Clinical trials: Bone Regeneration
Alveolar Ridge Preservation
2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone
Place a collagen plug (collagen plug) in the lower 2/3 to 1/2 of your tooth extraction site while giving you Vit. The extracted teeth are made into autogenous tooth root thin slices and covered in your tooth extraction cavity…
- Trial name
- NCT06141239
- Testing
- Autologous Tooth Root, Vit.D3, bone graft
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Bone Loss, Occlusion
Comparative Clinical and Radiographical Evaluation of Treatment of Angular Bone Defect Related to Over Erupted Tooth Using GTR Followed by Orthodontic Intrusion Versus Orthodontic Intrusion Followed by GTR
Occlusal prematurity leading to loss of vertical stopping points between teeth can lead to teeth over eruption creating abnormal contact area which favors food accumulation and plaque retention.
- Trial name
- NCT05371418
- Testing
- surgical (guided tissue regeneration), orthodontic intrusion followed by guided tissue regeneration GTR
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Bone Resorption
Guided Bone Regeneration With Customized Titanium Meshes
The aims of this prospective clinical study are to evaluate: a) the effectiveness of digitally customized titanium meshes in association with autologous bone particles and bovine bone mineral and covered with collagen membranes…
- Trial name
- NCT04480073
- Testing
- Customized CAD-CAM Titanium Mesh (Y-xoss CBR® by Reoss -Filderstadt - Germany) for Guided Bone Regeneration of atrophic alveolar ridges
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Milan
Mandibular Fractures
Bone Regeneration With Mesenchymal Stem Cells
Mandible fractures are a common cause of facial injury in adults. The autologous mesenchymal stem cell (AMSC) transplantation, is proposed as an alternative to the conventional graft treatment, improving bone neoformation.The…
- Trial name
- NCT02755922
- Testing
- Application of autologous mesenchymal stem cells
- Volunteers
- 20 people
- Sponsor
- Instituto Mexicano del Seguro Social
Wound Healing, Bone Regeneration
Fucoidan(Seaweed) Based Gel Around Osseous Defects
The current study is a prospective case series study to evaluate the effect of Fucoidan gel around osseous defects to assess the wound healing and bone regeneration
- Trial name
- NCT07793851
- Where
- India
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Immediate Dental Implant Placement, Connective Tissue Graft
Immediate Implants in Front Teeth With Bone Loss: Regeneration and Temporary Crown in a Randomized Clinical Study
This clinical trial investigates the biological and clinical outcomes of immediate implant placement in aesthetic areas presenting with buccal bone dehiscence.
- Conditions
- Immediate Dental Implant Placement, Connective Tissue Graft, Connective Tissue Graft Harvesting, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- GBR / RCT (NCT07415486)
- Testing
- immediate implant placement with DBBM-C and connective tissue graft, immediate implant placement with DBBM-C with collagen membrane
- Volunteers
- 24 people
- Sponsor
- Universitat Internacional de Catalunya
Bone Resorption After Tooth Extraction
Buccal Plate Expansion Technique Versus Guided Bone Regeneration Technique in Socket Preservation in the Aesthetic Zone.
Introduction and evaluation of a new technique for socket preservation involving internal expansion of the buccal plate of the extraction socket using internal flapless corticotomy and bone grafting the extraction socket with…
- Trial name
- NCT03065803
- Testing
- Buccal plate expansion technique for dental socket preservation, Guided bone regeneration technique for post-extraction dental socket preservation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Passant Khaled Tayaa
Ovarian Reserve
Bone Marrow Transplantation to Promote Follicle Recruitment in Poor Ovarian Reserve
Women delay maternity and, as a consequence, available oocyte number and their quality decrease (9-18% of all IVF patients). Different treatment protocols have been developed nevertheless none of them optimal: the number of…
- Trial name
- NCT02240342
- Testing
- Bone marrow transplant into ovarian artery
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitario La Fe
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Periapical Lesions
Evaluation of Bone Regeneration After Apical Surgery Using Advanced Platelet-rich Fibrin: Utilization of Ultrasound for the Assessment of Periapical Lesions
The study examines the impact of advanced platelet-rich fibrin (A-PRF) on bone regeneration in apical surgery compared to standard methods.
- Trial name
- EBRAAPUU (NCT06734962)
- Testing
- Apical surgery procedure using A-PRF, Apical surgery without using A-PRF
- Where
- Latvia
- Volunteers
- 44 people
- Sponsor
- Riga Stradins University
Alveolar Ridge Defect
CopiOs® Pericardium Membrane for Localized Alveolar Ridge Augmentation
This is a prospective, multi-center study to evaluate the use of CopiOs Pericardium Membrane, a bovine xenograft, with use of Puros Cancellous Particulate Allograft, for the augmentation of localized alveolar ridge defects on…
- Trial name
- NCT00889265
- Testing
- CopiOs Pericardium Membrane
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Zimmer Biomet
Guided Bone Regeneration, Bone Augmentation
Lateral GBR Using Two Types of Membrane With a Combination of Allograft-xenograft
Bone width is critical for successful implant placement, as thin bone increases the risk of bone loss. Various augmentation techniques-especially guided bone regeneration (GBR)-are effective in restoring bone volume using grafts…
- Trial name
- NCT07525128
- Testing
- Lateral Guided bone regeneration
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Jaw Cysts
Volumetric Analysis of Bone Following Jaw Cysts Enucleation With and Without Alb-PRF
Cyst is the main cause for longstanding swelling in the mandible or the maxilla, its enlargement usually results in resorption and weakening of bone.
- Trial name
- NCT05658900
- Testing
- Enucleation with albumin PRF, Enucleation without albumin PRF
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Hams Hamed Abdelrahman
Bone Loss, Alveolar
Tenting Screws in Combination With Platelet Concentrate for Vertical Alveolar Ridge Augmentation
Alveolar bone resorption often occurs after tooth extraction. At present, guided bone regeneration technique is widely used in clinic since it leads to less trauma and less complications.
- Trial name
- NCT04835532
- Testing
- guided bone gereration
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Alveolar Bone Loss, Pathological Conditions, Anatomical
Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures
The purpose of this study is to examine if a biologically active commercially available amnion chorion membrane (ACM) is as effective as the commercially available inert dense polytetrafluoroethylene membrane (D-PTFE) in…
- Trial name
- NCT02602223
- Testing
- Placing Amnion chorion membrane over grafted site, Placing d-PTFE membrane over grafted site
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Indiana University
Bone Loss, Bone Lesion
Hyaluronic Acid +Hydroxyapatite Vs Hydroxyapatite in Bone Regeneration
Evaluation of the effect of hyaluronic acid with hydroxyapatite versus hydroxyapatite alone on bone regeneration following enucleation of mandibular odontogenic cyst.
- Trial name
- NCT05957926
- Testing
- hyaluronic acid added to hydroxyapetite, Hydroxyapatite alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Guided Bone Regeneration, Dental Implant
Submerged Vs Non-Submerged Guided Bone Regeneration Simultaneous to Implant Placement.
Dental implants are worldwide recognized one of the best manners to replace lost or hopeless prognosis teeth. There are different variables that creates proper conditions for long-term prognosis of implant treatments.
- Conditions
- Guided Bone Regeneration, Dental Implant, Submerged Regeneration, Bone Atrophy
- Trial name
- NCT06695338
- Testing
- Guided Bone Regeneration (Submerged), Guided Bone Regeneration (Non-submerged)
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya