Clinical trials: Bone Resorption
Bone Loss, Energy Supply; Deficiency
Cycling Duration and Bone Markers in in Active Young Adults
Exercise is an important factor in bone health. Sclerostin is one of the key molecules involved in bone response to mechanical loading.
- Trial name
- NCT04380155
- Testing
- Exercise
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brock University
Alveolar Bone Loss
Alveolar Bone Loss Around 3 Different Designs of Dental Implant: Prospective Comparative Clinical Trail
comparison of alveolar bone resorbtion/ changes for a period of 12 month post loading of different designs and brands of oral implants.
- Trial name
- NCT00544323
- Testing
- oral implant
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Marginal Bone Levels, Open Sinus Elevation
Marginal Bone Changes Around Dental Implant Placed With Open vs. Closed Sinus Elevation
Background: In cases with atrophic posterior maxilla, sinus elevation techniques are essential for a successful implant placement.
- Conditions
- Marginal Bone Levels, Open Sinus Elevation, Closed Sinus Elevation
- Trial name
- NCT06811337
- Testing
- Open Sinus Elevation, Closed Sinus Elevation
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Misr International University
Bone Resorption
Dietary Intake Modifications to Protect Against Changes in Bone Metabolism
Bone loss is not only a well-documented effect of spaceflight on astronauts, but also a condition that affects millions of men and women on Earth each year.
- Trial name
- ProK (NCT01713634)
- Testing
- Preflight, In-flight
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration (NASA)
Implant Tissue Failure
Effects of ABO Blood Types on the Survival and Marginal Bone Resorption of Dental Implants
This study evaluates implant survival and marginal bone resorption in patients receiving implant treatment with respect to demographic data and AB0 (groups) blood types.
- Trial name
- NCT04054271
- Where
- Turkey (Türkiye)
- Volunteers
- 963 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Depression, Healthy
Bone Loss in Premenopausal Women With Depression
The purpose of this study is to determine whether women with major depression lose bone mass at a faster rate than women without depression.
- Conditions
- Depression, Healthy, Osteopenia, Osteoporosis
- Trial name
- NCT00006180
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Periodontal Bone Loss, Periodontal Attachment Loss
Platelet-rich Fibrin and Autogenous Bone vs Enamel Matrix Derivative and Autogenous Bone in Intrabony Defects
Currently, the most positive documented outcomes of periodontal regenerative therapy (PRT) in intrabony defects (IBDs) have been achieved with a combination of bone grafts ( BGs) and a regeneration material like membranes in…
- Trial name
- NCT03510780
- Testing
- Periodontal surgery with Enamel Matrix Derivative, Periodontal surgery with Platlet Rich fibrin
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Alveolar Bone Loss, Pathological Conditions, Anatomical
Comparison of Amnion Chorion Membrane vs. Dense Polytetrafluoroethylene Membrane in Ridge Preservation Procedures
The purpose of this study is to examine if a biologically active commercially available amnion chorion membrane (ACM) is as effective as the commercially available inert dense polytetrafluoroethylene membrane (D-PTFE) in…
- Trial name
- NCT02602223
- Testing
- Placing Amnion chorion membrane over grafted site, Placing d-PTFE membrane over grafted site
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Indiana University
Type 2 Diabetes Mellitus
Effects of Gut Peptides on Bone Remodeling. KS-4-Diabetes-19
Both GLP-2 and GIP reduce the bone resorption (measured as CTX) in healthy persons. In this study, we will investigate wether GLP-2 and GIP is reducing CTX in persons with type 2 diabetes.
- Trial name
- NCT03867656
- Testing
- GLP-2, GIP
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Bone Atrophy, Alveolar
Apico-coronal Position of Tissue-level Implants Bone Stability
early marginal bone loss around dental implants may hamper long term prognosis of implant-prosthetic rehabilitation. this study aimed to study the correlation of pico-coronal position of dental implant (from supracrestal, crystal…
- Trial name
- NCT05363306
- Testing
- implant insertion
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Bone Atrophy, Alveolar
Tooth Roots for Lateral Alveolar Ridge Augmentation
A deficient alveolar ridge segment in prepara¬tion for implant placement can be regenerated by several techniques. The type of graft material for each patient depends on many factors such as the anatomy, the morphology of the…
- Trial name
- NCT04678674
- Testing
- tooth root augmentation
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Catherine Specialty Hospital
Preservation of Alveolar Bone Height With PLGA Bioscaffold
Radiographic Assessment of Bone Regeneration in Alveolar Sockets With PLGA Scaffold
After extraction of a tooth, the bony socket heals naturally but due to the absent of the tooth and any presence of support in the socket, bone resorption occur both vertically and bucco lingually or bucco palataly.
- Trial name
- NCT00836797
- Where
- 2 sites in India, Singapore
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bio-Scaffold International Pte Ltd
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Tooth Loss
Azento IIS 3 Year Outcomes Implant Study
The revised purpose of this study is to compare and evaluate the stability of the implant body, survival rate, bone-level changes, and the implant's soft-tissue outcomes over a period of 1 year.
- Trial name
- NCT04255342
- Testing
- Implant Placement and Temporary Crown using AstraTech Implant System EV, Final Crown Delivery
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Christopher Barwacz
Avulsion
Healing Assessment of External Inflammatory Root Resorption After Revascularization Technique of Avulsed Permanent Central Incisor (Case Study)
Evaluate the healing of external root resorption of replanted avulsed permanent maxillary central incisor after revascularization.
- Trial name
- (EIRR) (NCT06785961)
- Testing
- Regeneration of traumatic tooth
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Badr University
Implant, Peri-Implantitis
Efficacy of Diode Laser in Peri-implantitis
The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis.
- Conditions
- Implant, Peri-Implantitis, Alveolar Bone Loss, Complications
- Trial name
- NCT02362854
- Testing
- Conventional peri-implantitis treatment, DL application in peri-implantitis
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Lead, Blood, Pregnancy
Dietary Calcium Supplementation to Reduce Blood Lead in Pregnancy
Lead accumulates in bone. During pregnancy, physiologic changes occur prompting bone resorption in order to provide calcium to the growing fetal skeleton also release the lead stored in bone into a pregnant woman's circulation.
- Conditions
- Lead, Blood, Pregnancy, Bone Resorption
- Trial name
- NCT00558623
- Testing
- calcium carbonate
- Where
- Mexico
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Alveolar Bone Loss, Bone Graft; Complications
Patient Satisfaction and Bone Gain Following Autogenous Particulate Sticky Bone Preparation With Xenograft Versus Without Xenograft for Grafting of Maxillary Anterior Knife Edge Ridge in Partially Edentulous Patients for Implant Placement
The aim is to evaluate the value and efficiency of sticky bone in the augmentation of alveolar ridge deficiency when being used with or without xenogenic bone graft for esthetic implant placement.
- Trial name
- NCT03556111
- Testing
- Sticky bone augmentation
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Use of Hyaluronic Acid Gel in Intraosseous Defects
Aim: The aim of this randomised, parallel-arm, blinded, controlled clinical trial was to compare the clinical and radiographic efficacy of MINST with and without 0.8% HA gel application in the treatment of intraosseous defects.
- Trial name
- NCT06214728
- Testing
- Hyaluronic acid gel application
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University