Clinical trials: Botox
Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment
Efficacy of 200 IU OnabotulinumtoxinA in Idiopathic Overactive Bladder Resistant to Anticholinergic Treatment
This study aimed to assess the efficacy and safety of onabotulinumtoxinA (botulinum toxin type A) in patients with idiopathic overactive bladder (OAB) and urinary incontinence who had previously failed to respond to…
- Trial name
- NCT06408051
- Testing
- Injection of onabotulinumtoxinA into the bladder wall
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Gummy Smile Due to Hypermobile Upper Lip
Effect of Cross-linked Hyaluronic Acid Filler Versus Botulinum Toxin Type A (Botox) in Management of Gummy Smile
A smile is supposed to express one's feelings and expressions, for that there has been an awakening concern for the appearance of gummy smile. Gummy smile is the appearance of about 2mm or more of the gingiva during smiling.
- Trial name
- NCT06952218
- Testing
- Injection of cross linked hyaluronic acid filler
- Where
- 2 sites in Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myofacial Pain Syndrome, Botulinum Toxin
Botulinum Toxin A in Patients With Myofascial Pain Syndrome With and Without Zinc Supplementation
Research question: Dose the use of oral zinc supplement improve the effects of botulinum toxins injection in patients with myofascial pain dysfunction syndrome? Statement of the problem: MPDS Patients treated with botulinum toxin…
- Trial name
- NCT05605886
- Testing
- Solvazinc 50mg
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Forehead Rhytides, Forehead Wrinkles
Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment
The purpose of this study is to determine whether there is a difference in clinical effect, duration of effect, level of discomfort and patient satisfaction in patients receiving topical anesthesia on one side of the forehead and…
- Trial name
- NCT03799484
- Testing
- Botulinum toxin type A, 2.5% lidocaine/2.5% prilocaine, petrolatum ointment
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Glabellar Frown Lines
Split-Face Study Comparing Botox and Jeuveau in Treating Glabellar Lines
The purpose of this study is to compare the efficacy and side effects of Botox and Jeuveau for glabellar lines.
- Trial name
- NCT04715048
- Testing
- PrabotulinumtoxinA, Onabotulinum toxin A
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Spasticity
Retrospective Real-Life Study From One Brazilian Reference Center Assessing Long-Term Experience In The Treatment Of Adult Spasticity With AbobotulinumtoxinA
The aim of the study is to describe the long-term use of abobotulinumtoxinA (Dysport®) in adult subjects affected with upper limb spasticity (ULS) +/- lower limb spasticity (LLS) who received treatment with Dysport® for a minimum…
- Trial name
- RETURN (NCT04446702)
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ipsen
Vulvar Vestibulitis, Vulvar Diseases
Botox on Vulvar Vestibulitis
The study seeks to evaluate the effect of botulinum toxin on vulvar vestibulitis (VVS) after local injection with Botox, a potential treatment to relieve patients of vulvar pain, reducing the need for painkillers, and improving…
- Trial name
- NCT00119886
- Testing
- Botulinum toxin
- Where
- 2 sites in Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Vaginismus
Botox Injection for Treatment of Vaginismus
The use of Botox injections intravaginally and progressive dilation under anesthesia has been shown to cure vaginismus. This study expands the use of Botox injections to include progressive dilation, post procedure supervised…
- Trial name
- NCT01352546
- Testing
- BOTOX
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Plastic Surgery Professional Association
Patients with Jaw Muscles Myofascial Pain
A Comparative Study on the Impact of Trigger Points Injection of Platelet Rich Plasma Versus Botulinum Toxin on the Relief of Jaw Muscles Myofascial Pain
This study aims at comparing the effect of trigger points injection of platelet rich plasma and botulinum toxin a on the relief of jaw muscles Myofascial pain .
- Trial name
- NCT06814535
- Testing
- Botulinum Toxin A / Botulinum Toxin A, Platelet rich plasma
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mild to Moderate Temporal Atrophy, Moderate to Severe Glabellar Rhytids
Upper Facial Remodeling With Perlane-L and Dysport
The purpose of this study is to provide data to support combination treatment of the upper face with Perlane-L® and Dysport™. This study will assess the outcome of upper face rejuvenation in the temporal fossa; outcome of…
- Conditions
- Mild to Moderate Temporal Atrophy, Moderate to Severe Glabellar Rhytids, Moderate to Severe Periorbital Rhytids
- Trial name
- DPL-2010 (NCT01354743)
- Testing
- Dysport, Perlane L
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beer, Kenneth R., M.D., PA
Overactive Bladder, Overactive Bladder Syndrome
Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection
The goal of this clinical trial is to evaluate the outcomes of differing durations of antibiotic prophylaxis with bladder onabotulinumtoxinA injection in patients with refractory overactive bladder.
