Clinical trials: Botox
Migraine Disorders
A Study Using Botulinum Toxin Type A as Headache Prophylaxis in Adolescents With Chronic Migraine
To evaluate the efficacy and safety of Botulinum Toxin Type A versus placebo (normal saline) as headache prophylaxis in adolescents (children 12 to 17) with chronic migraine.
- Trial name
- NCT01662492
- Testing
- Botulinum toxin type A Dose 1, Botulinum toxin type A Dose 2
- Where
- 22 sites in United States
- Volunteers
- 125 people
- Sponsor
- Allergan
Rosacea, Botulinum Toxin
Clinical Observation of Botulinum Toxin A Treatment in the Treatment of Rosacea
the goal of this study is to study the clinical efficacy and safety of botox in the treatment of rosacea.
- Trial name
- NCT06282679
- Testing
- Botulinum Toxin Type A Injection [Botox]
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Sialorrhea, Amyotrophic Lateral Sclerosis
Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea
Evaluation of the decrease of the secretion of saliva in patients with amyotrophic lateral sclerosis by a local ultrasound-guided bilateral injection of botulinum toxin type A in parotids and submandibular glands.
- Trial name
- ALS-TOX (NCT01551940)
- Testing
- Botox injection
- Where
- 13 sites in France
- Volunteers
- 18 people
- Sponsor
- Hospices Civils de Lyon
Scar
Botox in the Healing of Surgical Wounds of the Neck
The investigators hypothesize that Botox A will reduce scarring and improve healing of surgical neck wounds.
- Trial name
- NCT01177358
- Testing
- Botulinum Toxin Type A, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Urinary Bladder, Overactive, Incontinence, Urge
Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A
Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in.
- Conditions
- Urinary Bladder, Overactive, Incontinence, Urge, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- NCT04305743
- Testing
- OnabotulinumtoxinA 100 UNT
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Ischemic Stroke, Hemorrhagic Stroke
Goal Attainment Scaling in Upper Limb Spasticity Treatment
Patients after stroke with upper limb spasticity treated with botulinum toxin-A (BTX-A) will be included in this two-part study.
- Trial name
- GASBTX (NCT04975646)
- Testing
- Prescribed exercise program
- Where
- Slovenia
- Volunteers
- 70 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Glabellar Frown Lines
Efficacy and Safety of a New Dilution and Injection Volume of AbobotulinumtoxinA for the Treatment of Glabellar Lines
An interventional phase 3 study to evaluate efficacy and safety of a new dilution and injection volume of AbobotulinumtoxinA treatment for glabellar lines
- Trial name
- NCT03960957
- Testing
- AbobotulinumtoxinA
- Where
- 11 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Raynaud's Disease
A Two-Part Study of BOTOX® Therapy for Ischemic Digits
Treating patients with Raynaud's phenomenon who have chronic pain and ulcerations is extremely challenging. Published reports and our previous work support our hypothesis that symptomatic patients experience relief of pain and…
- Trial name
- NCT01309802
- Testing
- onabotulinum toxin type-A
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Southern Illinois University
Hemiplegia and/or Hemiparesis Following Stroke
Exercise to Improve Sleep and Quality of Life in Stroke Patients Receiving Botulinum Toxin Treatment
This study aimed to investigate the contribution of aerobic exercise programmes to improving sleep quality, quality of life, and functional status, alongside conventional rehabilitation, in stroke patients who had received…
- Trial name
- NCT07369453
- Testing
- Aerobic exercise training using a cycle ergometer
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Migraine Disorders
A Study Using Botulinum Toxin Type A as Headache Prophylaxis for Migraine Patients With Frequent Headaches
This is a 60 week study including a double-blind phase followed by an open-label extension phase.
