Clinical trials: Bone Turnover Markers
Osteoporosis, Frailty
Effects of DHEA/Exercise on Bone, Muscle and Balance
The purpose of this study is to examine whether muscle strength and balance will improve in women with frailty selected for dehydroepiandrosterone sulfate (DHEAS) levels below 550 ng/dl treated with DHEAS supplementation and…
- Trial name
- NCT00664053
- Testing
- DHEA, Yoga, Aerobics
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration (NASA)
Osteoporosis, Osteopenia
Investigating the Effect of Standardized Olive Extract on Bone Turnover Markers in Postmenopausal Women
The purpose of this study is to determine whether the intake of a daily dosage of standardized olive extract provides any protection against bone loss.
- Trial name
- NCT00789425
- Testing
- Standardized Extract of Olive Polyphenols
- Where
- Poland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- BioActor
Obesity
Relationships Between GLP-2 and Markers of Bone Turnover Following Feeding
This study has been designed to study differences bone turnover in relation to glucagon-like peptide-2 (GLP-2) following feeding in lean and obese premenopausal women.
- Trial name
- GLP-2 (NCT01531907)
- Testing
- Study visit procedures
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Osteopenia, Postmenopausal Osteopenia
Design and Development of a Novel Food Supplement for Osteoporosis Based on Gut Microbiome Mechanisms
It is well proven that the intestinal microbe regulates bone metabolism by the absorption of calcium and other metallic trace elements.
- Trial name
- OSTEOME (NCT05421819)
- Testing
- Calcium and vitamin D supplement, Calcium, vitamin D and prebiotic supplement, Calcium, vitamin D and flavonoid supplement
- Where
- Greece
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Lactation
Bone Accrual and Hormones in Response to Lactation
This is a prospective observational trial of healthy postpartum women to investigate changes in bone density and markers of bone turnover during lactation.
- Trial name
- NCT01563094
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Healthy
Effects of Pistachio Consumption on Body Composition and Blood and Bone Indicators
Research investigating beneficial effects of regular pistachio feedings on body composition (BC) and blood lipids are limited, and there are no studies that have investigated the effects of feeding pistachios on bone density or…
- Trial name
- CPsPistachio (NCT02849392)
- Testing
- Pistachio added 20% of kcals to diet
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California State Polytechnic University, Pomona
Calcium, Osteopenia
Effects of Amorphous Calcium Carbonate Supplementation on Bone Health in Postmenopausal Women With Osteopenia
This research was designed in accordance to the Method for Efficacy Assessment of Health Food for Bone Heath. Changes to bone density were measured to evaluate the effectiveness of amorphous calcium carbonate in maintaining bone…
- Conditions
- Calcium, Osteopenia, Bone Mineral Density, Bone Turnover Marker
- Trial name
- NCT05810909
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
Healthy Adults, High Altitude
Human Milk Oligosaccharides (HMOs) and Gut Microbiota, Immune System in Antarctica
Human milk oligosaccharides (HMOs) are the third-most abundant component in mothers' milk and are an important prebiotic factor for the development of the gut microbiota of infants, promoting the growth of certain beneficial…
- Conditions
- Healthy Adults, High Altitude, Isolation, Social
- Trial name
- NCT06133530
- Testing
- Human milk oligosaccharides, Maltose
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IU University of Applied Sciences
Type 1 Diabetes
Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes…
- Trial name
- NCT05892848
- Testing
- serum ostecalcin,serum sclerostin and parathroid profile
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hemodyalysis, Kidney Tansplant
Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients
This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general…
- Conditions
- Hemodyalysis, Kidney Tansplant, Osteoporosis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT07141043
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Bone Turnover Markers, Osteoporosis
Markers of Bone Turnover in Saliva and How This Compares to Urine and Blood
Study is being done to determine if it is possible to use saliva to measure bone specific proteins and predict bone turnover which could be used in the treatment of osteoporosis.
- Trial name
- NCT00323336
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoporosis
The Effectiveness of Eldecalcitol in the Bisphosphonate Non-respondered-patients With Osteoporosis
In the patients with osteoporosis, bisphosphonates (BPs) are a golden standard treatment. However, the bone turnover markers or the bone mineral density (BMD) are not improved in some osteoporotic patients even though they have…
- Trial name
- NCT02306187
- Testing
- Edirol
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
To Assess the Changes in Markers of Bone Turnover Over a Six Month Period After Epidural Steroid Inject, To Assess the Changes in Bone Mineral Density
Effect of Epidural Steroid Injection on Bone Mineral Density in Postmenopausal Women
To evaluate for the effect of corticosteroid epidural injections on bone mineral density in postmenopausal women. Candidates for the study: Post menopausal women between the ages of 55 and 80. No history of bone disease.
- Trial name
- NCT00941473
- Testing
- Triamcinilone (kenalog)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Bone Diseases, Osteomalacia
Study of the Diagnostic Value of Stable Calcium Isotope Profiling in Bone and Calcium Disorders
The purpose of this study is to determine whether mass spectrometry analysis of stable (non-radioactive) calcium isotopes in plasma or urine samples can help in the diagnosis of bone and calcium disorders.
- Conditions
- Bone Diseases, Osteomalacia, Osteoporosis
- Trial name
- eCaSIS (NCT02252679)
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hypovitaminosis D
A Study on Oral Vitamin D Megadoses
The purpose of this study is to determine if infrequent administration of oral vitamin D megadoses is effective treatment to maintain serum 25-hydroxyvitamin D(3) above target levels of 50-75 nmol/L.
- Trial name
- NCT01067898
- Testing
- vitamin D3 (cholecalciferol), olive oil, calcium carbonate
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital