Clinical trials: Borderline Personality Disorders
Family Caregivers
The Impact of a Psycho-educational Program for Family Members of Individuals With Borderline Personality Disorder
This is a prospective, single-arm, open-label study to assess the impact of the Family Connections (FC) program on various factors including burden, grief and several clinical variables (i.e., depressive symptoms, family…
- Trial name
- NCT06074289
- Testing
- Family connections program
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder
Quetiapine Treatment for Symptoms Associated With Borderline Personality Disorder
Objective: The objective of this study is to quantitatively examine the efficacy of Seroquel (active ingredient quetiapine fumarate) in subjects with Borderline Personality Disorder (BPD).
- Trial name
- NCT00122070
- Testing
- Quetiapine Fumarate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
Borderline Personality Disorder
Neural Mechanisms of Dialectical Behavioral Therapy in Patients with Borderline Personality Disorder
This research examines the behavioral and neural mechanisms of dialectical behavior therapy (DBT) effect in patients with borderline personality disorder (BPD).
- Trial name
- NeuroDBT (NCT06882330)
- Testing
- Dialectical behavior therapy
- Where
- Czechia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Masarykova Univerzita
Borderline Personality Disorder, Relatives
PEGASUS - Improving Treatment for Patients With Emotionally Unstable Personality Disorder
The purpose of the PEGASUS study is to conduct a pilot trial to test the feasibility and acceptability of the PEGASUS intervention, adding a case manager and family-based interventions meetings to the existing psychiatric…
- Trial name
- NCT06563466
- Testing
- The experimental intervention PEGASUS, Treatment as usual
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
SCHIZOPHRENIA 1 (Disorder), Borderline Personality Disorder
Disorders of the Sense of Self and Physical Activity
Schizophrenia (SZ) patients with metabolic syndrome, patients with vestibular syndrome, and patients with borderline personality disorder, would benefit from physical activity (PA).
- Conditions
- SCHIZOPHRENIA 1 (Disorder), Borderline Personality Disorder, Vestibular Syndromes
- Trial name
- sensdesoi (NCT06817980)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Borderline Personality Disorder
Screening of the Possible Risk Factors for Borderline Personality Disorders and Validation of Maclean Instrument
Borderline personality disorder is a mental illness that severely impacts a person's ability to regulate their emotions. This loss of emotional control can increase impulsivity, affect how a person feels about themselves, and…
- Trial name
- NCT05831852
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Borderline Personality Disorder
Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study
One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity.
- Trial name
- MASB (NCT04948905)
- Testing
- Evaluation using the Self-Defining Memory Questionnaire
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Personality Disorder, Borderline
Effectiveness Evaluation of 'The Endeavour Programme'
This study aims to evaluate the effectiveness of Dialectical Behaviour Therapy for adults with Borderline Personality Disorder attending Community Mental Health Services in Cork, Ireland.
- Trial name
- NCT03166579
- Testing
- Dialectical Behaviour Therapy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Health Service Executive, Ireland
Borderline Personality Disorder (BPD), Healthy Controls Group - Age and Sex-matched
Affect-based Impulsivity in Borderline Personality Disorder
The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old.
- Trial name
- NCT06880640
- Testing
- Stress Induction
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Borderline Personality Disorder
Five Factor Model Treatment for Borderline Personality Disorder
The primary purpose of this study is to explore acceptability, feasibility, and preliminary efficacy of a novel cognitive-behavioral treatment for borderline personality disorder (BPD).
- Trial name
- NCT04587518
- Testing
- Personality-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Borderline Personality Disorder
Biomarkers of Change in BPD After Metacognitive Interpersonal Therapy-standard Approach
The present randomised clinical trial aims to assess the clinical and neurobiological changes following Metacognitive Interpersonal Therapy -standard approach (MIT-SA) compared with Clinical Structured Treatment (CST) derived…
- Trial name
- CLIMAMITHE (NCT02370316)
- Testing
- Metacognitive Interpersonal Therapy (MIT-SA), Clinical Structured Treatment
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Self Harm, Suicide, Attempted
Emotional Dysregulation in Para-suicidal Behavior
This is a naturalistic cohort pre-post study investigating aspects of emotional processing and how possible changes in emotional processing is related to the successful treatment of non-suicidal self-injury and suicidal ideation…
- Conditions
- Self Harm, Suicide, Attempted, Emotional Instability, Borderline Personality Disorder
- Trial name
- NCT03846375
- Testing
- Psychotherapy, Pre-intervention testing
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Relatives
"Family Connections": a Program for Relatives of People With Borderline Personality Disorder
The aim of this study is to validate an intervention for relatives of people with borderline personality disorder in Spanish population in a randomized control trial.
- Trial name
- NCT04160871
- Testing
- Family Connections, Treatment As Usual
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Adolescent - Emotional Problem, Personality Disorders in Adolescence
Representations of the Body's Interior in Adolescence
Representations of the inner body in adolescence: developmental characteristics and specificities in borderline personality disorders.
- Conditions
- Adolescent - Emotional Problem, Personality Disorders in Adolescence, Body Representation, Borderline Personality Disorder
- Trial name
- RICA (NCT07407764)
- Testing
- Drawing of the inside of the body, interviews and questionnaires.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Borderline Personality Disorder, PTSD
Neural Correlates of Stress Hormones
To investigate which neuronal correlates underlie cortisol-induced enhancement of memory retrieval in PTSD and BPD.
- Trial name
- Cort-fMRI (NCT02523664)
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and BPD
The goal of PROSPER-B is to study effectiveness of EMDR compared to integrated DBT-EMDR in treatment-seeking, adult patients with comorbid PTSD and Borderline Personality Disorder (BPD).
- Trial name
- PROSPER-B (NCT03833453)
- Testing
- EMDR, DBT
- Where
- Netherlands
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Arkin
Borderline Personality Disorders, Avoidant Personality Disorders
Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions
Borderline Personality Disorder (BPD), a prevalent psychiatric disorder found in approximately 2% to 6% of the population and 20% of hospitalized psychiatric patients, has proven quite treatment resistant.
- Trial name
- NCT02465697
- Testing
- Reappraisal Training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Impulse Control Disorders, Borderline Personality Disorder
fMRI in Impulsivity
This study aims to use resting-state and task based functional Magnetic Resonance Imaging (fMRI) as a tool to evaluate trait characteristics of impulsivity in subjects with borderline personality disorder.
- Trial name
- NCT02755181
- Testing
- Experimental
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Personality Disorder, Borderline
Effectiveness of the Iconic Therapy for Borderline Personality Disorder Symptoms
Borderline personality disorder (BPD) is the most prevalent personality disorder in young community population whose most severe complication is suicide.
- Trial name
- NCT03011190
- Testing
- Emotional regulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Silvia Elisa Hurtado Santiago