Clinical trials: Bowel Dysfunction, open to volunteers
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis
Sacral Neuromodulation for Neurogenic Lower Urinary Tract, Bowel and Sexual Dysfunction
A multi-center double-blinded placebo-controlled randomized clinical trial. The patients will be randomized into two groups. To investigate the efficacy of SNM to improve the key bladder diary variables compared to placebo (i.e.
- Conditions
- Neurogenic Dysfunction of the Urinary Bladder, Multiple Sclerosis, Sacral Neuromodulation, Bowel Dysfunction
- Trial name
- NCT05380856
- Testing
- Turning ON the neuromodulator, Turning OFF the neuromodulator
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Bowel Dysfunction, Dysmotility
Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children
The goal of this clinical trial is to learn if the new non-invasive device (Body Surface Colonic Mapping) works to accurately assess colonic movement and function in children.The main questions it aims to answer are: Are Body…
- Conditions
- Bowel Dysfunction, Dysmotility, Hirschsprung Disease, Anorectal Malformations
- Trial name
- NCT07789782
- Testing
- Body Surface Colonic Mapping
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Murdoch Childrens Research Institute
Neurogenic Bowel Dysfunction, Spinal Cord Injury
Vibrant Capsule for Spinal Cord Injury Neurogenic Bowel Dysfunction
The goal of this study is to test the safety and effectiveness of Vibrant capsules in spinal cord injury patients with neurogenic bowel.
- Trial name
- NCT07213986
- Testing
- Vibrant Capsule
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity
Liver Steatosis and Fibrosis in Non-Celiac Wheat Sensitivity Patients: a Prospective Study
Hypothesizing an intestinal barrier impairment as a common pathophysiological substrate of both Non Celiac Wheat Sensitivity (NCWS) and Metabolic Dysfunction-Associated Steatotic Liver Disease (MAFLD), in a retrospective cohort…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity, Irritable Bowel Syndrome, Functional Dyspepsia
- Trial name
- NCT07750535
- Testing
- Prevalence and severity of liver steatosis and fibrosis,
- Where
- 2 sites in Italy
- Volunteers
- 250 people
- Sponsor
- University of Palermo
Bladder-Bowel Dysfunction, Obesity & Overweight
Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel.
- Trial name
- OBE-BBD (NCT07724158)
- Testing
- Target physiotherapy, Exercise support intervention, Usual obesity care
- Where
- Portugal
- Volunteers
- 237 people
- Sponsor
- University of Lisbon
Neurogenic Bowel Dysfunction, Spinal Cord Injury
Kinesio Taping for Neurogenic Bowel Dysfunction in Spinal Cord Injury
Neurogenic bowel dysfunction is a common complication of spinal cord injury and may cause constipation, difficulty with defecation, prolonged bowel care, incomplete evacuation, fecal incontinence, and reduced quality of life.
- Trial name
- NCT07705984
- Testing
- Kinesio Taping, Routine Bowel Management Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Inflammatory Bowel Diseases, Crohn Disease
Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Indeterminate Colitis
- Trial name
- STRIDE (NCT06315179)
- Testing
- Esophagogastroduodenoscopy (EGD) with biopsy, Colonoscopy w/ biopsy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Neurogenic Bowel Dysfunction
Stimulation for Bowel Emptying
The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which…
- Trial name
- NCT06078176
- Testing
- Electrical Rectal Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- VA Office of Research and Development
Bladder and Bowel Dysfunction
Peppermint Oil as a Treatment for Children With Bladder and Bowel Dysfunction
The goal of this clinical trial is to study the effect of peppermint oil in in children with bladder and bowel dysfunction. The main question it aims to answer is: Does peppermint oil improve symptoms of bladder and bowel…
- Trial name
- NCT05613153
- Testing
- Peppermint Oil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Orange County
Bladder and Bowel Dysfunction, SCI - Spinal Cord Injury
SCS Therapy for Patients With Bladder and Bowel Dysfunction After SCI
This clinical trial aims to evaluate the safety and efficacy of spinal cord stimulation (SCS) in treating patients with urinary and bowel dysfunction after spinal cord injury (SCI).
