Clinical trials: Bone Resorption
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation?
Even after atraumatic tooth removal and/or immediate implant placement, some reduction of the alveolar ridge dimension is expected.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Enlargement, Tooth Extraction, Hyaluronic Acid
- Trial name
- NCT07496437
- Testing
- DBBM + FGG, Hyaluronic acid + collagen sponge + FGG
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Periodontal Bone Loss
Decortication With Calcium Phosphosilicate Putty in the Treatment of Non-contained Intrabony Periodontal Defects
To overcome the disadvantage of complex morphology and availability of less favorable support to retention of graft and clot stabilization in 1-, 1-2-wall periodontal defects, it was hypothesized that placement of CPS putty…
- Trial name
- NCT03435757
- Testing
- OFD+IMP+CPS, OFD+IMP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Alveolar Bone Loss, Bone Graft; Complications
Patient Satisfaction and Bone Gain Following Autogenous Particulate Sticky Bone Preparation With Xenograft Versus Without Xenograft for Grafting of Maxillary Anterior Knife Edge Ridge in Partially Edentulous Patients for Implant Placement
The aim is to evaluate the value and efficiency of sticky bone in the augmentation of alveolar ridge deficiency when being used with or without xenogenic bone graft for esthetic implant placement.
- Trial name
- NCT03556111
- Testing
- Sticky bone augmentation
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases, Periodontal Bone Loss
Entire Papilla Preservation Technique in the Treatment of Periodontal IntraBony Defects: a 1-year Follow-up Study
The aim of this study was to investigate the radiographic and clinical outcomes associated with the whole papilla preservation technique in the treatment of isolated intraosseous defects in patients with stage III periodontitis.
- Trial name
- EPP (NCT06744348)
- Testing
- ENTİRE PAPİLLA PRESERVATİON
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Osteoporosis
Thai Traditional Massage Increases Biochemical Marker of Bone Formation in Postmenopausal Women
To investigate the skeletal effect of Thai traditional massage by examining the changes in biochemical markers of bone turnover.
- Trial name
- NCT01627028
- Testing
- Thai traditional massage
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Edentulous Jaw
Adjunctive Benefit of Xenograft Plus a Membrane During Sinus Crestal Approach
Patients in need for implant-supported restoration in maxillary posterior sites with insufficient residual bone height will be randomly allocated to two different arms.
- Trial name
- NCT04662333
- Testing
- Transcrestal approach for sinus lift, Xenograft application
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Siena
Bone Loss, Alveolar
Evaluation of Regenerative Potential in Horizontal Bone Loss Using VCMX Along With LASER Therapy
Background- Periodontitis, an inflammatory disease of the periodontium, is one of the major causes of tooth mortality. Of all the bone destruction patterns that are present in periodontitis, horizontal bone loss is the most…
- Trial name
- NCT06204588
- Testing
- control group: SFA only, Test group 1: VCMX + Low level LASER therapy + Single flap approach, Test group 2: Low level LASER therapy + Single flap approach
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Regeneration of Human Intrabony Defects With rhFGF-2/HA
BACKGROUND: Periodontal disease is an infection that results in progressive loss of dental support, which may lead to tooth loss..
- Trial name
- NCT02337166
- Testing
- a gel containing 4mg/ml rhFGF-2 in sodium hyaluronate, Periodontal flap surgery
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Bone Resorption
Low Speed Drilling Versus Conventional Drilling Technique on Crestal Bone Level in Maxilla.(Group B ) A Randomized Controlled Clinical Trial
20 patients were selected requiring implant placement and divided randomly into two groups (10 in each group) for the study group, starter drill is used to locate the point of insertion as planned then pilot drill is also used to…
- Trial name
- NCT03212820
- Testing
- Drilling at low speed, Drilling at conventional or high speed
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Crestal Bone Loss
Soft Tissue Esthetic With Autogenous Dentin Chips and Immediate Implantation Versus Conventional Immediate Implantation With Xenograft in Thin Buccal Bone
After tooth extraction, host bone resorption and atrophy of alveolar ridge may be observed. Bone resorption occurs specially in incisors and premolar area of jaw in region of thin buccal bone that may lead to change in contour.
- Trial name
- NCT03544580
- Testing
- immediate implant with dentine chips, conventional immediate implant
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Dental Implant Failure Nos, Alveolar Bone Loss
Ridge Splitting With Implant Placement Using Autogenous Tooth Graft
The aim of this study is to evaluate the radiographic and the clinical outcomes of application of the alveolar ridge splitting (ARS) in combination with ATG, associated with immediate implant placement versus ARS in combination…
- Conditions
- Dental Implant Failure Nos, Alveolar Bone Loss, Peri-Implantitis
- Trial name
- NCT06131541
- Testing
- autogenous tooth graft, autogenous bone graft
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Alveolar Bone Loss
Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials
The study is a two-arm, parallel-design, randomized, prospective clinical trial designed to examine histologic wound healing following ridge preservation using bovine xenograft and porcine xenograft materials.This protocol…
- Trial name
- NCT02802319
- Testing
- Porcine Xenograft (Zcore), Bovine Xenograft (Bio-Oss)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Feeding Patterns, Bone Resorption
Effect of Fasting Versus Feeding on the Bone Metabolic Response to Running
This study examined changes in bone metabolism (markers of bone turnover, calcium metabolism) with a bout of acute treadmill running preceded by either a single, mixed meal or an overnight fast.
- Trial name
- NCT01505348
- Testing
- Overnight fast
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- QinetiQ Ltd
Alveolar Bone Loss
Alveolar Ridge Preservation Techniques After Tooth Extraction
The aim of the present randomized controlled trial (RCT) was to evaluate the efficacy of different alveolar ridge preservation (ARP) techniques on hard tissue dimensional alterations after tooth extraction, based on clinical…
- Trial name
- NCT04934813
- Testing
- Alveolar ridge preservation
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Bone Resorption
State of the Art Immediate Implant Placement in the Premaxilla
The goal of this clinical study is to learn how well immediate implant placement works in the front upper jaw (premaxilla) when using flapless guided surgery, hard and soft tissue augmentation, and immediate provisional crowns.
- Trial name
- NCT07080710
- Testing
- Immediate implant placement
- Where
- 2 sites in Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Ghent
Alveolar Bone Resorption, Graft Overgrowth
Histological and Volumetric Evaluation of Customized Allograft Bone Blocks
Customized bone blocks need CBCT and digital software to design the block needed to rehabilitate. Some advantages are reduced surgical time and better adaptation of the graft, leading to less complications.
- Conditions
- Alveolar Bone Resorption, Graft Overgrowth, Resorption of Bone Graft, Graft Complication
- Trial name
- NCT05937035
- Testing
- Customized allogenic bone block surgery
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Dental Implant
Accuracy of Guided Ridge Splitting With Simultaneous Implant Placement
Assessing whether is there a difference between computer-guided ridge splitting and conventional technique with simultaneous implant placement in patients with maxillary width deficiency.
- Trial name
- NCT06333912
- Testing
- dental implant placement with ridge splitting.
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alexandria University