Clinical trials: Bone Health
Osteoporosis, Arthroplasty Complications
Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty
The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty.
- Conditions
- Osteoporosis, Arthroplasty Complications, Fragility Fracture
- Trial name
- NCT05845021
- Testing
- Surgeon-Initiated Bone Health Referral Pathway
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sarcopenia, Osteopenia
Nutrient Support to Body Composition and Healthy Ageing
The focus is healthy ageing, i.e. delaying the deterioration in health status in older adults. Loss of lean tissue (skeletal muscle) mass, a process termed sarcopenia, or bone tissue mass, a process called osteopenia, is a…
- Trial name
- BCHA (NCT02529124)
- Testing
- CONTROL, PROTEIN, PHYSICAL ACTIVITY
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Phil Jakeman
Bone Health, Vascular Health
Biocomparison Study
The effects of two vitamin K-forms on carboxylation of the vitamin K-dependent proteins osteocalcin and matrix-gla protein will be compared after supplementing these vitamins in a nutritional dose range.
- Trial name
- NCT01638182
- Testing
- Vitamin K1-capsules, Vitamin K2-capsules
- Where
- Netherlands
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Bone Health in Perimenopausal Women
A 12-week Human Trial to Compare the Efficacy and Safety of Polycan on Bone Metabolism
Beta-glucans are polysaccharides consisting of glucose residue jointed by beta linkage. They are found at a high level in the cell wall of fungi, yeast, oat, barley, bacteria, as well as various mushroom.
- Trial name
- NCT01402115
- Testing
- Polycan
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Osteoporosis, Osteopenia
Effects of Jumping on Bone Health in Young Women
This study evaluates the longitudinal, dose-dependent effects of jumping on bone health in young women. The women will be divided into 9 groups of varying jump height and repetitions, with a tenth group serving as control.
- Trial name
- NCT03413540
- Testing
- Jump
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- California State University, San Marcos
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Premature Ovarian Insufficiency
Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency
Background: Premature ovarian insufficiency (POI) is a condition in which women under the age of 40 years have absent or irregular menstrual cycles. POI can cause infertility, signs of menopause, osteoporosis, and other symptoms.
- Trial name
- NCT06851754
- Testing
- Progesterone, Estrogen Patch
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Intellectual Disability
Physical Activity, Sports and Health in Adults With Intellectual Disabilities
Currently, there is a paucity of quality research within the field of health science with a focus on persons with intellectual disabilities, and especially how longer lasting periods of varied physical activity affects the target…
- Trial name
- NCT05336487
- Testing
- Physical activity
- Where
- Denmark
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
FIT FIRST for the Bones
This study aims to conduct a cluster RCT intervention study with adolescents in Denmark and investigate whether the FIT FIRST concept can improve young people's bone health.
- Trial name
- FIT FIRSTftB (NCT07659587)
- Testing
- FIT FIRST
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Osteoporosis
Skeletal Health of Klinefelter Patients
This study compared the bone health of KS patients who were actively monitored in our clinic by dual-energy X-ray absorptiometry (DXA) with that of a control group of healthy volunteers.
- Trial name
- NCT03704987
- Testing
- dual-energy X-ray absorptiometry
- Where
- Turkey (Türkiye)
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Chronic Pain, Spine Disease
An Observational Study of Integrated Chronic Pain Management in a Community Health Center
This was a prospective observational study with the primary objective of quantifying a change in pain scores after 6-12 months of two separate interventions within the study site (pain team and chiropractic team).
- Trial name
- NCT04490291
- Testing
- chronic pain team, chiropractic team
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 1, Bone Health
Impact of Glycemic Control on Skeletal Outcomes in Adults With Type 1 Diabetes
Background : Type 1 diabetes (T1D) is associated with an increased risk of fractures. The mechanisms accounting for this bone fragility are not yet fully understood.
- Conditions
- Diabetes Mellitus, Type 1, Bone Health, Bone Loss, Bone Diseases, Metabolic
- Trial name
- DenSiFy cohort (NCT06351176)
- Testing
- Clinical tests, Biochemical tests, DXA scan with TBS and VFA
- Where
- 2 sites in Canada
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Osteoporosis Risk
Education Program on Increasing Osteoporosis Awareness Given to Women Aged 18-49
Summary Purpose: To examine the effect of the education program to increase osteoporosis awareness given to women aged 18-49. The research is carry out as a randomized controlled experimental in a pretest-posttest design.
- Trial name
- NCT05881850
- Testing
- Education Program on Increasing Osteoporosis Awareness Given to Women Aged 18-49. The research is carry out as a randomized controlled experimental in a pretest-posttest design.
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ankara University
Osteoporosis Risk, Menopause
Rhythmic Estradiol and Bone Health
The goal of this randomized-controlled trial is to compare the effect of rhythmic estrogen treatment to continuous estrogen treatment on bone turnover in healthy postmenopausal women.
- Trial name
- REBEL (NCT05903820)
- Testing
- Estradiol patch, Progesterone
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Tooth Loss, Edentulism
Influence of Implant Insertion Depth on Peri-implant Bone Changes Around Short Implants
Dental implants are widely used to replace missing teeth and restore oral function and aesthetics. One of the key factors affecting the long-term success of dental implants is the stability of the bone surrounding the implant…
- Conditions
- Tooth Loss, Edentulism, Peri-implant Bone Loss
- Trial name
- NCT07468747
- Testing
- Subcrestal Dental Implant Placement, Crestal Dental Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Cystic Fibrosis
Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls.
- Trial name
- NCT06216704
- Testing
- Magnetic resonance relaxometry, Magnetic resonance spectroscopy, Blood Draw
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bone Loss, Arteriosclerosis
Beneficial Effects of Long Term Menaquinone-7
From all K-vitamins, menaquinone-7 (MK-7) has been identified now as the most effective cofactor for the carboxylation reaction of Gla-proteins such as osteocalcin (in bone) and matrix-Gla protein (in the arterial vessel wall).
- Trial name
- NCT00642551
- Testing
- menaquinone-7
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Inactive 30-50-year-old Men
Recreational Football for Young-to-middle-aged Inactive Men
The aim of this study was to examine the health and physical fitness effects of 12 weeks of recreational football in inactive 30-50-year-old men.
- Trial name
- NCT07804563
- Testing
- Experimental: Intervention group
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Musculoskeletal Diseases
Effects of Nurse-led Patient Pathways
Objectives: This quasi-experimental pre-post-study investigated the effect of newly developed Nurse-led Patient Pathways (NPP) designed to improve patients', and health care professionals' as well as institutional outcomes.
- Trial name
- NPP (NCT02543307)
- Testing
- Nurse-led Patient Pathways
- Where
- Switzerland
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Dental Implants, Aggressive Periodontitis
Impact of Periodontitis Grading on Peri-Implant Clinical and Bone Health: A 60-Month Prospective Study
This prospective cohort study evaluated the effect of periodontitis grading on peri-implant clinical and radiographic outcomes over a 60-month follow-up.
- Conditions
- Dental Implants, Aggressive Periodontitis, Chronic Periodontitis, Staging
- Trial name
- NCT07671456
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil