Clinical trials: Bone Mass
Alveolar Cleft Grafting
Combination of Bone Marrow Concentrate and Iliac Cancellous Bone Graft in Alveolar Cleft Grafting
The aim of this study will be to analyze the newly formed bone volume and density, 6 months after alveolar cleft grafting using iliac cancellous bone graft, with and without bone marrow concentrate.
- Trial name
- NCT04414423
- Testing
- bone marrow concentrate alveolar cleft grafting, Autogenous alveolar grafting
- Where
- 2 sites in Egypt
- Volunteers
- 18 people
- Sponsor
- Fayoum University
Rheumatoid Arthritis
Effects of Tofacitinib on Body Composition, Bone Mineral Density and Bone Marrow Adiposity in Patients With Rheumatoid Arthritis: the TOFAT Project
Inflammatory rheumatic diseases (IRD), such as rheumatoid arthritis, are characterized by adverse changes in body composition. Lean mass and bone mineral density are usually reduced while adiposity (total fat mass, visceral…
- Trial name
- TOFAT (NCT04175886)
- Testing
- Tofacitinib
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Chronic Kidney Disease, Osteoporosis
Clinical Study on a New Diagnostic Strategy for Osteoporosis and Sarcopenia in Chronic Kidney Disease Patients Based on MRI-FF
This is a single-center, observational cohort study aiming to validate the diagnostic value of MRI-FF in identifying osteoporosis and sarcopenia in patients with chronic kidney disease (CKD).
- Trial name
- NCT07645794
- Testing
- MRI-FF Scan
- Where
- China
- Volunteers
- 868 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Rett Syndrome
The Role of Dietary Calcium for the Treatment of Osteopenia in Girls With Rett Syndrome
Randomized, placebo-controlled trial of oral calcium supplementation for osteopenia in girls and women with Rett syndrome
- Trial name
- NCT05352373
- Testing
- calcium
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Osteoporosis
Effect of Soy Isoflavones on Bone Mineral Density and Physical Performance Indices
The aim of the present study was to investigate the effects of soy and soy plus isoflavones on bone mineral Density and physical performance in post menopausal women.
- Trial name
- SoyPTI (NCT00661856)
- Testing
- Soy protein
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Creighton University
Postmenopausal Osteoporosis
Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin of Postmenopausal Women With Low Bone Mass
The primary aim of the study is the comparative effect of zolendronic acid versus denosumab on serum sclerostin levels in postmenopausal women with low bone mass.
- Trial name
- DenoZol (NCT01572545)
- Testing
- Denosumab, Zoledronic acid
- Where
- 3 sites in Greece
- Volunteers
- 91 people
- Sponsor
- Aristotle University Of Thessaloniki
Hypertension, Aortic Aneurysm
Measurement of Heart-carotid Pulse Wave Velocity (hcPWV) by Laser Doppler Vibrometry (LDV)
Aortic stiffness is an important imaging biomarker of vascular aging. The ascending aorta is the most elastic segment, and it is excluded by reference non-invasive method carotid to femoral pulse wave velocity (PWV).
- Conditions
- Hypertension, Aortic Aneurysm, Bicuspid Aortic Valve, Marfan Syndrome
- Trial name
- InSide-CC (NCT05711693)
- Testing
- Laser doppler vibrometry (LDV), heart(cordium) carotid pulse wave velocity (ccPWV), Blood pressure and heart rate measurement, carotid to femoral PWW measurement
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Osteoporosis
Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis
Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury and even mortality.
- Trial name
- NCT01504230
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Hepatitis B
Change of Renal Function and Bone Mineral Density in CHB Patients Switch From TDF to TAF vs. Maintaining TDF
In Chronic hepatitis B (CHB) patients receiving long-term sequential Neucleos(t)ides(NAs), majority of these CHB patients experienced drug resistance and switched to Tenofovir disoproxil fumaratate(TDF).
- Trial name
- SWITAF (NCT03356834)
- Testing
- Tenofovir alafenamide(TAF), Tenofovir disoproxil fumarate(TDF)
- Where
- Hong Kong
- Volunteers
- 575 people
- Sponsor
- Humanity and Health Research Centre
Lymphoma, Osteoporosis
Evolution of Bone Mineral Density (BMD) in Patients With Lymphoma Undergoing Chemotherapy
The purpose of this study is to assess changes of bone mineral density (BMD) at 12 months during the therapeutic management of patients with lymphoma.
- Trial name
- LYMPHOS (NCT01841814)
- Testing
- Bone densitometry.
