Clinical trials: Bowel Functions
Irritable Bowel Syndrome (IBS)
Diet and Motility in IBS
The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help…
- Trial name
- IBS (NCT07283341)
- Testing
- Wireless Patch System
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Irritable Bowel Syndrome
Internet-delivered CBT for Irritable Bowel Syndrome
The aim of this study is to investigate the efficacy of a 10 week Internet-delivered CBT treatment for patients diagnosed with IBS. The patients' work with the treatment and is supported through online contact with a therapist.
- Trial name
- NCT01171053
- Testing
- Internet-delivered CBT, Therapist support
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Karolinska Institutet
Ileostomy - Stoma, Rectal Cancer
Early Ileostomy Closure for Rectal Cancer Patients in North America
Our preliminary work demonstrates that there is buy-in from both patients and surgeons with regards to early ileostomy closure (EIC) for select rectal cancer patients undergoing restorative proctectomy (RP) and diverting loop…
- Trial name
- NCT05027737
- Testing
- Early Ileostomy Closure
- Where
- 4 sites in Canada
- Volunteers
- 118 people
- Sponsor
- Jewish General Hospital
Colorectal Cancer
Function and Quality of Life After Emergency vs Planned Creation of a Stoma
The aim is to compare functional outcome and or quality of life in patients with a stoma that was constructed as an emergency procedure with patients where a stoma was created as a planned procedure.
- Trial name
- StomaFUNQ (NCT05102981)
- Testing
- emergency procedure
- Where
- Sweden
- Volunteers
- 700 people
- Sponsor
- Eva Haglind, MD, PhD, professor
Colon Cancer, Inflammatory Bowel Diseases
Local Anesthetic Wound Infusion and Functional Recovery After Colon Surgery
This is a double blinded randomized controlled trial in patients undergoing colon open surgery. The purpose is to evaluate the effectiveness of two different analgesic techniques on functional recovery after surgery.
- Conditions
- Colon Cancer, Inflammatory Bowel Diseases, Diverticulitis
- Trial name
- NCT01062919
- Testing
- Epidural analgesia, Wound catheter
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Franco Carli
Irritable Bowel Syndrome, Diet Modification
Efficacy of Low-FODMAPs Dietary Therapy for Irritable Bowel Syndrome in China
The primary aim of our study is to carry out a randomized trial to evaluate the efficacy of low-FODMAPs dietary therapy compared to conventional therapy for IBS patients recruited from tertiary hospitals in China.
- Trial name
- NCT03304041
- Testing
- low-FODMAPs diet, Traditional dietary advice
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Sir Run Run Shaw Hospital
Ulcerative Colitis, Inflammatory Bowel Diseases
Comparison of Functional Outcomes Between Transanal and Laparoscopic vs Open Ileal Pouch-Anal Anastomosis
Background: Ulcerative colitis (UC) and inflammatory bowel unclassified (IBDu) are inflammatory bowel diseases (IBD) involving the colon and rectum.
- Conditions
- Ulcerative Colitis, Inflammatory Bowel Diseases, Ileal Pouch
- Trial name
- FUNCTIon (NCT04722757)
- Testing
- ta-IPAA, tabd-IPAA
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Mount Sinai Hospital, Canada
Acupuncture-like Transcutaneous Electrical Nerve Stimulation, Irritable Bowel Syndrome
Acupuncture-like Transcutaneous Electrical Nerve Stimulation on Bowel Symptom and Quality of Life in Patients With Irritable Bowel Syndrome
To discuss the effects of improving the irritable bowel syndrome patients' quality of life and defecation after implementing acupuncture-like Transcutaneous Electrical nerve stimulation.
- Trial name
- NCT05042661
- Testing
- acupuncture-like transcutaneous electrical nerve stimulation
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Irritable Bowel Syndrome, Diarrhea
Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?
Our hypothesis is that the medication approved for treatment of high blood cholesterol levels, Colesevelam HCl (WELCHOL), decreases colonic transit and permeability in patients with diarrhea due to irritable bowel syndrome.
- Trial name
- welchol (NCT00911612)
- Testing
- Colesevelam
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Congenital Disorders
Racial Distribution of Heterotaxy Syndrome
Heterotaxy syndrome is a heterogeneous disease that is the result of a failure of normal right-left lateralization of the abdominal and thoracic organs during development.
