Clinical trials: Bone Injuries Joints
Femoral Neck Fractures, Prosthetic Infection
Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture
Rational for conducting the study: Periprosthetic joint infection (PJI) is the most feared complication following prosthetic replacement of the hip joint and is associated with increased mortality, morbidity and economic burden.
- Trial name
- DAICY (NCT05164081)
- Testing
- antibiotic loaded bone cement (gentamicin+clindamycin) COPAL G+C (Heraeus)., antibiotic loaded bone cement (gentamicin) Paladins R+G (Heraeus) or Refobacin (Biomet).
- Where
- Sweden
- Volunteers
- 7,000 people
- Sponsor
- Umeå University
Carpal Tunnel Syndrome, Psoriatic Arthritis
Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis
This study aimed to investigate median nerve hypervasculatitation in psoriatic arthritis (PsA) patients with CTS or without CTS by using SMI, then compare them with normal people.
- Trial name
- NCT05086029
- Testing
- Superb Microvascular Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Displaced Extra-articular Distal Radius Fractures
Volar Internal Plate Fixation vs. Plaster in Extra- Articular Distal Radial Fractures
BACKGROUND: Fractures of the distal radius are common and account for an estimated 17% of all fractures diagnosed. Two-thirds of these fractures are displaced and require reduction.
- Trial name
- VIPER (NCT02030496)
- Testing
- open reduction and internal fixation, Closed reduction and plaster
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Post-traumatic; Arthrosis, Tibial Fractures
Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
High-energy tibial pilon fractures have historically been associated with poor outcomes largely due to the elevated risk of severe post-traumatic arthritis.
- Conditions
- Post-traumatic; Arthrosis, Tibial Fractures, Post-Traumatic Osteoarthritis of Ankle
- Trial name
- NCT05652881
- Testing
- Joint Lavage
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Spinal Fusion, Lumbar Fusion
Lumbar Fusion With Porous Versus Non-Porous Cages
The objective of this single site, randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo lumbar interbody fusion procedures (TLIF), supplemented with pedicle screw…
- Conditions
- Spinal Fusion, Lumbar Fusion, Arthrodesis, Spondylolisthesis
- Trial name
- NCT05583864
- Testing
- CONDUIT Porous Titanium Spinal Cage, PROTI 360 Titanium-Coated PEEK Spinal Cage
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Francis Farhadi
Osteoarthritis Elbow Left, Osteoarthritis Elbow Right
Elbow Arthroscopy Data Analysis
The purpose of this study is to evaluate preoperative objective measurements and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Conditions
- Osteoarthritis Elbow Left, Osteoarthritis Elbow Right, Lateral Epicondylitis, Left Elbow, Lateral Epicondylitis, Right Elbow
- Trial name
- EA (NCT03656185)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Femoral Neck Fracture, Infection
Early Periprosthetic Joint Infection and Outcome Debridement, Antibiotics and Implant Retention
Introduction Periprosthetic joint infection (PJI) is a severe complication to hip arthroplasty for femoral neck fractures (FNF).
- Trial name
- DAIR (NCT02771639)
- Testing
- Hip arthroplasty
- Volunteers
- 736 people
- Sponsor
- Sundsvall Hospital
Distal Radius Fractures, Lidocaine
Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures
To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties…
- Conditions
- Distal Radius Fractures, Lidocaine, Ropivacaine, Fracture Dislocation
- Trial name
- NCT06379490
- Testing
- Ropivacaine 0.2% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.5% Injectable Solution
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- Nordsjaellands Hospital
Patellofemoral Pain Syndrome
Dosage-dependence of Graded Exercise Therapy in Patients With Patellofemoral Pain Syndrome.
With this study two different therapeutic exercise regimens will be compared in patients with anterior knee pain (patellofemoral pain syndrome, PFPS).
- Trial name
- NCT01290705
- Testing
- High exercise therapy, Low exercise therapy
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Infection, Fracture
Metagenomic Next-Generation Sequencing for the Diagnosis of Fracture-related Infection
The value of next-generation sequencing (NGS) using Nanopore technology has been demonstrated in the case of diabetic patients' wounds or in prosthetic joint infections.