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Disorder of Bone Density and Structure, Unspecified, Vitamin D Deficiency
Nutritional Deficiencies Preventive Treatment Prior to Laparoscopic Sleeve Gastrectomy
This study will examine the effect of providing a structured program of daily nutritional supplements for a 8 weeks of intervention prior to Sleeve Gastrectomy bariatric surgery on bone mass density status and formation of…
- Trial name
- LSG (NCT02483026)
- Testing
- Multi vitamin, vitamin D
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Hadassah Medical Organization
HIV
Multicentre Study To Assess Changes In Bone Mineral Density Of The Switch From Tenofovir To Abacavir In Hiv-1-Infected Subjects With Loss Of Bone Mineral Density
Most of studies have not found any consistent drug-specific association with bone loss and controversial data with respect the effect of protease inhibitors (PIs) have been published.
- Trial name
- NCT01153217
- Testing
- Switch from tenofovir to abacavir
- Where
- 2 sites in Spain
- Volunteers
- 54 people
- Sponsor
- Germans Trias i Pujol Hospital
Barrett's Esophagus, Erosive Esophagitis
To Learn How Bone Structure and Bone Mass Change After Long-term PPI Use
Patients with severe acid reflux and/or Barrett's esophagus are recommended to take Proton pump inhibitors (PPIs)indefinitely to prevent complications such as strictures or the development of a type of esophageal cancer.
- Conditions
- Barrett's Esophagus, Erosive Esophagitis, Gastroesophageal Reflux Disease(GERD)
- Trial name
- BE-CAST (NCT01306799)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Pennsylvania
Spinal Cord Injury, Bone Loss
Effect of Teriparatide, Vibration and the Combination on Bone Mass and Bone Architecture in Chronic Spinal Cord Injury
Spinal cord injury (SCI) results in marked acute loss of bone. This study evaluates the effect of teriparatide (PTH) and the use of vibration as a form of mechanical stimulation on bone mass.
- Conditions
- Spinal Cord Injury, Bone Loss, Osteoporosis
- Trial name
- NCT01225055
- Testing
- Teriparatide, vibration
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Thomas J. Schnitzer
Osteoporosis, Hypomagnesemia
EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy
Proton pump inhibitors (PPIs) are widely used for the control of gastric ulcer-gastritis, erosive esophagitis (gastroesophageal reflux disease), peptic ulcer disease (duodenal ulcer), and heartburn.
- Trial name
- NCT05998863
- Testing
- EffCaMgCit
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Rheumatoid Arthritis (RA), Osteoporosis
Bone Density Change in Postmenopausal Rheumatoid Arthritis
Rheumatoid arthritis is associated with systemic inflammation-mediated bone loss, leading to an increased risk of osteoporosis and fractures, particularly in postmenopausal patients.
- Trial name
- NCT07336693
- Testing
- Bone Density Test
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Istanbul University - Cerrahpasa
Tooth Loss
Primary and Secondary Elevations of Maxillary Sinuses: a Prospective Clinical Study in the Posterior Maxillary Region
About 40 people will participate in the study, which will be conducted at Southern Medical University Southern Hospital. All subjects need to sign an informed consent form before screening, and successful subjects can enter the…
- Trial name
- NCT06106321
- Testing
- Transalveolar crest maxillary sinus floor lift, transalveolar crest parietal maxillary sinus floor secondary lift
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Osteopenia
A Comparison of Changes in Bone Density With the Same Bone-health Plan, But With Different Bone-health Supplements
A comparison of changes in bone density following the same bone-health plan, but with a different bone-health supplement.
- Trial name
- NCT01114685
- Testing
- AlgaeCal-1, AlgaeCal-2
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Integrative Health Technologies, Inc.
Joint Disease
Evaluation of Bone Mineral Density Changes After Total Hip Replacement: A Two-Year Clinical and DXA Analysis
Sponsor is conducting this post-market study to evaluate the clinical outcome and femoral bone mineral density (BMD) changes associated with the PROFEMUR® PRESERVE hip stem when used as indicated for primary total hip…
- Trial name
- NCT02865447
- Testing
- total hip arthroplasty implant
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- MicroPort Orthopedics Inc.
Osteoporosis
Investigation of the Effect of BONISTEIN(R) Bone Blend on Bone Mineral Density/Content and Biomarkers of Bone Health
The purpose of this study is to obtain information about the effect of a combination of genistein, PUFAs, vitamin K and D (BONISTEIN(R) bone blend) on bone health, determined as bone mass density/content and bone biomarkers after…
- Trial name
- NCT00698984
- Testing
- BONISTEIN(R) bone blend
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
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