Clinical trials: Bone Marrow Biopsy
Pain, Acute, Anxiety
The Effect of Touch on Pain and Anxiety During the Bone Marrow Biopsy Procedure
This study is analyzing the benefit of untrained touch provided during a bone marrow biopsy procedure as compared to performing the procedure without providing it.
- Trial name
- Dixon Project (NCT04935775)
- Testing
- Untrained Touch
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Bone Marrow Biopsy
Protocol to Obtain Bone Marrow for Research
Potential donors who are undergoing bone marrow biopsy or bone marrow donation as part of clinical care will be asked by the principal investigator (PI) if they might be interested in donating marrow for this research project.
- Trial name
- NCT00951925
- Testing
- Bone Marrow Aspirate Draw
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colorectal Cancer (CRC), Specimens Are to be Collected From Subjects Who Are Having or Have Had a Fluid or Tissue Removed, a Biopsy or a Blood or Bone Marrow Draw
CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad
Collect some tumor tissue specimens from patients who have undergone colorectal cancer surgery and conduct experiments such as immunohistochemistry to observe the expression of related genes in colorectal cancer.
- Trial name
- NCT07197151
- Testing
- Perform surgery on patients with colorectal cancer and collect cancer and adjacent tissue specimens
- Where
- China
- Volunteers
- 32 people
- Sponsor
- hui hou
Bone Marrow Aspiration and Biopsy Specimen Collection
A Study Comparing Use of Manual and Power Bone Marrow Aspiration and Biopsy Devices in Children
The purpose of this study is to compare use of a powered bone marrow aspiration and biopsy device (OnControl) to use of a standard manual bone marrow aspiration and biopsy device to obtain bone marrow biopsy specimens in…
- Trial name
- NCT02159118
- Testing
- Manual bone marrow aspiration and biopsy device, Powered bone marrow aspiration and biopsy device
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Vidacare Corporation
Bone Marrow Biopsy
Comparison of a Powered Bone Marrow Biopsy Device With a Manual System
Bone marrow biopsy quality as quantified by biopsy cylinder length and diagnostic usefulness is improved with a powered bone marrow biopsy device in comparison with a manual device.
- Trial name
- NCT01535313
- Testing
- OnControl BM-Biopsy system
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Myeloid Leukemia
Refining the Role of Mid-induction Bone Marrow Biopsy in Acute Myeloid Leukemia: A Pilot Study
The purpose of the study is to observe the outcomes of patients with acute myeloid leukemia who do not receive an immediate second round of chemotherapy after undergoing a standard mid-induction bone marrow biopsy.
- Trial name
- NCT06323590
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Aromatherapy Oil Associated for Managing Anxiety and Pain During Bone Marrow Biopsy Procedures
This clinical trial evaluates whether using aromatherapy can reduce pain and anxiety for cancer patients during routine biopsy procedures.
- Trial name
- NCT06581211
- Testing
- Aromatherapy and Essential Oils, Electronic Health Record Review, Jojoba Oil
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- City of Hope Medical Center
Healthy Volunteers
Collection of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies
Background: Laboratory research studies require control samples from healthy volunteers to compare with samples from patients. These studies will help researchers better understand and refine treatments for immune system and…
- Trial name
- NCT00995891
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Neoplasms, Lymphomas
Collection of Tissue Samples for Cancer Research
Background: -Patients who are being evaluated and/or treated at the NIH Clinical Center and adult patients at participating sites will be entered onto this tissue procurement protocol for collection of tissue specimens.
- Conditions
- Neoplasms, Lymphomas, Multiple Myeloma, Myelodysplastic Syndrome
- Trial name
- NCT00900198
- Testing
- Biopsy
- Where
- 17 sites in United States, Canada
- Volunteers
- 5,000 people
- Sponsor
- National Cancer Institute (NCI)
Aplastic Anemia
Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A in Naive Aplastic Anemia (AA) Subjects
This was an open label, non-randomized, phase II study of eltrombopag in combination with rabbit ATG/CsA in subjects with moderate or more severe AA who did not received prior ATG/ALG-based immunosuppressive therapy.
- Trial name
- NCT02404025
- Testing
- Eltrombopag, Rabbit ATG, CsA
- Where
- 11 sites in Japan
- Volunteers
- 10 people
- Sponsor
- Novartis Pharmaceuticals
Bone Marrow
Prospective Bone Marrow Biopsy Safety and Efficacy Study
Bone marrow biopsy is a frequently performed procedure to diagnose and evaluate hematologic diseases. It is estimated that over 700,000 bone marrow procedures (BMP's) are performed annually in the U.S.
