Clinical trials: Bone Resorption
Alveolar Bone Loss, Edentulous Maxilla, Atrophic
Guided Bone Regeneration Combined With PRGF for Atrophic Edentulous Maxilla
This prospective interventional clinical study evaluated guided bone regeneration combined with plasma rich in growth factors for vertical and horizontal augmentation of the atrophic edentulous maxilla.
- Conditions
- Alveolar Bone Loss, Edentulous Maxilla, Atrophic, Alveolar Ridge Deficiency, Jaw Atrophy
- Trial name
- GBR-PRGF-Maxil (NCT07654218)
- Testing
- Guided Bone Regeneration Combined With Plasma Rich in Growth Factors
- Where
- Portugal
- Volunteers
- 11 people
- Sponsor
- Universidade do Porto
Postmenopausal Osteopenia
The Effect of Aerobic Exercise on Bone Turnover Markers in Postmenopausal Patients
The aim of the study was to evaluate the effect of light-moderate aerobic exercise on BMD in postmenopausal osteopenic women using bone formation-resorption markers.
- Trial name
- NCT06866561
- Testing
- aerobic exercise, cholecalciferol, calcium carbonate
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Periodontal Diseases, Periodontal Bone Loss
Adjunctive Antioxidant Effect of Centella Asiatica Nanoemulsion Gel in Management of Periodontitis
The aims of the current study are: 1. Evaluation of the clinical efficacy of local delivery of nanoemulsion gel containing Centella asiatica extract as an adjunct to conventional non-surgical periodontal therapy in periodontitis…
- Trial name
- NCT07697209
- Testing
- Centella asiatica nanoemulsion gel, Scaling and Root Planing (SRP)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss
A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™
The aim of this study was to evaluate by histology and MSCT scans during a 7-month period, the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in the maintenance of alveolar ridge.
- Trial name
- NCT01105026
- Testing
- Alveolar Bone Defect Regeneration Following Tooth Extraction
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Atrophic Maxilla, Edentulous Jaw
Smart Box With OT Equator Attachment in Retaining Implant-assisted Overdenture for the Atrophic Maxilla.
The aim of the present study is to clinically and radiographically evaluate the effect of the use of recently developed Smart Box accompanied with OT Equator attachment in retaining of the inclined implant assisted overdenture…
- Trial name
- NCT05352620
- Testing
- Implant assisted maxillary overdenture
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Hams Hamed Abdelrahman
Periodontal Bone Loss
Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients
The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth.
- Trial name
- NCT02972788
- Testing
- Enamel Matrix Proteins Derivative, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Xenograft Model
Xenograft and Posterior Mandibular Socket Filling
The aim of this study is to evaluate the volume of madibular bone after placement of a xenograft in a fresh extraction socket in human.
- Trial name
- Flapless (NCT02736773)
- Testing
- xenograft material to slow resorption
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Alveolar Bone Loss, Bone Graft Failure
Ridge Preservation In Mandibular Molars Using Mixture Of ABB And Autogenous Particulate VS Sticky Bone
Histological Measurement Comparing the density of the new bone formed during socket preservation technique using a Mixture of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture of Injectable Platelets Rich Fibers…
- Conditions
- Alveolar Bone Loss, Bone Graft Failure, Alveolar Bone Resorption
- Trial name
- NCT03584997
- Testing
- ABB And Autogenous Particulate, PRF, ABB & Autogenous Particulate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apical Periodontitis
Sclerostin Regulation in Apical Periodontitis Lesions in Apical Periodontitis Lesions
Our aim was to examine the relationship between inflammatory bone resorption associated with the severity of AP and gingival crevicular fluid (GCF) and blood sclerostin and PGE2 levels in cases of AP.
- Trial name
- NCT06512103
- Testing
- Apical periodontitis group
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Alveolar Ridge Augmentation, Bone Substitutes
Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
The dimensional collapse of the alveolar ridge following tooth extraction represents a critical challenge for implant rehabilitation.
- Conditions
- Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Cone-Beam Computed Tomography
- Trial name
- NCT07879495
- Testing
- Alveolar Ridge Preservation using a synthetic alloplastic bone substitute and a resorbable polymer membrane, Minimally invasive flapless tooth extraction followed by unassisted spontaneous healing
- Volunteers
- 28 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Dental Implant, Tooth Extraction
Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques
The aim is to comparatively evaluate the soft tissue volume changes that occur after tooth extraction and immediate dental implant placement using two different surgical techniques.
- Conditions
- Dental Implant, Tooth Extraction, Bone Resorption
- Trial name
- NCT04803110
- Testing
- Dental implant placement after tooth extraction
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Aula Dental Avanzada
Crowding of Anterior Maxillary Teeth, Crowding of Anterior Mandibular Teeth
Comparing Labial and Lingual Orthodontic Appliances on Root Resorption and Bone Height
Patients who have moderate crowding that could be treated on a non-extraction will be treated in this study. The apical root resorption and alveolar bone height of the lingual and labial fixed appliances will be assessed.
- Trial name
- NCT06401369
- Testing
- Lingual brackets, Buccal brackets
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Alveolar Bone Loss
Comparison of Extra-short (4 mm) Implants Used as Distal Support of a Maxillary Full-arch Fixed Dental Prosthesis vs. 10 mm Implants Installed After Sinus Floor Elevation.
Recently, 4 mm long implants with a standard diameter have been used for the restoration of the posterior edentulous mandible with favorable results.
- Trial name
- NCT03958448
- Testing
- Placement of extra short implants, maxillary sinus lift, maxillary sinus elevation, maxillary sinus augmentation, placement of standard implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Hypoxia, Bone Resorption
Planetary Habitat Simulation: Bone Metabolism Studies
Bone losses are well known to occur in response to unloading (in microgravity or during immobilisation) and in patients with chronic obstructive airway disease (COPD).
- Trial name
- PlanHab (NCT02637921)
- Testing
- Hypoxia, Ambulatory, Normoxia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Bone Remodeling, Energy Metabolism
Retrospective Monocentric Evaluation of Biomarkers Associated With Bone, Muscle and Energy Metabolism
Bone is a metabolically active tissue undergoing continuous remodeling through the coordinated actions of osteoclasts (resorption), osteoblasts (formation), and osteocytes (regulation).
- Trial name
- OVAD (NCT07454252)
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Alveolar Bone Resorption, Sequela
Bone Material Comparison in Maxillary Sinus Augmentation
Hard and soft tissue deficiencies of an alveolar ridge arise as sequelae of tooth extraction when socket preservation is not applied.
- Conditions
- Alveolar Bone Resorption, Sequela, Tooth Extrusion
- Trial name
- NCT04433117
- Testing
- Shefabone, Bio-Oss
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohanad Al-Sabbagh
Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization
Graftless TSFE Via Self-tapping Implants
This prospective clinical trial aims to evaluate the efficiency, safety, and reliability of a minimally invasive graftless transcrestal sinus lifting approach with simultaneous dental implant placement in patients with edentulous…
- Conditions
- Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- G-TSFE (NCT07424742)
- Testing
- Graftless Transcrestal Sinus Membrane Elevation with Simultaneous Implant Placement
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Alveolar Process Atrophy
Ridge Preservation With Provisional Ovoid Pontic
A prospective randomized controlled trial of 30 patients from the Faculty of Dentistry of the UFJF was conducted. It was included patients who presented indication of extraction of premolars, canines or incisors.
- Trial name
- NCT03166475
- Testing
- Surgical procedures
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Alveolar Cleft
Partial Maxillary Expansion With Post Grafting Expansion vs. Pre Full Maxillary Expansion in Secondary Alveolar Cleft
Intermediate grafting with both pre- and post- grafting maxillary expansion with time span after grafting 6-8 weeks for consolidation and final retention for 3 months after finalization of expansion will get the advantages of…
- Trial name
- NCT05941988
- Testing
- pre grafting partial maxillary expansion with post grafting expansion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University