- Trial name
- SCSBBD (NCT07511244)
- Testing
- Spinal Cord Stimulation and Evaluation
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Spinal Cord Injuries, Bowel Dysfunction
Noninvasive Spinal Cord Stimulation for Early SCI
The investigators are looking to determine the safety and efficacy of non-invasive transcutaneous spinal cord stimulation (TSCS) in promoting recovery of lower urinary tract (LUT), bowel, sexual, and cardiovascular function, as…
- Conditions
- Spinal Cord Injuries, Bowel Dysfunction, Sexual Dysfunction, Autonomic Dysfunction
- Trial name
- NCT06587841
- Testing
- Spinal COrd NEuromodulation™ (SCONE™) for transcutaneous spinal cord stimulation (TSCS)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Spinal Cord Injury, Neurogenic Bowel Dysfunction
Artificial Int: Neurogenic Bowel Education in Spinal Cord Injury Patients
The aim of this study is to evaluate the effectiveness of patient education delivered through an artificial intelligence (AI)-based mobile application in the management of neurogenic bowel dysfunction in individuals with spinal…
- Trial name
- ArtInt (NCT07369349)
- Testing
- Mobil Application
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Senem Duman
Spinal Cord Injury, Autonomic Dysfunction
Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury
This study is a pilot clinical trial to explore the efficacy of transcutaneous spinal cord stimulation (TCSCS) (proof-of-concept) in mitigating crucial autonomic dysfunctions that impact the health-related quality of life of…
- Conditions
- Spinal Cord Injury, Autonomic Dysfunction, Sexual Dysfunction, Neurogenic Bladder Dysfunction
- Trial name
- NCT05369520
- Testing
- TESCoN or SCONE device - Thoracic stimulation, TESCoN or SCONE device - Lumbosacral stimulation
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Inflammatory Bowel Disease (IBD), Metabolic Dysfunction Associated Fatty Liver Disease
An Observational Study of Inflammatory Bowel Disease (IBD) Patients With Non-alcoholic Fatty Liver Disease (NAFLD)
Inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease, are currently of unknown etiology and incurable.
- Trial name
- NCT06939569
- Where
- China
- Volunteers
- 337 people
- Sponsor
- Shanghai East Hospital
Post Operative Analgesia, Opioid Consumption, Postoperative
Intravenous Acetaminophen to Reduce Post-operative Opioid Consumption
Acetaminophen (Tylenol) is a commonly used medication after surgery to control pain. Tablets for oral use and suppositories for rectal use are the most frequently employed forms of acetaminophen after surgery.
- Conditions
- Post Operative Analgesia, Opioid Consumption, Postoperative, Acetaminophen, Abdominal Surgeries
- Trial name
- ACETAPOP (NCT06923540)
- Testing
- IV Acetaminophen
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Bowel Dysfunction, Colon Disease
Enteral Feeding of Fibre to Improve Microbiota
Following surgical removal of diseased bowel, patients often require a temporary redirection of bowel contents to a stoma, to allow healing prior to re-joining of the remaining bowel at a later date.
- Conditions
- Bowel Dysfunction, Colon Disease, Ileum--Diseases
- Trial name
- NCT06288464
- Testing
- Soluble Fibre
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Gynecologic Cancers, Breast Cancer Female
Pelvic Health Rehabilitation After Breast and Gynecologic Cancer
The GYVE study aims at testing an online program (eModule) to help people who have had breast or gynecologic cancer and are experiencing pelvic health issues like urinary incontinence and pain during sex.
- Conditions
- Gynecologic Cancers, Breast Cancer Female, Incontinence, Incontinence Bowel
- Trial name
- GYVE (NCT06822582)
- Testing
- Pelvic Health Module
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Laval University
Irritable Bowel Syndrome, Erectile Dysfunction
Elliptical Physical Activity and Sexual Dysfunction in Males With Irritable Bowel Syndrome
psychological disturbances resulting from irritable bowel syndrome causes sexual dysfunction in men such as weak erection of penis.
- Trial name
- NCT06783894
- Testing
- exercise (elliptical training)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Autoimmune Diseases, Epilepsy
VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems
Vagal nerve stimulation is a neurosurgical procedure consisting of implantation of an impulse generator battery with leads placed into the vagus nerve in the neck.
- Conditions
- Autoimmune Diseases, Epilepsy, Autonomic Dysfunction, Inflammatory Bowel Diseases
- Trial name
- VNS-IG (NCT03953768)
- Testing
- Vagal nerve stimulation (VNS)
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Louisville