Clinical trials: Bone Mass
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Plugs in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) plugs help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07484997)
- Testing
- Concentrated Growth Factor (CGF) Plug
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lupus Erythematosus, Systemic, Sjogren's Syndrome
Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome
The purpose of the study is to examine whether dehydroepiandrosterone (DHEA) administration improves fatigue and general well-being in patients with systemic lupus erythematosus or primary Sjögren's syndrome
- Trial name
- NCT00391924
- Testing
- Dehydroepiandrosterone
- Where
- 2 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- UMC Utrecht
Breast Cancer (Triple Negative Breast Cancer (TNBC)), Renal Cell Carcinoma (Kidney Cancer)
Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and work by blocking protein interactions that normally prevent the immune system from recognizing and destroying cancer cells.
- Conditions
- Breast Cancer (Triple Negative Breast Cancer (TNBC)), Renal Cell Carcinoma (Kidney Cancer), Melanoma (Skin Cancer), Non-Small Cell Lung Cancer
- Trial name
- NCT07555210
- Testing
- Dual-Energy X-ray Absorptiometry (DXA), High Resolution peripheral Quantitative Computed Tomography (HRpQCT)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Jessica Mezzanotte Sharpe
Osteoporosis
Sequential Treatment of Postmenopausal Women With Primary Osteoporosis (FP-001-IM)
The objective is to show superior efficacy of PTH (1-84) over risedronate in treating osteoporotic women for 12 months after having previously been treated with PTH (1-84) for 12 months followed by 12 months treatment with…
- Trial name
- PEAK (NCT00365456)
- Testing
- Parathyroid Hormone (PTH), Risedronate
- Where
- Denmark
- Volunteers
- 407 people
- Sponsor
- Takeda
Magnesium Deficiency, Calcium Metabolism Disorders
How Does Magnesium Status Influence Calcium Homeostasis?
The investigators aim to recruit 60 women who have agreed to participate in an existing randomized, double-blind, placebo-controlled trial (Treatment of Vitamin D Insufficiency, HSC 2009-0055).
- Trial name
- NCT01593501
- Testing
- vitamin D3
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Bone Density, Low
Comparing the Hydrodynamic Piezoelectric Technique With Osseodensification for the Assessment of Internal Sinus Iift-ing
Successful osseointegration considered the cornerstone in implant stability which predict the highest implants success outcomes.
- Trial name
- RCT (NCT06285903)
- Testing
- internal sinus lift surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Bone Density, Cancer
Screening of Bone Mineral Density in Women Who Have Received Chemotherapy
The hypothesis is that postmenopausal women who have received chemotherapy have a greater bone loss than the same age controls. The aim of this study is to obtain baseline bone mineral density (BMD) data on women with breast and…
- Trial name
- NCT00603551
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Medical University of South Carolina
Chronic Pain, Fibromyalgia
Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women
Chronic pain disproportionately affects women and may coexist with impaired bone health, particularly during midlife and after menopause.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoporosis, Orofacial Pain
- Trial name
- ORION (NCT07783295)
- Testing
- Full-Spectrum Cannabis Extract 5:1 (CBD:THC)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Associação Pan-Americana Multidisciplinar de Endocanabinologia
Spinal Cord Injury (=3 Years), Sublesional Bone Loss Secondary to SCI
Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
Treatment for sublesional bone loss (osteoporosis) in persons with chronic, motor-complete spinal cord injury (SCI) has been limited and unsuccessful to date.
- Trial name
- Chronic Romo (NCT04232657)
- Testing
- Romosozumab, Denosumab
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Marfan Syndrome, Marfan Syndrome Cardiovascular Manifestations
Living With Marfans and Your Aorta: Surgical Outcomes Study
Marfan Syndrome (MFS) is a genetic disease affecting the eyes, skeleton, heart and arteries. Despite MFS affecting multiple organ systems, cardiovascular manifestations are the most serious and life threatening.
- Trial name
- LIMA II (NCT04776681)
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Barts & The London NHS Trust
Weight, Body Fat Disorder
Clinical Trail of Transtek Glass Body Fat Analyzer
The clinical protocol of the clinical testing of this device: 1. Objective of the test: To verify the functions and efficiency of devices. 2. Test methods and procedures: Comparison Test. 3.
- Conditions
- Weight, Body Fat Disorder, Bone Mass
- Trial name
- GBFA (NCT01440894)
- Testing
- Comparison test
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Leo Wang
Osteoporosis
Yoga Improves Bone Density and Metabolism in Elderly Osteoporosis
This study was designed to evaluate the impact of a 16-week yoga program on BMD, bone metabolism markers, and physical fitness in elderly patients with OP.
- Trial name
- NCT07126002
- Testing
- Yoga
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Sport University
Obesity
Smallest Significant Value in Osteodensitomery in an Obese Population
The aim of this study is to determined the smallest significant value in osteodensitometry in obese population. The study population will be divided in 3 groups according to their BMI.
- Trial name
- PPVS-ob (NCT04301427)
- Testing
- Bone mineral density
- Where
- France
- Volunteers
- 120 people
- Sponsor
- CHU de Reims
Spondylolisthesis, Spinal Fusion
Intercorporal Bone Graft Measurement Study
Instrumented lumbar fusion surgery is often accompanied by interbody fusion using an autologous bone graft that is supposed to expand and remodel to achieve a rigid and lasting bony construction between two vertebrae.
- Trial name
- NCT05565456
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Rijnstate Hospital
Bone Mineral Density Reference Data
Bone Mineral Accretion in Young Children
Compromised bone strength and increased fracture susceptibility pose significant morbidity and health care costs in children. Inadequate childhood bone accretion also may have lifelong consequences.
- Trial name
- NCT02162602
- Where
- 2 sites in United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Marfan Syndrome, Marfan Related Disorders
Development of a Blood Test for Marfan Syndrome
The objective of this study is to determine whether a simple blood test can be a useful clinical tool for monitoring aortic disease in Marfan syndrome and Marfan-related disorders.
- Conditions
- Marfan Syndrome, Marfan Related Disorders, Control Subjects
- Trial name
- NCT02148900
- Where
- 5 sites in United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Osteoporosis (Senile)
To Study the Efficacy and Safety of Doxercalciferol on Spinal and Femoral Density in Postmenopausal Osteopenic Women in a Long Term 2 Year Study
A clinical trial to compare the effect of doxercalciferol or placebo in preventing bone loss from the spine and femur in postmenopausal women
- Trial name
- NCT07660536
- Testing
- doxercalciferol capsules, Hectorol®
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Creighton University
Dental Implant Failed, Jaw, Edentulous, Partially
Osseodensification Versus Conventional Drilling for Implant Site Preparation
A total of 34 participants, who require replacement of an anterior or posterior single tooth with dental implant, will be randomly allocated to two equal sized groups.
- Conditions
- Dental Implant Failed, Jaw, Edentulous, Partially, Edentulous Alveolar Ridge, Osseointegration Failure of Dental Implant
- Trial name
- NCT06034067
- Testing
- Osseodensification osteotomy preparation, Standardized osteotomy preparation
- Where
- United Arab Emirates
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Iron Deficiency, Iron Deficiency Anemia (IDA)
Collegiate Athlete Study
The purpose of this study is to determine what percentage of Black collegiate athletes have low energy availability. It will also determine the percentage of Black collegiate athletes who have iron deficiency, suboptimal or low…
- Conditions
- Iron Deficiency, Iron Deficiency Anemia (IDA), Vitamin D Deficiency, Vitamin D Insufficiency
- Trial name
- NCT07631312
- Testing
- Iron and Vitamin D Deficiencies Correction
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Osteoporosis, Growth Hormone Deficiency
Randomized Study of Growth Hormone on Bone Mineral Density in Patients With Adult Onset Growth Hormone Deficiency
OBJECTIVES: I. Compare whether the bone tissue in the spine and hip improves in patients with adult onset growth hormone deficiency treated with growth hormone (GH) vs placebo. II.
- Trial name
- NCT00006394
- Testing
- growth hormone
- Where
- 7 sites in United States
- Volunteers
- 72 people
- Sponsor
- National Center for Research Resources (NCRR)
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