Clinical trials: Bone Mass
Osteoporosis
Treatment of Osteoporosis - TOP 2-5 Clinical Studies (Pear Control)
Due to the fact that bone mineral density (BMD) is a not enough sensitive parameter for assessment of the bone quality and that the changes in BMD are gradually, extension of the clinical follow up is recommended.
- Trial name
- NCT05178719
- Testing
- PMA-zeolite
- Volunteers
- 81 people
- Sponsor
- Polyclinic K-center
Weight Loss, Bone Density
The Effect of Weight Loss and Dietary Protein Intake on Bone
The purpose of this study is to learn how the amount of protein during moderate weight loss influences bone health. We will also examine how two levels of protein intake affects diet quality.
- Trial name
- NCT00473031
- Testing
- Caloric restriction, high protein, Caloric restriction; normal protein, Counseling
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Neoplasms, Breast
Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study
This is a randomised, open label multicenter Phase III study comparing the efficacy of neoadjuvant lapatinib plus paclitaxel, versus trastuzumab plus paclitaxel, versus concomitant lapatinib and trastuzumab plus paclitaxel given…
- Trial name
- Neo ALTTO (NCT00553358)
- Testing
- Lapatinib, Trastuzumab, Paclitaxel
- Where
- 121 sites in Argentina, Belgium and 22 more
- Volunteers
- 455 people
- Sponsor
- Novartis Pharmaceuticals
Secondary Osteoporosis, Sarcopenia
The Effect of Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation on Bone Strength.
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical…
- Trial name
- NCT07325149
- Testing
- Exoskeleton-Assisted Walking (EAW) + active Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Bronx VA Medical Center
Depression, Healthy
Bone Loss in Premenopausal Women With Depression
The purpose of this study is to determine whether women with major depression lose bone mass at a faster rate than women without depression.
- Conditions
- Depression, Healthy, Osteopenia, Osteoporosis
- Trial name
- NCT00006180
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Osteoporosis, Bone Loss
Romosozumab in Women With Chronic SCI
This two-year open-label pilot clinical trial will evaluate the efficacy and safety of romosozumab to treat bone loss in females with chronic spinal cord injury (SCI) and osteoporosis (OP).
- Conditions
- Osteoporosis, Bone Loss, Osteopenia, Osteoporosis, Spinal Cord Injuries
- Trial name
- NCT04708886
- Testing
- Romosozumab, Alendronate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Northwestern University
Multiple Myeloma
A Phase IIa Study of Sotatercept on Bone Mass and Turnover in Patients With Multiple Myeloma
Lytic bone disease continues to be one of the most devastating complications of multiple myeloma (MM) despite recent and dramatic advancements in MM management, and bone lesions persist and can continue to significantly impact a…
- Trial name
- NCT02230917
- Testing
- Sotatercept
- Where
- United States
- Sponsor
- Rebecca Silbermann
Osteoporosis
Effects of Parathyroid Hormone in Men With Osteoporosis
Alendronate is a drug that blocks or reduces bone loss, while parathyroid hormone (PTH) stimulates the formation of new bone. The purpose of this study is to compare the bone-building effects of PTH alone, alendronate alone, and…
- Trial name
- NCT00000427
- Testing
- Parathyroid hormone, Alendronate
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Massachusetts General Hospital
Obesity in Children, Bone Strength
Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy
The goal of this clinical trial is to compare bone health markers over 24 months in participants 12 - 21 years of age with obesity who are starting the glucagon-like peptide-1 receptor agonists (GLP-1RAs) as compared to those…
- Conditions
- Obesity in Children, Bone Strength, GLP - 1, Lifestyle Modification
- Trial name
- NCT06903923
- Testing
- GLP-1 receptor agonist, Lifestyle intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Virginia
Soy Isoflavone Effect, Bone Density, Low
Effects of Soy Isoflavone on Bone Health Among Saudi Female Students Imam Abdulrahman Bin Faisal University.
Low bone mineral density (BMD) has recently increased among young women. Soy Isoflavone as a food supplement, has been found to have potent effect on bone health in postmenopausal women.
- Conditions
- Soy Isoflavone Effect, Bone Density, Low, Bone Density Increased
- Trial name
- NCT04547010
- Testing
- Soy Isoflavone supplement
- Where
- Saudi Arabia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Osteoarthritis, Hip
Dual Energy X-ray Absorptiometry (DXA) Comparison Hip Resurfacing Versus Total Hip Arthroplasty (THA)
This study compares the change (loss) of bone mineral density (BMD) that occurs in the proximal femur after hip resurfacing and total hip replacement.