- Trial name
- NCT00156910
- Testing
- Botulinum Toxin Type A
- Where
- 2 sites in United States, Canada
- Volunteers
- 679 people
- Sponsor
- Allergan
Autonomic Dysreflexia
Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI
The purpose of this study is to investigate the impact of 200 U intradetrusor injected OnabotulinumtoxinA (Botox®, Allergan, Inc.) (20 sites, trigone sparing) for neurogenic detrusor overactivity (NDO) and its role on reducing…
- Trial name
- NCT02298660
- Testing
- BOTOX
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Rick Hansen Institute
Overactive Bladder
Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence
The purpose of this study is to assess the safety and effectiveness of botulinum toxin type A (onabotulinumtoxinA) in treating patients with idiopathic overactive bladder with urinary incontinence.
- Trial name
- NCT00910520
- Testing
- onabotulinumtoxinA, normal saline
- Where
- 7 sites in United States, Belgium and 5 more
- Volunteers
- 548 people
- Sponsor
- Allergan
Cervical Dystonia
Zinc as an Adjunctive Therapy for Cervical Dystonia
The goal of this clinical trial is to evaluate if supplemental zinc can prolong the duration of benefit of botulinum toxin injections in cervical dystonia patients receiving care at the University of Florida.
- Trial name
- NCT07140874
- Testing
- Zinc citrate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Plantar Fascitis, Botulinum Toxins, Type A
Therapeutic Effect of Botulinum Toxin A for the Treatment of Plantar Fasciitis.
Plantar fasciitis is the most common cause of plantar heel pain and is commonly present in people 40 years of age or older, overweight, sedentary or with intense physical activity.
- Trial name
- NCT03054610
- Testing
- Betamethason Sodium Phosphate, Ropivacaine, Botulinum Toxins, Type A
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Healthy
To Study the Peripheral Effect of Botulinum Toxin-A (Botox-A) on Experimentally Induced Cutaneous Pain in Healthy Subjects
This is a human trial to study the peripheral effect of therapeutic botulinum toxin (botox-A). The trial is performed on healthy normal males. The study comprises of two parallel placebo-controlled, double blinded studies.
- Trial name
- NCT00435682
- Testing
- Botox (Allergan Inc., US)
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aalborg University
Spasticity, Cerebral Palsy
Shockwaves Therapy and Botulinum Toxin for the Treatment of Spasticity in Patients With Cerebral Palsy. A Cross Over RCT
Spasticity is a motor disorder that can affect the lower limbs in up to 75% patients with cerebral palsy, having a significantly effect on their mobility and quality of life.
- Trial name
- NCT02400619
- Testing
- shock waves, Botulinum Toxin Type A
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Xavi Vidal Novellas
Bruxism
Botulinum Toxin-A for Bruxism Using Digital Occlusal Analysis
Bruxism is a repetitive jaw-muscle activity that may lead to tooth wear, muscle pain, headaches, and functional limitations. Current diagnostic approaches mainly rely on self-reported symptoms and clinical examination findings…
- Trial name
- NCT07640035
- Testing
- Botulinum Toxin-A injection
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Stroke, Spasticity, Muscle
Efficacy of Extracorporeal Shock Wave Therapy on Spasticity
Introduction: We aimed to compare the efficacy of Botulinum Toxin Type A(BoNT-A) injection and BoNT-A injection in combination with ESWT for post-stroke lower extremity ankle plantar flexor spasticity.
- Trial name
- NCT06225024
- Testing
- ESWT, BoNT A
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kayseri City Hospital
Subacromial Bursitis, Subdeltoid Bursitis
Ultrasound Guided Botulinum Toxin Type A Injection of Subacromial-Subdeltoid Bursa in Hemiplegic Shoulder Pain
Good shoulder function is a prerequisite for effective hand function, as well as for performing multiple tasks involving mobility, ambulation, and activities of daily living (ADL).
- Trial name
- NCT04467450
- Testing
- botulinum toxin type A, Methyl Prednisolonate
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Benha University
Tourette Syndrome, Chronic Vocal Tic
Pilot Study for Use of Dysport in Treatment of Vocal Tics in Patients With Tourette's Syndrome
Our intervention will be the injection of Abobotulinum toxin A into the affected site/vocal cords for patients with the diagnosis of Primary Tourette's syndrome.
- Trial name
- NCT02187679
- Testing
- Abobotulinum toxin A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Detroit Clinical Research Center
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