Clinical trials: Bone Health
Bone Health, Osteoporosis
Mediterranean Diet and Progressive Resistance Training Effects on BMD and Bone Turnover in the Elderly
This randomized controlled trial was designed to investigate the effects of progressive resistance training (PRT) combined with a Mediterranean diet on bone mineral density (BMD) and bone turnover markers (BTMs) in older adults.
- Trial name
- MED-RES-BONE (NCT07584785)
- Testing
- Mediterranean Diet combined with Resistance Training
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Osteoporosis, Osteopenia
Melatonin-Micronutrients for Osteopenia Treatment Study
The investigators' long-term goal is to employ novel methods to improve bone formation and bone density in women (and men) with osteopenia or osteoporosis while also decreasing signs and symptoms of degenerative joint and disc…
- Trial name
- MOTS (NCT01870115)
- Testing
- Fiber Pill, Melatonin, Strontium citrate, Vitamins D3 and K2
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Lumbar Spine Surgery, Lumbar Disc Herniation
The Effect of Mobilization Protocol Assisted With Simulated Clinical Immersion Videos on Patients Undergoing Lumbar Spine Surgery
This study focused on examining the effect of mobilization protocol assisted with simulated clinical immersion videos on postoperative pain, fear of movement, mobility level and satisfaction in patients undergoing lumbar spine…
- Trial name
- NCT05462210
- Testing
- Mobilization Protocol Assisted with Simulated Clinical Immersion Videos
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Osteoporosis Risk
Prune Consumption and Bone Health in Young Women Using Hormonal Contraceptives
The primary objective of this study is to determine if 12 months of consuming 50 grams of dried plum daily will prevent bone loss or augment bone accrual of young adult oral contraceptive (OC) users.
- Trial name
- NCT04785131
- Testing
- Prune
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Osteoporosis, Health Behavior
Striving to be Strong: Self-management
The vast majority of people want to be healthy and often make a change to be healthier. Change that is begun is seldom maintained.
- Trial name
- S2BS (NCT03405103)
- Testing
- Striving, Boning-Up, Personal Choice
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Milwaukee
Sarcopenia, Muscle Atrophy
Vitamin D and Resistance Exercise Training; Effects on Musculoskeletal Health in Frail Older Men and Women
This study aims to determine whether vitamin D3 supplementation is any more effective in improving musculoskeletal function when combined with exercise training compared with exercise training alone.
- Conditions
- Sarcopenia, Muscle Atrophy, Osteoporosis
- Trial name
- EXVITD (NCT02467153)
- Testing
- RET, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Edentulous Mandible, Implant-Supported Overdentures
Mandibular Implant Overdenture With Bar vs OT Equator: A Randomized Controlled Trial
This clinical study will evaluate two types of attachment systems used to support lower dentures in patients who have lost all their lower teeth.
- Trial name
- NCT07121881
- Testing
- Bar Attachment, Bar with OT Equator Attachment
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hala Abdel salam Selim
Depression, Healthy
Bone Loss in Premenopausal Women With Depression
The purpose of this study is to determine whether women with major depression lose bone mass at a faster rate than women without depression.
- Conditions
- Depression, Healthy, Osteopenia, Osteoporosis
- Trial name
- NCT00006180
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Premature Ovarian Insufficiency
Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency
Background: Premature ovarian insufficiency (POI) is a condition in which women under the age of 40 years have absent or irregular menstrual cycles. POI can cause infertility, signs of menopause, osteoporosis, and other symptoms.
- Trial name
- NCT06851754
- Testing
- Progesterone, Estrogen Patch
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bone Health, Cognitive Health
Skeletal and Cognitive Effects of Nutrition From Eggs
This project is the first egg feeding randomized controlled trial (RCT) in children. The goal of this RCT is to determine if eating formulated whole egg products for 9 months improves bone health and cognitive function in…
- Trial name
- SCENE (NCT03739424)
- Testing
- Whole egg powder, Whole milk powder, Gelatin food product
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Soy Isoflavone Effect, Bone Density, Low
Effects of Soy Isoflavone on Bone Health Among Saudi Female Students Imam Abdulrahman Bin Faisal University.
Low bone mineral density (BMD) has recently increased among young women. Soy Isoflavone as a food supplement, has been found to have potent effect on bone health in postmenopausal women.
- Conditions
- Soy Isoflavone Effect, Bone Density, Low, Bone Density Increased
- Trial name
- NCT04547010
- Testing
- Soy Isoflavone supplement
- Where
- Saudi Arabia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Bone Loss, Arteriosclerosis
Beneficial Effects of Long Term Menaquinone-7
From all K-vitamins, menaquinone-7 (MK-7) has been identified now as the most effective cofactor for the carboxylation reaction of Gla-proteins such as osteocalcin (in bone) and matrix-Gla protein (in the arterial vessel wall).
- Trial name
- NCT00642551
- Testing
- menaquinone-7
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Soccer, Bone Density
Effect of the Interaction Between the Type of Artificial Turf and Boots Model of Bone Health in Children Soccer Players
The number of turf fields has experienced an important increase in public and private facilities during the last years. This artificial surface will be predominant in any soccer field in the next years.
- Conditions
- Soccer, Bone Density, Physical Fitness
- Trial name
- FUTBOMAS (NCT02399553)
- Testing
- Soccer boot intervention
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Osteoporosis, Cardiovascular Risk Factor
Effects of a 12-week Home-based Yoga on Bone and Cardiovascular Health
While effects of specific exercise interventions on bone and CVD in postmenopausal women have been demonstrated and evaluated, the effects of randomized controlled exercise interventions, particularly in middle-aged premenopausal…
- Trial name
- NCT04353700
- Testing
- Yoga group
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Lowell
Intellectual Disability
Physical Activity, Sports and Health in Adults With Intellectual Disabilities
Currently, there is a paucity of quality research within the field of health science with a focus on persons with intellectual disabilities, and especially how longer lasting periods of varied physical activity affects the target…
- Trial name
- NCT05336487
- Testing
- Physical activity
- Where
- Denmark
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Bone Remodeling, Vitamin D
Bone Turnover Markers and Vitamin D Survey Among Health Professionals in Taiwan
This study will provide the first national overview of BTM and vitamin D utilization among healthcare professionals in Taiwan. The findings are expected to inform educational strategies, optimize clinical implementation, and…
- Trial name
- NCT07387458
- Where
- Taiwan
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Aging
Fiber and Calcium Absorption in Older Men
Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for age-related bone loss in men.
- Trial name
- NCT06519877
- Testing
- Soluble corn fiber
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Adrenal Hyperplasia, Congenital
Role of the Protein Osteoprotegerin in the Bone Health of Women With Congenital Adrenal Hyperplasia
21-hydroxylase deficiency (21-OHD) is an inherited disorder that results from a mutation on the CYP21A2 gene. It affects the adrenal glands and is the most common cause of congenital adrenal hyperplasia (CAH).
- Trial name
- NCT00694525
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Office of Rare Diseases (ORD)
Scoliosis
HRQoL and Function of Adults Treated in Adolescence for Scoliosis With Physical Exercises
We attempt to investigate the influence of physiotherapy and physical activity education applied in adolescence on physical fitness, curve progression, pulmonary function, physical activity and quality of life in adulthood.
- Trial name
- NCT01384955
- Where
- Poland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education