- Conditions
- Overactive Bladder, Overactive Bladder Syndrome, Urge Incontinence, Urinary Incontinence, Urge
- Trial name
- NCT05719285
- Testing
- Single-Dose Antibiotic, Multi-Dose Antibiotic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Rhytides
Spread of PrabotulinumtoxinA-xvfs Versus OnabotulinumtoxinA in the Treatment of Forehead Rhytides
Ten subjects will be enrolled in the study. Each subject will have their left and right forehead randomly assigned to receive 4 units of PrabotulinumtoxinA-xvfs or OnabotulinumtoxinA.
- Trial name
- NCT05807412
- Testing
- PrabotulinumtoxinA-Xvfs, OnabotulinumtoxinA
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lupo Center for Aesthetic and General Dermatology
Urinary Tract Infections
Comparison of Pre-procedural PCR and Culture-based UTI Assessment Prior to Intravesical Botox Injection
This study is a retrospective record review to determine whether a novel multiplex PCR assay can be utilized as a screening method for UTI in patients receiving Botox injection to treat overactive bladder (OAB).
- Trial name
- NCT04817865
- Testing
- Multiplex-PCR with Pooled Antibiotic Susceptibility Testing (M-PCR/P-AST), Urine Culture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pathnostics
Facial Flushing
Treatment of Facial Flushing With Botulinum Toxin A Injections
The purpose of this study is to find out if botulinum toxin A (botox®) can be used to treat facial flushing. This study is a pilot study designed to determine feasibility of these procedures.
- Trial name
- NCT02216838
- Testing
- botulinum toxin A, Saline Control
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Gingival Recession, Localized
Effect of Botulinum Toxin-A on Free Gingival Graft
The aim of this study was to examine the effects of Botulinum Toxin-A (BTX-A) injection to the mental muscle on the free gingival graft (FGG) operation.
- Trial name
- NCT05822323
- Testing
- BTX-A, free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kevser Sokmen
Excessive Gingival Display
EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients
The goal of this clinical trial is to compare the effect of EMG-guided Botox injection with conventional Botox injection in Yonsei point, in patients with excessive gingival display.
- Trial name
- NCT06075134
- Testing
- Botox injection, EMG, Zinc Supplement
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Direct Brow Lift, Scarring
Onabotulinum Toxin A in Direct Brow Lift
The brow lift is a surgical procedure that has been practiced for several decades. A typical indication is brow ptosis, which can be secondary to involutional changes or facial nerve palsies.
- Trial name
- NCT04383912
- Testing
- Botox Injectable Product
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Stress (Psychology), Stress
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
The purpose of this prospective single-center, blinded*, randomized, proof-of-concept study is to determine whether OnabotulinumtoxinA (BOTOX®) injections will change the level of stress perceived by generally healthy adult…
- Conditions
- Stress (Psychology), Stress, Healthy Adult Female Participants, Stress, Psychologic
- Trial name
- NCT06778421
- Testing
- Intramuscular injection, OnabotulinumtoxinA (Botox®) Injections, Sodium Chloride
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Center for Advanced Facial Plastic Surgery
Lateral Canthal Lines, Crow's Feet
Efficacy and Safety Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
The purpose of this study is to evaluate the safety and efficacy of 2 sequential doses of RT001 compared to placebo gel to treat moderate to severe lateral canthal lines in adults.
- Conditions
- Lateral Canthal Lines, Crow's Feet, Facial Wrinkles
- Trial name
- NCT00968942
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Revance Therapeutics, Inc.
Crow's Feet Lines
A Phase 1/3 Clinical Trial to Evaluate the Safety and Efficacy of HUTOX Compared to Botox® in Subjects With Moderate to Severe Crow's Feet Lines
A Phase 1/3 Clinical Trial to Evaluate the Safety and Efficacy of HUTOX Compared to Botox® in Subjects With Moderate to Severe Crow's Feet Lines
- Trial name
- NCT04081402
- Testing
- HU-014, Botox Inj
- Where
- South Korea
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.