Clinical trials: Bone Pain
Class III Malocclusion, Cross Bite
Evaluation of Pain, Discomfort and Acceptance During the Orthodontic Treatment of Class III Malocclusion
The aim of this study is to evaluate the levels of pain, discomfort and acceptance between two treatment modalities of Class III correction of growing patients in the late mixed dentition period.
- Conditions
- Class III Malocclusion, Cross Bite, Orthodontic Appliance Complication
- Trial name
- NCT03976635
- Testing
- Removable Mandibular Retractor, Bone-anchored intermaxillary traction
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Osteoporotic Vertebral Fracture, Neuropathic Pain
Osteoporotic Fracture and Lidocaine Plaster 5% for Neuropathic Pain preventioN
Osteoporotic vertebral fractures may lead to chronic pain with a neuropathic component, which is often underdiagnosed and undertreated in older adults.
- Trial name
- FLYNN (NCT07691359)
- Testing
- Lidocaine 5% medicated plaster
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Degenerative Spondylolisthesis
Safety Evaluation of ART352-L in Subjects Undergoing Posterolateral Spinal Fusion
Ankasa Regenerative Therapeutics, Inc. (Ankasa) is developing ART352-L, a liposomal formulation of recombinant human Wnt3A protein, that is applied ex vivo, to harvested autologous bone grafts (autograft) to enhance the…
- Trial name
- NCT04378543
- Testing
- ART352-L
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Ankasa Regenerative Therapeutics, Inc.
Pain, Postoperative
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
The purpose of this study is to determine whether, for surgery of the tibia, one dose of methadone provides better control of pain afterward as compared to morphine, which is the usual drug given to control pain after surgery.
- Trial name
- NCT01430182
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Bone Metastases, Pain
Cryosurgery and Radiation Therapy in Treating Patients With Painful Bone Metastases
This pilot clinical trial studies cryosurgery and radiation therapy in treating patients with painful bone metastases. Cryosurgery kills tumor cells by freezing them.
- Trial name
- NCT01767935
- Testing
- cryosurgery, radiation therapy, quality-of-life assessment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Wake Forest University Health Sciences
Spinal Stenosis
Epidural Intervention of Spinal Nerves With Tumor Necrosis Factor-Alpha Inhibitor
This study is to assess the clinical efficacy of epidural injections with Tumor Necrosis Factor-Alpha(TNF-α) Inhibitor in patients with chronic radicular pain caused by lumbar spinal stenosis.
- Trial name
- NCT04062474
- Testing
- Epidural Intervention with TNF-α inhibitor
- Volunteers
- 90 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pain, Hip Fracture
PENG vs. FIC Block for Hip Fracture ED Patients
Ultrasound-guided nerve blocks are an important tool for treating pain due to orthopedic injury in the ED. They provide long lasting, opioid-sparing pain relief that is generally safe and well-tolerated by patients1.
- Trial name
- NCT05102760
- Testing
- Nerve Block using FIC Proceedure, Nerve Block using PENG Proceedure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Antonios Likourezos
Osteoarthritis, Rheumatoid Arthritis
Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder
The aim of this study is to find out how patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis receiving NSAID-therapy are treated and managed by their doctor in usual clinical practice, how patients…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EVIDENCE (NCT01176682)
- Where
- 244 sites in Belgium, France and 10 more
- Volunteers
- 1,149 people
- Sponsor
- AstraZeneca
Fractures, Bone
Cast Art for Kids With Extremity Fractures
The goal of this clinical trial is to compare casts with cast art versus those without art in children who sustain a fracture of the extremity.
- Trial name
- CAKE POP (NCT06990555)
- Testing
- Neutral White Cast, Color Wrapped Cast, Cast with Cast Art
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Metastasis to Bone, Radiotherapy
A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases
This is a phase III randomized-controlled, single-blind study comparing the standard schedule for antalgic radiotherapy of a single fraction of 8.0 Gy delivered through three-dimensional conformal radiotherapy (3D-CRT) to a…
- Conditions
- Metastasis to Bone, Radiotherapy, Neoplasm Metastasis
- Trial name
- ROBOMET (NCT03831243)
- Testing
- Stereotactic body radiotherapy, 3D-conformal radiotherapy
- Where
- Belgium
- Volunteers
- 126 people
- Sponsor
- Cancer Research Antwerp
Lumbar Disc Herniation
Evaluation of the Effectiveness of Focused Radiofrequency (TECAR) Therapy on Pain, Disability, Function, and Quality of Life in Patients With Lumbar Disc Herniation
Low back pain is a very common health problem in societies, regardless of the underlying cause. Its lifetime prevalence has been reported to be as high as 75-80%.