- Trial name
- NCT01359527
- Testing
- Hip Resurfacing, Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Bone Mineral Density in Cow's Milk Allergic Patients
Young Adults With Life Threatening Cow's Milk Allergy: Risks of Decrease Bone Mineralization and Methods of Calcium Supplementation
Diet is the only source for calcium and the most important dietary source are dairy products. This presents a difficulty for children with IgE-mediated cow's milk allergy, who are unable to consume milk.
- Trial name
- NCT01930266
- Testing
- Experimental, Active comparator
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Soccer, Bone Density
Effect of the Interaction Between the Type of Artificial Turf and Boots Model of Bone Health in Children Soccer Players
The number of turf fields has experienced an important increase in public and private facilities during the last years. This artificial surface will be predominant in any soccer field in the next years.
- Conditions
- Soccer, Bone Density, Physical Fitness
- Trial name
- FUTBOMAS (NCT02399553)
- Testing
- Soccer boot intervention
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
In Recent Years, There Has Been a Rise in the Use of Immediate Loading Protocols, Dental Implant Stability
Effect of Topical Application of Atorvastatin Gel Versus Hyaluronic Acid on Immediate Loading Dental Implant in Posterior Maxilla
Background: In recent years, there has been a rise in the use of immediate loading protocols; however, the complex anatomy of the posterior maxilla presents challenges.
- Trial name
- NCT06976866
- Testing
- implant surgery
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Amira attia
Breast Cancer
Assessment of Quality of Life, Bone Density and Safety in Postmenopausal Breast Cancer Patients With Letrozole Therapy
To compare the overall QoL (Quality of Life) using Trial Outcome index (TOI) of FACT-B questionnaire for 3 years from baseline.
- Trial name
- NCT00913016
- Where
- South Korea
- Volunteers
- 897 people
- Sponsor
- Korean Breast Cancer Study Group
Osteoarthritis, Hip
Periprosthetic Bone Mineral Density Changes After Implantation Of A Short Hip Stem Compared To A Straight Stem
The aim of this study is to evaluate periprosthetic bone mineral density (BMD) changes in the proximal femur after implantation of the Fitmore compared to the CLS stem.
- Trial name
- NCT03147131
- Testing
- Total Hip Arthroplasty
- Volunteers
- 126 people
- Sponsor
- University Hospital Ulm
Growth Hormone Disorder, Adult Growth Hormone Deficiency
Effect of Somatropin on Left Ventricular Mass in Growth Hormone Deficient Adult Patients
This trial is conducted in Europe. The aim of this trial is to assess the effect of somatropin (Norditropin®) replacement therapy on the left ventricular mass of adult patients with a growth hormone deficiency.
- Trial name
- NCT01562834
- Testing
- somatropin
- Where
- 24 sites in France
- Volunteers
- 22 people
- Sponsor
- Novo Nordisk A/S
Osteogenesis Imperfecta
Translational Therapy in Patients With Osteogenesis Imperfecta - A Pilot Trial on Treatment With the Rankl-Antibody Denosumab
Pilot study to assess the efficacy of a therapy with the RANKL-antibody denosumab in children 5-10 years of age with mutation in COL1A1 or COL1A2 leading to Osteogenesis imperfecta.
- Trial name
- OI-AK (NCT01799798)
- Testing
- Denosumab
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Cologne
Image Changes of Lumbar Fusion, Bone Turnover Markers
The Effect of Zoledronic Acid to Bone Fusion and Bone Metabolism of Patients With Lumbar Degenerative Disease After Lumbar Interbody Fusion
Many patients who have lumbar degenerative disease suffer from osteoporosis or reduced bone mass or low bone mineral density. Among patients with lumbar degenerative disease, some need fusion surgery.
- Conditions
- Image Changes of Lumbar Fusion, Bone Turnover Markers, Bone Mineral Density
- Trial name
- NCT01310465
- Testing
- zoledronic acid, sodium chloride
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fudan University
Chronic Renal Failure, Hemodialysis
Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients
The comparison between nicotinamide and sevelamer aims to demonstrate, in chronic hemodialysed patients, the non-inferiority of nicotinamide in terms of control of the phosphatemia.
- Trial name
- NICOREN (NCT01011699)
- Testing
- nicotinamide, sevelamer, cinacalcet
- Where
- 18 sites in France
- Volunteers
- 176 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.