nail 3, PFNA
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Fracture, Forearm
Treatment of Stable Both-Bone Midshaft Forearm Fractures in Children
We create a randomized clinical trial between the treatment with above elbow armcast alone and the treatment of above elbow in combination with a short arm cast for stable midshaft both-bone forearm fractures.
- Conditions
- Fracture, Forearm, Midshaft, Child
- Trial name
- NCT00398242
- Testing
- above or below elbow cast for the last 3 weeks of treatment
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colaris, Joost, M.D.
Stress Reaction, Behavior, Social
The Effects of Therapy Dogs on Child Biology and Behavior
The objective of this study is to apply a rigorous experimental design to test whether children's interactions with therapy dogs increase immediate prosocial behavior and reduce immediate biological response to stress.
- Trial name
- NCT03949569
- Testing
- Therapy Dog, Stuffed Toy Dog, 5 Minute Puppy Video
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Fibula Fracture
Weight Bearing for Fibular Fractures
It is common practice to restrict weight bearing after ankle fracture open reduction and internal fixation (ORIF) until week 6 postoperatively. However, controversy exists surrounding the optimal postoperative protocol.
- Trial name
- NCT04872296
- Testing
- Controlled Ankle Motion (CAM) boot, Physical Therapy
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Femur Neck Fracture, Arthroplasty Complications
Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA
After total hip arthroplasty using an 'Modular Dual Mobility' acetabular cup, which is effective in reducing the risk of dislocation, one of the serious complications occurring after total hip arthroplasty, the blood metal ion…
- Trial name
- NCT05181566
- Testing
- Total hip replacement arthroplasty using modular dual mobility cup, Total hip replacement arthroplasty using conventional acetabular cup
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Infarction, Stroke
Polymorphisms in the Vitamin D System and Health
Polymorphisms in the vitamin D system appear to affect the serum 25(OH)D levels. If so one would expect these polymorphisms to be associated with vitamin D related conditions and diseases, which will be tested in the present…
- Conditions
- Infarction, Stroke, Diabetes, Fracture
- Trial name
- NCT01395303
- Where
- Norway
- Volunteers
- 9,700 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Osteoporosis
Opportunistic Fragility Fracture Risk Estimates From Radiographs
The proposed study will predict a patients' risk of having osteoporosis by using a combination of the IBEX BH (Bone Health) software outputs and other clinical risk factors such as age, gender, medical history and lifestyle.
- Trial name
- OFFER2 (NCT06110442)
- Testing
- IbexBH Software
- Where
- United Kingdom
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Accidental Falls, Osteoporosis
Prevention of Falls and Its Consequences in Elderly People
Falls are an important risk factor for fragility fractures. Both are associated with the ageing process and as they rise also increase the risk of mortality, disability and dependency.
- Trial name
- PRECIOSA (NCT02617303)
- Testing
- OTAGO's exercises, COMMON PRACTICE
- Where
- 11 sites in Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina