Clinical trials: Bone Injury
Femoral Neck Fractures, Periprosthetic Fractures
Postoperative Periprosthetic Fractures in Hip Fracture Patients: Exeter vs Anatomic SP2 Lubinus Stem
Recent studies have indicated a high incidence of postoperative periprosthetic femoral fracture in elderly patients treated with two commonly used cemented polished, tapered femoral stems.
- Trial name
- PPFEvL (NCT03326271)
- Testing
- Exeter stem, Lubinus SP2 stem
- Volunteers
- 2,527 people
- Sponsor
- Sundsvall Hospital
Femoral Fracture
Analgesia For Positioning Patient With Femur Fracture For Spinal Anaesthesia
This study is performed to determine the efficacy of ultrasound-guided fascia iliaca compartment block during positioning for spinal anaesthesia in patient undergoing repair of proximal femur fracture surgery comparing with…
- Trial name
- NCT02983344
- Testing
- Ropivacaine, Fentanyl, Ultrasound
- Where
- Malaysia
- Volunteers
- 24 people
- Sponsor
- Kuala Lumpur General Hospital
HIV Infections, Alcohol Drinking
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study
The purpose of this study is to follow a cohort of HIV-infected adults who have alcohol and/or drug use to: 1) test the associations between alcohol (and illicit drugs and polypharmacy (multiple prescribed medications)) and falls…
- Conditions
- HIV Infections, Alcohol Drinking, Substance-Related Disorders, Bone Diseases
- Trial name
- NCT03414411
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- Boston University
Femoral Neck Fractures
Vertical Femoral Neck Fractures in Young Adult Patients
Does the current techniques of internal fixation of vertical neck fracture in young adult patients give a satisfactory radiological and functional outcome at one year follow up?
- Trial name
- NCT04687592
- Testing
- reduction and fixation
- Volunteers
- 30 people
- Sponsor
- Assiut University
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Adhesions, Hand Fractures
Lipofilling in Operative Hand Fracture Treatment
Background: Hand fractures are a common clinical problem worldwide and account for a substantial economic burden and workload for experienced hand surgeons.
- Conditions
- Adhesions, Hand Fractures, Tenolysis
- Trial name
- NCT07815444
- Testing
- Lipofilling in Operative Treatment of Proximal Phalanx Fractures and Related Tenolysis
- Where
- Netherlands
- Volunteers
- 130 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Rib Fracture, Rib Fracture Multiple
Zimmer Biomet-RibFix Titan
Prospective, single-center, non-randomized, single-cohort, post-market clinical follow-up study to confirm the safety, performance, and clinical benefits for the use of the RibFix Titan™ system implants and instrumentation) in…
- Trial name
- NCT07485829
- Testing
- The RibFix Titan™ device should be used within this arm of the study.
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Zimmer Biomet
Ankle Fractures
WALANT and Spinal Anesthesia Comparison of Clinical Result in Ankle Fractures
The application of the WALANT technique for foot and ankle surgery (joint fusion, implant removal and tendon repair, etc.) is limited. In our study, using the WALANT technique for ARIF in ankle fractures.
- Trial name
- NCT06077344
- Testing
- WALANT in Ankle Fractures (Wide-Awake Local) Anesthesia No Tourniquet) and Applied Under Spinal Anesthesia Comparison of Clinical Results of Surgical Treatment;ANT Procedure comparation, Applied Under Spinal Anesthesia of Clinical Results of Surgical Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Blood Loss, Postoperative, Blood Loss, Surgical
EFFECT OF TRANEXAMIC ACID ON PERIOPERATIVE BLOOD LOSS IN REAMED INTRAMEDULLARY NAILING OF DIAPHYSEAL FEMORAL AND TIBIAL FRACTURES: A PROSPECTIVE COMPARATIVE STUDY
Perioperative blood loss is one of the most frequently encountered and significant complications of spine surgery. Intraoperative and post-operative bleeding cause various complications and negatively affect patient outcomes.
- Conditions
- Blood Loss, Postoperative, Blood Loss, Surgical, Femoral Fracture, Tibial Fracture
- Trial name
- NCT07625709
- Testing
- Intervention with Tranexamic Acid, Control group (Normal Saline)
- Where
- Nepal
- Volunteers
- 54 people
- Sponsor
- Kathmandu University School of Medical Sciences
Tibial Shaft Fracture
Study of Tibial Shaft Fracture Fixation: Intramedullary Nailing Comparing With Dynamic Compression Plate
The purpose of this study is to determine which surgical approach is better for treatment of tibial shaft fracture
- Trial name
- NCT01190709
- Testing
- Dynamic Compression Plate, Unreamed intramedullary nailing
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Osteoporosis, Secondary Hyperparathyroidism
Calcium and Vitamin D Malnutrition in Elderly Women
This study is designed to test whether calcium supplementation alone or calcium plus vitamin D reduces the incidence of fractures, reduces high parathyroid secretory activity, and halts bone loss in a population-based sample of…
- Trial name
- NCT00352170
- Testing
- calcium supplementation, calcium and vitamin D3 supplementation
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Creighton University
Tibial Fractures, Leg Injuries
Light Therapy in the Treatment of Leg Pain
The purpose of this study is to apply Anodyne therapy to active duty soldiers, who have shin splints, to evaluate healing time and effectiveness.
- Trial name
- MilCAM (NCT00253981)
- Testing
- Monochromatic Near-Infrared Light Energy (MIRE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Samueli Institute for Information Biology
Long Bone Nonunion
Use of Adult Bone Marrow Mononuclear Cells in Patients With Long Bone Nonunion
The aim of the study is to determine the safety and feasibility of autologous mononuclear stem cells in long bone nonunion; and moreover, to evaluate the efficacy of the treatment.
- Trial name
- NCT01581892
- Testing
- Osteosynthesis
- Where
- Spain
- Volunteers
- 7 people
- Sponsor
- Hospital Universitario Central de Asturias
Proximal Humeral Fracture
Perioperative Complications in Reversed Shoulder Arthroplasties
Retrospective observational study of reversed shoulder arthroplasties by proximal humeral fracture. Analysis of preoperative risk factors as well as minor and major complications at the first week, 90 days and 1 year.
- Trial name
- NCT03243409
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fracture Non Union, Infection
Antibiotic Loaded Calcium Sulfate RCT
This is a multi-centered, prospective, randomized controlled trial comparing current standard of care for defect management to placement of antibiotic loaded Stimulan as a bone void filler in patients undergoing treatment of…
- Trial name
- NCT03875963
- Testing
- Antibiotic loaded bone filler
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Femoral Fractures
A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
This study looks at two (2) types of surgical treatments and hopes to answer the question, "which is the best way to surgically treat a distal femur fracture?" Both procedures being studied are standard of care (used routinely)…
- Trial name
- NCT00429663
- Testing
- reamed, interlocking intramedullary nail, locking periarticular plate
- Where
- 22 sites in United States
- Volunteers
- 160 people
- Sponsor
- Boston Medical Center
Spinal Cord Injury
Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical…
- Trial name
- NCT07418398
- Testing
- Exoskeleton-Assisted Walking (EAW), Active Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Hip Fractures (ICD-10 72.01-72.2)
Mobility and Activity of Daily Living Outcomes After a Hip Fracture.
Hip fractures in especially older adults cause severe clinical and functional impacts. Despite improved surgical care, one year mortality remains 14-30%, and fewer than half of the survivors regain their pre-fracture functional…
- Trial name
- MOVE-HIP (NCT07556263)
- Where
- Netherlands
- Volunteers
- 1,200 people
- Sponsor
- JointResearch
Compartment Syndrome
Continuous Pressure Monitoring In Lower Leg Fractures
This study has been designed to allow us to learn more about diagnosing Compartment Syndrome, which is a condition that occurs in approximately 5% of tibial (lower leg) fractures.
- Trial name
- NCT00358514
- Testing
- Continuous Compartment Pressure Monitoring
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University of British Columbia
Osteoporosis, Management Care, Fracture
Optimization of Osteoporosis Management Among Patients Older Than 45 Years Old With Low Energy Fracture.
Harrington's metaphorical depiction captures the essence of the problem : "Osteoporosis care of fracture patients has been characterized as the Bermuda Triangle made up of orthopaedists, primary care physicians and osteoporosis…
- Trial name
- OPTIPOST (NCT02060747)
- Testing
- Coordinator-based post fracture program
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Fondation Hôpital Saint-Joseph
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