Clinical trials: Bowel Habits
NAFLD, Fecal Microbiota
Dietary Counseling Coupled With FMT in the Treatment of Obesity and NAFLD - the DIFTOB Study
There are several studies performed to reveal the linkage between diet, fecal microbiota, and obesity. Human fecal microbiota transplantations in this asset are still scarce.
- Conditions
- NAFLD, Fecal Microbiota, Gut Microbiota, Obesity
- Trial name
- DIFTOB (NCT05607745)
- Where
- 3 sites in Finland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Spinal Cord Injury, Neurogenic Bladder
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation. The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel…
- Conditions
- Spinal Cord Injury, Neurogenic Bladder, Incontinence
- Trial name
- NCT02978638
- Testing
- Finetech Vocare Bladder System
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Palo Alto Veterans Institute for Research
Obstructed Defecation Syndrome (ODS)
Stapled TransAnal Rectal Resection (STARR): Clinical and Radiological Outcome
To evaluate the correlation between clinical and radiological outcome after Stapled TransAnal Rectal Resection (STARR)
- Trial name
- NCT00587080
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Constipation
The Effects of Abdominal Massage on Functional (Primary) Chronic Constipation
The aim of the present study is to investigate the efficacy of abdominal massage in patients with functional (primary) chronic constipation. The present study is designed as a randomized placebo controlled.
- Trial name
- NCT03764995
- Testing
- Standard bowel management, Abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Hacettepe University
Rectal Prolapse, Rectocele
Long Term Results of STARR With Contour Transtar
Obstructed defecation syndrome (ODS) is a widespread and disabling syndrome. With this study the investigators want to evaluate the long term results of Stapled Transanal Rectal Resection (STARR) performed with Contour Transtar…
- Conditions
- Rectal Prolapse, Rectocele, Intussusception of Rectum
- Trial name
- LTSTARR (NCT02971332)
- Testing
- Stapled Transanal Rectal Resection
- Volunteers
- 113 people
- Sponsor
- University of Roma La Sapienza
Obstructed Defaecation Syndrome, Anterior Rectocele
Rectocele Repair with or Without Internal Sphincter Botulinum Toxin Injection: a Prospective Randomized Trial
This is a single-centre, prospective randomized controlled trial on female patients with anterior rectocele associated with obstructed defecation syndrome
- Trial name
- NCT06804993
- Testing
- Transvaginal repair & botulinum toxin type A injection, Transvaginal repair & distilled water injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
IBS-C and IBS With Mixed Bowel Habits
Efficacy of Tegaserod in Relieving the Symptoms of Female Patients With Irritable Bowel Syndrome (IBS), Excluding Those With Predominant Diarrhea IBS
Recent literature has demonstrated that the group of IBS sufferers who experience mixed bowel habits may be more similar to IBS-C patients than IBS-D patients.
- Trial name
- NCT00142987
- Testing
- Tegaserod
- Volunteers
- 664 people
- Sponsor
- Novartis
Colorectal Cancer
Determining Energy Needs in Colorectal Cancer
This is an observational study to assess the determinants of energy expenditure in cancer, and how those change throughout the disease trajectory.
- Trial name
- RECODE (NCT03131921)
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Constipation
Effect of L. Reuteri on Bowel Movements in Children (BIOWELL Study)
A randomized, multicenter, placebo-controlled, double blind study in two parallel groups testing the efficacy of daily oral supplementation with the probiotic L.reuteri DSM17938 compared to placebo in increasing the number of…
- Trial name
- BIOWELL (NCT03030664)
- Testing
- L.reuteri
- Where
- 5 sites in France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Surgery, Obstructive Defecation Syndrome
Mental Health Outcome After Surgery for Obstructed Defecation Syndrome (ODS)
Background: Obstructed Defecation Synsdrome (ODS) causes people to strain and sometimes need help to go to the toilet. They think about going to the toilet a lot, which makes their lives worse.
- Conditions
- Surgery, Obstructive Defecation Syndrome, Mental Health Issue, Depression/Anxiety
- Trial name
- MentODSSurg (NCT06502184)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Gut Microbiome, Neurocognitive Correlates of Eating Habits
Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants
The goal of this clinical trial is to learn if daily avocado intake can improve growth and brain and gut health in infants. The main questions it aims to answer are: Does daily eating of avocados change which microbes live in the…
- Conditions
- Gut Microbiome, Neurocognitive Correlates of Eating Habits, Infant Growth
- Trial name
- Guac & Grow (NCT06876935)
- Testing
- Daily avocado
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Hysterectomy, Myomectomy
Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery
Postoperative pain continues to be inadequately managed and is the most common reason for the delay in discharge and unplanned hospital admission after surgery. Opioids remain the mainstay for postoperative analgesia.
- Trial name
- NCT03363425
- Testing
- Lidocaine Iv, Dexmedetomidine, Normal saline
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Gastroschisis
Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis
Gastroschisis is a congenital defect of the abdominal wall that leads to evisceration of various amounts of the abdominal organs.
- Trial name
- NCT03355326
- Testing
- