Clinical trials: Botulinum Toxin
Cerebral Palsy
Physical Therapy After Anti-spastic Treatment in Children With Cerebral Palsy
It is the primary purpose of this pilot study to investigate if physical therapy with strength training is better at improving muscle and gait function after anti-spastic treatment with Botulinum toxin compared to physical…
- Trial name
- NCT00552721
- Testing
- Physical therapy with strength training, Physical therapy without strength training
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Hvidovre University Hospital
Cerebral Palsy
Validity of Bispectral Index Monitoring During Deep Sedation
During Intramuscular botulinum toxin injections for children with cerebral palsy, immobility is essential to inject botulinum toxin to the right muscle.
- Trial name
- NCT02096549
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yeungnam University College of Medicine
Forehead Rhytides
A Study Comparing the Safety, Efficacy, and Diffusion of Letibotulinum Toxin A Versus Other Botulinum Toxin Products in Adults With Moderate-to-Severe Forehead Wrinkles
The goal of this clinical trial is to learn if letibotulinum toxin A is effective and safe for treating moderate-to-severe horizontal forehead wrinkles in adults.
- Trial name
- NCT07072806
- Testing
- Letibotulinum toxin A, Prabotulinum toxin A, Onabotulinum toxin A
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Torticollis
Effect of Botulinum Toxin Type A on Swallowing in Patients With Cervical Dystonia
The purpose of this study is to evaluate swallowing efficiency in patients with cervical dystonia following treatment with botulinum toxin Type A.
- Trial name
- NCT01384214
- Testing
- botulinum toxin Type A
- Where
- Croatia
- Volunteers
- 28 people
- Sponsor
- Allergan
Cerebral Palsy
Improvement on GMFCS Level of Patients With Cerebral Palsy Treated by Repeated Botulinum Toxin-A
The aim of this retrospective, monocenter, observational study is to evaluate the changes in GMFCS levels of children with cerebral palsy (CP) who received repeated Botulinum Toxin-A (BoNT-A) injections in the lower limb(s) with…
- Trial name
- NCT03344952
- Testing
- Botulinum toxin type A, Physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 503 people
- Sponsor
- Kocaeli University
Migraine Without Aura Prophylaxis
Dysport® In Migraine Without Aura Prophylaxis : DIMWAP Study
The purpose of this study is to determine whether 120 Unit, and 240 unit of botulinum toxin A are effective in the treatment of migraine without aura prophylaxis.
- Trial name
- NCT00258609
- Testing
- Botulinum Toxin type A (Dysport ® ) IM/SC 6-sites pericranial injection
- Where
- 6 sites in Thailand
- Volunteers
- 128 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Chronic Migraine, Chronic Migraine, Headache
Efficacy of Nerve Block Versus Botox in Chronic Migraine Management
The goal of this clinical trial is to determine whether nerve block injections (specifically, supratrochlear and greater occipital nerve injections) are as effective as Botulinum toxin A (Botox) injections in treating chronic…
- Trial name
- NCT06684249
- Testing
- Nerve Block Injections, Botulinum Toxin A
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Zagazig University
Hyperhidrosis
A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis
This is a three year open-label study in subjects with axillary hyperhidrosis.
- Trial name
- NCT00168480
- Testing
- Botulinum Toxin Type A
- Where
- 4 sites in United States, Germany and 2 more
- Volunteers
- 424 people
- Sponsor
- Allergan
Blepharospasm
Comparison of Korean Botulinum Toxin Type A Versus Botox in the Treatment of Essential Blepharospasm
To compare the efficacy and safety of Korean botulinum toxin A (KbtxA, Pacific Pharmaceuticals, Korea) against Botox in the treatment of essential blepharospasm, we performed a double-blinded, randomized, comparative trial…
- Trial name
- NCT00682760
- Testing
- Korean Botulinum toxin type A (KbtxA) and Botox injection
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Pacific Pharmaceuticals
Facial Scars
Botulinum Toxin and Mesotherapy on Enhancement of Facial Scarring
Most of the body's tissues can undergo wound repair following a disruption of tissue integrity. Upon healing, these wounds result in scar formation. The scars widen when the overlying musculature pulls apart suture lines.
- Trial name
- NCT06562023
- Testing
- Botulinum Toxin Type A, Mesotherapy
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Hams Hamed Abdelrahman
Unilateral Cleft Lip
Botulinum Toxin Injection in Reducing Scar Following Cheilorrhaphy.
the aim of the study will be directed to evaluate clinically the effect of botulinum toxin type A injection on reducing the scar following cleft lip surgical repair.
- Trial name
- NCT07137234
- Testing
- Modified Millard rotation advancement flap technique, botulinum toxin injection (BTX A) before surgical intervention
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
Thrombosed External Hemorrhoid
Pain Relief for Thrombosed External Haemorrhoids
Thrombosed external haemorrhoids are one of the most frequent anorectal emergencies. They are associated with swelling and intense pain.
- Trial name
- NCT00717782
- Testing
- injection of botulinum toxin, injection of saline
- Volunteers
- 30 people
- Sponsor
- University of Palermo
Overactive Bladder
Comparative Efficacy and Safety if Intravesical Botulinum Toxin A Versus Platelet-Rich Plasma in the Management of Refractory Overactive Bladder : A 2 Year Study
The goal of this clinical trial is to compare the efficacy and safety of intravesical Botulinum Toxin A versus intravesical Platelet-Rich Plasma (PRP) in adults with refractory overactive bladder who have not responded adequately…
- Trial name
- NCT07693192
- Testing
- Intravesical Botulinum Toxin A (100U), Intravesical Platelet-Rich Plasma
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mahmoud Mohamed Farag Ali
Carpometacarpal Sprain, Thumb Sprain
Injection of Botulinum Toxin for Thumb Carpometacarpal Arthritis
The purpose of this clinical trial is to gather information on the safety and effectiveness of botulinum toxin injection (or Botox) in the treatment of thumb joint pain/arthritis.
- Conditions
- Carpometacarpal Sprain, Thumb Sprain, Clostridium; Botulinum
- Trial name
- NCT05990881
- Testing
- Botulinum toxin, Standard-of-care corticosteroid injections
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rhode Island Hospital
Bruxism, Occlusal Changes
Vertical Facial Morphology and Occlusal Force Changes After Masseter Botulinum Toxin Injection in Bruxism
This study investigated whether the shape of the face affects how jaw muscles respond to botulinum toxin injections in people who grind their teeth (bruxism).
- Trial name
- NCT07673471
- Testing
- Botulinum Toxin Type A (BOTOX) Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Biruni University
Lateral Canthus Rhytides, Crow's Feet Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines
This study will evaluate the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of Crow's Feet Lines (Lateral Canthal Rhytides).
- Trial name
- NCT01189747
- Testing
- onabotulinumtoxinA, normal saline
- Where
- 4 sites in United States, Belgium and 2 more
- Volunteers
- 446 people
- Sponsor
- Allergan
Cervical Dystonia
Study Comparing Short Term Efficacy of Dysport and Dysport NG to Placebo, and to Assess Efficacy and Safety of Dysport NG of Subjects With Cervical Dystonia
The purpose of this study is to evaluate how well a new drug called Dysport NG works and how safe it is, when it is used for the treatment of cervical dystonia. Dysport NG will be compared to an approved drug called Dysport.
- Trial name
- NCT01261611
- Testing
- Botulinum toxin type A
- Where
- 57 sites in Australia, Austria and 9 more
- Volunteers
- 382 people
- Sponsor
- Ipsen
Graves Ophthalmopathy
Use of Botox in the Management of Thyroid Related Upper Eyelid Retraction
Currently there are few therapeutic options for the treatment of lid retraction secondary to thyroid orbitopathy (TO) during the active stages of the disease.
- Trial name
- NCT01272414
- Testing
- Botulinum Toxin Type A, Saline injection
- Where
- Canada
- Sponsor
- University of Toronto
Esophageal Achalasia
Randomized Study of Botulinum Toxin Type A for Achalasia
OBJECTIVES: I. Compare the efficacy of two doses of botulinum toxin in the treatment of achalasia. II. Compare the safety of these two doses in these patients.
- Trial name
- NCT00004416
- Testing
- botulinum toxin type A
- Volunteers
- 56 people
- Sponsor
- University of Texas
TMD/Orofacial Pain, Myalgia of Mastication Muscle
Botulinum Toxin in the Management of Temporo-mandibular Related Myalgia: a Prospective Study
The aim of this study was to evaluate the clinical course in terms of pain, function and quality of life of patients with TMD-related myalgia during six months after receiving BTX-A injections.
- Conditions
- TMD/Orofacial Pain, Myalgia of Mastication Muscle, Botulinum Toxin, Type a
- Trial name
- BOMAMY (NCT06677216)
- Testing
- Botulinum Toxin, Type A
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Diakonessenhuis, Utrecht