- Trial name
- NCT00485654
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Children's Healthcare of Atlanta
Intestinal C. Difficile
Probiotic Intervention With Elderly Subjects
The study objective is to evaluate the effect of probiotic on faecal Clostridium difficile levels of elderly subjects.
- Trial name
- NCT01475942
- Testing
- Probiotic
- Where
- Finland
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Danisco
Functional Dyspepsia
Probiotic and Ginger Supplement for Symptoms and Quality of Life in Functional Dyspepsia (SUBTILE)
Functional dyspepsia (FD) is a frequent functional gastrointestinal disorder characterized by bothersome postprandial fullness, early satiety, epigastric pain, or burning, in the absence of any structural or metabolic cause.
- Trial name
- SUBTILE (NCT07212907)
- Testing
- Symbiosys® Stomalex (commercial name)
- Where
- 2 sites in France
- Volunteers
- 198 people
- Sponsor
- Biocodex
IBD - Inflammatory Bowel Disease, IBS - Irritable Bowel Syndrome
Low FODMAP Diet on Nutritional Status, Disease Activity and Gut Microbiota in IBS and UC With Normal or Overweight BMI
Gastrointestinal disorders represents 20-50% of referrals to the gastroenterologist; being the most affected womens, youths and older adults.
- Conditions
- IBD - Inflammatory Bowel Disease, IBS - Irritable Bowel Syndrome, UC - Ulcerative Colitis
- Trial name
- NCT04143633
- Testing
- Low FODMAP diet, Standard diet
- Where
- Mexico
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexico
Healthy, Healthy Nutrition
The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial
The goal of The BEGIN Study, a randomized controlled double-blinded intervention trial, is to learn if probiotics, with Bifidobacterium longum subspecies infantis Bifin02 (B.
- Trial name
- BEGIN (NCT06452199)
- Testing
- B. infantis
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Rectal Cancer
Intraoperative Monitoring of the Pelvic Autonomic Nerves
One of the major problems of rectal cancer surgery is pelvic autonomic nerve damage, which is the main cause of urogenital dysfunction influencing postoperative quality of life.
- Trial name
- NEUROS (NCT01585727)
- Testing
- TME, Neuromonitoring
- Where
- Germany
- Volunteers
- 188 people
- Sponsor
- Johannes Gutenberg University Mainz
Obesity, Food Preferences
How Altered Gut-Brain-Axis Influences Food Choices: Part 1
Obesity is currently one of the most substantial health burdens. Due to the production of marked and sustained weight loss, bariatric surgery is an increasingly used therapeutic modality to combat obesity and its comorbidities.
- Trial name
- BrainFood (NCT04813003)
- Testing
- Functional Brain Imaging and neurobehavioural tasks
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lia Bally
Irritable Bowel Syndrome
Reliability of a Food Frequency Questionnaire in the Assessment of Dietary Intake Including FODMAPs in Different Populations, and Relationship With IBS Symptoms and the Degree of Self-assessed Physical Activity
During an online assessment participants will fill in questionnaires evaluating demographic data, psychological variables, the degree of self-assessed physical activity and symptoms of irritable bowel.
- Trial name
- NCT05293769
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 400 people
- Sponsor
- Universitair Ziekenhuis Brussel
Irritable Bowel Syndrome
Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome
This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.
- Trial name
- NCT02179905
- Where
- Taiwan
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
IBS - Irritable Bowel Syndrome
Postprandial Lipids in IBS and Nutritional Treatment
Irritable Bowel Syndrome (IBS) is a disease that affects a large number of people. Adequate treatment is difficult, partially due to the heterogeneity of the patients and the complicated pathology in which not all mechanisms are…
- Trial name
- PLINT (NCT05016596)
- Testing
- turmeric
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Irritable Bowel Syndrome (IBS)
Mindfulness Training Versus Low (FODMAP) Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols Diet
The study aims to compare the effect of mindfulness-based awareness training in Irritable Bowel Syndrome (IBS) (MB-IBS-EAT) with the dietary standard of care (low fermentable oligosaccharides, disaccharides, monosaccharides and…
- Trial name
- FODMAP (NCT05630703)
- Testing
- Mindfulness-based Attention Training in IBS, Low FODMAP Diet
- Sponsor
- Wake Forest University Health Sciences
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