- Trial name
- TECAR THERAPY (NCT07335718)
- Testing
- TECAR THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Ankle Sprains, Ankle Fractures
Accumulative Effects of Talus Mobilization
The purpose of this study is to verify the effect of anteroposterior talus mobilization on range of motion, pain, and functional capacity in participants with sub-acute and chronic ankle injuries.
- Conditions
- Ankle Sprains, Ankle Fractures, Ankle Dislocations, Ankle Bruises
- Trial name
- NCT02244008
- Testing
- joint mobilization, manual contact
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Federal University of Minas Gerais
Spinal Stenosis, Low Back Pain
Total Facet Arthroplasty System®(TFAS®) Clinical Trial
The Archus Total Facet Arthroplasty System® (TFAS®) is a non-fusion spinal implant indicated for treatment of patients with moderate to severe spinal stenosis. TFAS® replaces the diseased facets following surgical removal.
- Conditions
- Spinal Stenosis, Low Back Pain, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- NCT00418197
- Testing
- Total Facet Arthroplasty System® (TFAS®)
- Volunteers
- 450 people
- Sponsor
- Archus Orthopedics, Inc.
Cervical Radicular Pain, Spondyloarthritis (SA)
Assessment and Rehabilitation in Cervical Radiculopathy
The investigators perform a prospective controlled study and analyse the effects of a rehabilitation program, including oral anti-inflammatory drugs, nutraceutical - ProHumano+ SpineDinamic (PHSD), physical therapy and kinetic…
- Conditions
- Cervical Radicular Pain, Spondyloarthritis (SA), Neuropathic Pain Management, Quality of Life (QOL)
- Trial name
- NCT07054450
- Testing
- All patients in the study will be included in rehabilitation program, Study Group will receive a nutraceutical product daily, 3 months.
- Where
- Romania
- Volunteers
- 110 people
- Sponsor
- Filantropia Hospital
Lumbar Disc Herniation
Strengthening Exercise and Activities of Daily Living Instructions for Patients With Lumbar Disc Herniation
Lumbar disc herniation (LDH) is one of the most common causes of mechanical low back pain (LBP) associated with radiating leg pain.
- Trial name
- NCT05021718
- Testing
- Strengthening exercises, Pharmacological therapy, Hot compression
- Where
- Bangladesh
- Volunteers
- 70 people
- Sponsor
- Chittagong Medical College
Femur Fracture, Hip Surgery
Pericapsular Nerve Group (PENG) Block on Pain During Participant Positioning for Spinal Anesthesia in Hip Fracture Surgery
Hip fracture surgery is a common orthopedic procedure, especially in elderly patients. These fractures are quite common in adults over the age of 65, and the one-year mortality rate ranges from 12% to 37%.
- Trial name
- NCT06813755
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University
Hip Fracture
A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for…
- Trial name
- NCT01547468
- Testing
- Femoral Nerve Catheterization, Intravenous Opioids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leslie Thomas
Cervical Spondylosis
Kinesthetic Exercises and Sine Sound Waves in Cervical Spondylosis
The goal of this Randomized control trial is to determine the Effect of kinesthetic exercises and sound waves on pain, ROM, shoulder alignment and disability in cervical spondylosis.
- Trial name
- NCT06351254
- Testing
- Sine sound waves, Kinesthetic exercises, Sine sound waves plus kinesthetic exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Low Back Pain, Recurrent Lumbar Disc Herniation
Surgical Treatment Comparison for Recurrent Lumbar Disc Herniation
The purpose of this study is to compare patients who underwent decompression/discectomy with pedicle screw fusion to patients who received decompression/discectomy without fusion.
- Trial name
- NCT00444405
- Sponsor
- Mercy Research
Type 2 Diabetes, Neuropathy, Painful
Methylglyoxal Evaluation in Humans
The investigators will test the hypothesis that patients with low back pain associated with lumbar disc aberrancy will have elevated MGO-protein levels circulating in the blood that are comparable to patients with painful…
- Conditions
- Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
- Trial name
- MEH (NCT05350553)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
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