- Conditions
- Infection, Fracture, Bone
- Trial name
- METADIAG 2 (NCT07256405)
- Testing
- Metagenomic sequencing
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Tendon Injuries, Fracture
Question Prompt List for Orthopaedic Conditions
The purpose of this study is to investigate whether providing patients with a question prompt list (QPL) prior to their orthopaedic surgery clinic appointment improves their perceived involvement in care (PICs) score compared to…
- Conditions
- Tendon Injuries, Fracture, Arthritis, Sprains
- Trial name
- NCT03912168
- Testing
- Question Prompt List, 3 questions list
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Stanford University
Colles' Fracture, Radius Fractures
Operative Treatment of Extraarticular Colles' Fractures of the Distal Radius (OTEC)
This is a prospective, randomized, multi-center pilot study of unstable extraarticular fractures of the distal radius with dorsal displacement of the distal fragment in elderly patients.
- Trial name
- NCT00271726
- Testing
- Osteosynthesis with palmar locking plate, Osteosynthesis with external fixator, Osteosynthesis with Kirschner wires
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Osteoporosis, Osteoporosis Fracture
Breast Cancer Women on Aromatase Inhibitors Treatment
The main objective of the study is to improve the life quality of women treated with AI. Cohort B-ABLE is designed to evaluate musculoskeletal events derived of using AI in breast cancer women.
- Conditions
- Osteoporosis, Osteoporosis Fracture, Arthralgia Generalized
- Trial name
- B-ABLE (NCT03811509)
- Testing
- bisphosphonate
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Parc de Salut Mar
Hip Arthropathy, Hip Osteoarthritis
Post Market Clinical Follow-up of Dual-mobility Acetabular Cup EUROSCUP MOBILE
EUROSCUP MOBILE is intended for use in primary and revision total hip replacement surgery. Hip replacement is intended to provide increased patient mobility and reduce pain by replacing the damages hip joint articulation in…
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Arthritis, Hip Fractures
- Trial name
- NCT04993638
- Testing
- hip arthroplasty
- Where
- 3 sites in France
- Volunteers
- 147 people
- Sponsor
- EUROS
Osteoporosis, Rheumatoid Arthritis
Performance of CT Parameters Compared to Bone Mineral Density to Detect Bone Fragility in Rheumatoid Arthritis
Objective: To evaluate the performance of CT parameters (SBAC-L1 and fractal analysis) compared to BMD (gold standard) to detect vertebral fractures in rheumatoid arthritis
- Conditions
- Osteoporosis, Rheumatoid Arthritis, Vertebral Fracture
- Trial name
- NCT04413448
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Central Hospital, Nancy, France
Shoulder Impingement Syndrome, Adhesive Capsulitis
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM)
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM) is a limited lateral approach to the shoulder arthroscopically guided.
- Conditions
- Shoulder Impingement Syndrome, Adhesive Capsulitis, Rotator Cuff Tear, Hill-Sachs Lesion
- Trial name
- HLSSM (NCT05897866)
- Testing
- Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management
- Where
- Syria
- Volunteers
- 44 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.
Anterior Cruciate Ligament Rupture
Allogeneic Bone-patellar Tendon-bone Transplantation
Objective To investigate the mid-term clinical effect of bone-patellar tendon-bone (BPTB) graft double-bundle reconstruction of the anterior cruciate ligament (ACL) of the knee joint under arthroscope.
- Trial name
- NCT04951531
- Testing
- BPTB double-bundle allograft, BPTB single-bundle allograft group, BPTB single-bundle autograft group
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Peking University Third Hospital
Colles' Fracture, Distal Radius Fracture
Conservative Treatment of Distal Radius Fracture in Elderly in Randomized Controlled Trial
There is no consensus about the best conservative treatment for patients with dorsally displaced distal radius fractures. The previous studies that have examined the most valid method for cast immobilization have lacked uniform…
- Trial name
- NCT02894983
- Testing
- Flexion-ulnar cast, Functional cast
- Where
- 3 sites in Finland
- Volunteers
- 114 people
- Sponsor
- Tampere University Hospital