- Trial name
- NCT02524613
- Testing
- Pelvis CT scan
- Volunteers
- 50 people
- Sponsor
- Jacobi Medical Center
Ovarian Neoplasms, Ovarian Cancer
OveRcoming immunosupprEssion aNd rebAlancing the Immune reSponSe in ovAriaN CancEr Study
Ovarian cancer (OC) is one of the most lethal cancers in the world due to late-stage disease at diagnosis. Standard therapy consists of debulking surgery and chemotherapy.
- Conditions
- Ovarian Neoplasms, Ovarian Cancer, Ovarian Carcinoma, Immune Suppression
- Trial name
- RENAISSANCE (NCT06611072)
- Testing
- Bone marrow aspiration, Vena puncture, Peritoneal fluid
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gynaecologisch Oncologisch Centrum Zuid
Myeloproliferative Neoplasm
A New Blood Score for Myelofibrosis Staging
BCR:ABL1 negative myeloproliferative neoplasms (MPN) include three entities: polycythemia vera, essential thrombocythemia and primitive myelofibrosis.
- Trial name
- FIBROMOELLE (NCT06177366)
- Testing
- Blood sampling
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bone Marrow Disease, Hematological Malignancy
The Effect of Music Therapy on Comfort, Pain and Anxiety
Objectives: This study was conducted to determine the effect of music therapy on the pain, anxiety, and comfort levels of patients who underwent bone marrow aspiration and biopsy.
- Trial name
- NCT05895357
- Testing
- Musictherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Izmir Bakircay University
Lymphoma
PET/CT Vs Bone Marrow Biopsy in Exclusion of Bone Marrow Infiltration for Initial Staging of Lymphoma
lymphoma is a common malignancy in the developed world. the two main categories of lymphoma are non-Hodgkin lymphoma and non-Hodgkin lymphoma.
- Trial name
- NCT05565898
- Testing
- positron emission tomography for exclusion of bone marrow infiltration in lymphoma
- Volunteers
- 100 people
- Sponsor
- Assiut University
Myeloproliferative Neoplasm
Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in MPN Patients
The PERIBLOOD-MPN study aims to develop and validate a minimally invasive peripheral blood test using single-cell RNA sequencing to accurately diagnose and classify myeloproliferative neoplasms, potentially reducing the need for…
- Trial name
- NCT07648433
- Testing
- PERIBLOOD-MPN
- Volunteers
- 500 people
- Sponsor
- Weizmann Institute of Science
Bone Marrow Cancer, Leukemia
Improving Patient Experience: BMBA
This study seeks to determine if patients undergoing a bone marrow biopsy/aspiration (BMBA) procedure who receive distraction techniques have lower levels of distress and pain, and higher post-procedure satisfaction, compared to…
- Conditions
- Bone Marrow Cancer, Leukemia, Lymphoma, Multiple Myeloma
- Trial name
- NCT05690230
- Testing
- Virtual reality, Environmental changes
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Anxiety and Fear, Pain
Effect of Short Film Video Training Prepared for Children Undergoing Bone Marrow Aspiration and Biopsy
In this study, it is aimed to examine the effect of short film video education given to children aged 7-12 years who will undergo CIAB before the procedure on the anxiety, fear, pain and satisfaction levels of the children.
- Conditions
- Anxiety and Fear, Pain, Satisfaction
- Trial name
- NCT06698445
- Testing
- Short film video
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Tarsus University
Hematologic Diseases, Diagnoses Disease
Impact of Sophrology on the Pain Felt During a Bone Marrow Aspiration and Biopsy
The bone marrow aspiration and biopsy (BMAB) is an essential and indispensable examination for the diagnosis and the follow-up of the hematological diseases but which remains painful and dread by the patients.
- Conditions
- Hematologic Diseases, Diagnoses Disease, Pain
- Trial name
- BOM-ZEN (NCT04168983)
- Testing
- sophrology
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Caen
Lymphoma, Bone Marrow Neoplasm
PET Guided Bone Marrow Biopsy vs Trephine Bone Marrow Biopsy
Newly diagnosed lymphoma patients were recruited for FDG PET/CT and PET/CT guided bone marrow biopsy. All the patients also underwent routine bone marrow sampling from the posterior superior iliac spine.
- Trial name
- NCT05251168
- Testing
- PET Guided Bone Marrow Biopsy, Trephine Bone Marrow Biopsy
- Where
- India
- Volunteers
- 180 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh