Clinical trials: Bone Healing
Tooth Extraction
A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction
This study will be a randomized clinical trial involving a total of 24 subjects. The investigators propose to recruit subjects into 2 groups: 1) Extraction treated with xenograft bone substitute (BioOss Collagen®) + collagen…
- Trial name
- NCT02844569
- Testing
- Xenograft bone substitute, Collagen dressing, 3D-collagen matrix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Alveolar Bone Loss
Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft
The study is a 3-arm, parallel-design, randomized, prospective clinical trial.designed to examine histologic wound healing following ridge preservation using cortical bone allograft, cancellous bone allograft, or a combination of…
- Trial name
- NCT02275767
- Testing
- 50% cortical/50% cancellous FDBA, 100% cortical FDBA, 100% cancellous FDBA
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Apical Periodontitis
Bone Regenerative Techniques in Endodontic Microsurgery
The purpose of this randomized controlled clinical trial was to evaluate two dimensionally and 3-dimensionally the effect of resorbable collagen-based bone filling material on periapical healing following endodontic microsurgery…
- Trial name
- NCT04514991
- Testing
- Foundation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Partial Edentulism
Comparison of Two Different Membranes
The purpose of the study is to compare one material called "Mucograft" with another material called "Dynamatrix." These materials are used as a type of a barrier (made from pig material also known as porcine material) in a…
- Trial name
- NCT01808794
- Testing
- Mucograft, Dynamatrix
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Tufts University
Partial Edentulism
Effect of Implant Thread Design on Implant Stability Quotient (ISQ) in Early Healing Period
The purpose of this study is to determine whether implant thread design impacts bone remodeling and/or dental implant stability in the early healing period.
- Trial name
- NCT02701387
- Testing
- Megagen AnyRidge dental implant, Megagen EZ Plus dental implant
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Femur Neck Fracture
Second Study of the Effect of Teriparatide on Hip Fracture Healing
The purpose of this study is to see whether teriparatide, given for 6 months versus placebo, will improve the healing of hip (femoral neck) fractures that are repaired during surgery using certain types of orthopedic screws.
- Trial name
- NCT01473602
- Testing
- Teriparatide, Calcium supplementation, Vitamin D supplementation
- Where
- 75 sites in United States, Belgium and 12 more
- Volunteers
- 39 people
- Sponsor
- Eli Lilly and Company
Bone Loss
Evaluation of Using Different Screwed Abutment Height
A prospective randomized controlled clinical trial will be conducted. Study groups will be assigned as described above. The patients will be randomly divided into two groups in order to study the influence of prosthetic screw…
- Trial name
- NCT06017115
- Testing
- Dental implant placement with COVER SCREW (two surgeries in control group) or DEFINITIVE TRANSEPITHELIAL ABUTMENT (one surgery in test group)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Bunion
Ketorolac Effects on Post-operative Pain and Bone Healing
This will be a randomized double-blind placebo-controlled clinical trial that will accept all eligible consecutive patients undergoing elective Kalish bunionectomies.
- Trial name
- NCT01133639
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Beth Israel Deaconess Medical Center
Fracture
Optimal Vitamin D3 Supplementation Strategies for Acute Fracture Healing
The objective is to determine the effect of vitamin D3 supplementation on fracture healing at 3 months.
- Trial name
- Vita-Shock (NCT02786498)
- Testing
- Vitamin D3
- Where
- 2 sites in United States, Canada
- Volunteers
- 102 people
- Sponsor
- University of Maryland, Baltimore
Alveolar Bone Loss
Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials
The purpose of this pilot study is to conduct a interventional prospective clinical trial to evaluate the efficacy of three different xenografts for ridge preservation by comparing the quality of newly formed bone using…
- Trial name
- NCT03149172
- Testing
- Equimatrix®, Bio-Oss®, Endobon®
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tufts University
Spondyloarthritis, Enterocolitis
Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing
Studies with intestinally asymptomatic patients with spondyloarthritis showed that approximately 1/3 had visible ulcers in the colon by scopic examinations and 2/3 had changes detectable by microscopy.
- Trial name
- INTASAH (NCT01174186)
- Testing
- Adalimumab
- Where
- 4 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Regionshospitalet Silkeborg