Clinical trials: Botulinum Toxin, Type A
Temporomandibular Disorder, Bruxism
Botulinum Toxin Administration on Masticatory Performance
This study aimed to evaluate the effect of botulinum toxin type A (BTX-A) injection on masticatory performance and nutritional status in temporomandibular disorder patients with bruxism caused by both intra-articular and…
- Trial name
- NCT05562531
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lateral Canthal Lines, Crow's Feet
Efficacy and Safety Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
The purpose of this study is to evaluate the safety and efficacy of 2 sequential doses of RT001 compared to placebo gel to treat moderate to severe lateral canthal lines in adults.
- Conditions
- Lateral Canthal Lines, Crow's Feet, Facial Wrinkles
- Trial name
- NCT00968942
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Revance Therapeutics, Inc.
Myofacial Pain Syndrome, Botulinum Toxin
Botulinum Toxin A in Patients With Myofascial Pain Syndrome With and Without Zinc Supplementation
Research question: Dose the use of oral zinc supplement improve the effects of botulinum toxins injection in patients with myofascial pain dysfunction syndrome? Statement of the problem: MPDS Patients treated with botulinum toxin…
- Trial name
- NCT05605886
- Testing
- Solvazinc 50mg
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gummy Smile Due to Hypermobile Upper Lip
Satisfaction Of Adult Patients With Gummy Smile Treated By Botulinum Toxin A Injection
The aim of the proposal study is to answer the question of how to manage gummy smiles due to hypermobile upper lip with less invasive and low risk level procedure .
- Trial name
- NCT03186547
- Testing
- Botulinum Toxin A Injection, Modified Lip Repositioning Surgery
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporo-Myofascial Disorder
Treatment of Temporo-Myofascial Disorder of Muscular Origin Using Botulinum Toxin: A Prospective Study
Temporomandibular disorders (TMD) are a group of conditions involving the temporomandibular joint (TMJ), masticatory muscles and associated structures.
- Trial name
- NCT02810015
- Testing
- Botulinum Toxin Type A
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sun-induced Wrinkles
Phase IV Study On Muscle Activity Of Two Commercial Preparations Of Botulinum
this study was proposed to provide more scientific and objective data on the clinical and aesthetic effects of these two toxins (Dysport and Xeomin).
- Trial name
- NCT01728337
- Testing
- Dysport, Xeomin
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Lateral Canthal Lines
Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
The purpose of this study is to evaluate the safety and efficacy of RT001 to treat moderate to severe lateral canthal lines in adults and duration of effect.
- Trial name
- NCT00907387
- Testing
- RT001
- Where
- 9 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Revance Therapeutics, Inc.
Smiling, Botulinum Toxins, Type A
Higher Doses of Botulinum Toxin in the Treatment of Gummy Smile
Botulinum type A (BTX-A) is an easy and efficacious treatment for gingival smile (GS). However, the necessary for higher-doses among patients are controversial.
- Trial name
- NCT05127018
- Testing
- injection of Botulinum type A
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Peking University
N/A, as no Specific Medical Condition Will be Treated
A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery Methods
The purpose of this study is to evaluate the distribution of IncobotulinumtoxinA (Xeomin) in healthy subjects at different volumes, concentrations and doses when administered intradermally and subcutaneously using different…
- Trial name
- NCT05585398
- Testing
- IncobotulinumtoxinA
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Scar
A Dosage-dependent Manner of Botulinum Toxin Type A on the Prevention of Postoperative Scars of Various Anatomic Regions of the Body
Each year, millions of burn, trauma, or surgical patients worldwide suffer from scarring that severely affects their quality of life and social functioning.
- Trial name
- NCT06349733
- Testing
- Botulinum toxin type A
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Crow's Feet Lines
A Phase 1/3 Clinical Trial to Evaluate the Safety and Efficacy of HUTOX Compared to Botox® in Subjects With Moderate to Severe Crow's Feet Lines
A Phase 1/3 Clinical Trial to Evaluate the Safety and Efficacy of HUTOX Compared to Botox® in Subjects With Moderate to Severe Crow's Feet Lines
- Trial name
- NCT04081402
- Testing
- HU-014, Botox Inj
- Where
- South Korea
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Wrinkle, Glabellar Frown Lines
Head-to-Head Comparison of All Botulinum Neurotoxin Type A Products for Glabellar Rhytides
Study Type: This is a multicenter, triple-blind, randomized controlled trial. Purpose: The goal of this clinical trial is to compare the effectiveness and safety of all commercially available Botulinum Neurotoxin Type A (BoNT-A)…
- Conditions
- Wrinkle, Glabellar Frown Lines, Glabellar Furrowing
- Trial name
- NCT06448676
- Testing
- Botulinum toxin type A
- Where
- 3 sites in Netherlands
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Aging
Evaluation of the Safety and Efficacy of OnabotulinumtoxinA to the Depressor Anguli Oris
Single Center, Double Blind, Placebo- Controlled Study of 20 subjects with 10 active drug/10 placebo Standardized baseline/pre-treatments and follow-up images will be taken.
- Trial name
- NCT04240535
- Testing
- OnabotulinumtoxinA 50 UNT [Botox Cosmetic]
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Amir Moradi MD, MBA
Gummy Smile
Effect of Clinical Crown Lengthening Surgery and Botulinum Toxin A Injection in Gummy Smile Treatment
Background: The demand for beauty is increasing in society as everyone is looking for cosmetic improvement, including gummy smile correction.
- Trial name
- NCT05057286
- Testing
- Clinical crown lengthening surgery
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Urinary Tract Infections
Comparison of Pre-procedural PCR and Culture-based UTI Assessment Prior to Intravesical Botox Injection
This study is a retrospective record review to determine whether a novel multiplex PCR assay can be utilized as a screening method for UTI in patients receiving Botox injection to treat overactive bladder (OAB).
- Trial name
- NCT04817865
- Testing
- Multiplex-PCR with Pooled Antibiotic Susceptibility Testing (M-PCR/P-AST), Urine Culture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pathnostics
Muscle Strength, Botulinum Toxins, Type A
Assessment of the Effect of Botulinum Toxin in Extensor Digitorum Brevis Via Strain Gauge and Nerve Conduction Studies
The purpose of this feasibility study is to determine if temporary weakness of a small foot muscle caused by local injection of botulinum toxin into that muscle can be measured with a strain gauge in addition to the previously…
- Trial name
- NCT00822523
- Testing
- Botulinum Toxin, Type A, Saline
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Pain, Face
Botox vs Occlusal Splint for Masseter Pain
This randomized clinical trial will compare the standard treatment (occlusal splint) and botox for the treatment of face muscular pain in adults.
- Trial name
- NCT03456154
- Testing
- Botox Injectable Product, Occlusal splint
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Hyperhidrosis
Hyperhydrosis Treatment Using Botulinum Toxin
The purpose of this study is to describe two safe and reproducible techniques for the treatment of hyperhidrosis using botulinum toxin.
- Trial name
- NCT03816046
- Testing
- botulinum toxin A
- Where
- Lebanon
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Post-operative Excessive Scarring
Botulinum Toxin is a Potential Prophylactic Therapy for Minimizing Post-excisional Scarring (Allergan Botox Scar Study)
Dermatological surgeons wear many hats to care for subjects with skin cancer. While their role in cancerous tissue removal results in superior cure rates, there is also a need for skilled excisional repair and effective wound…
- Trial name
- NCT02623829
- Testing
- Botulinum Toxin, Saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai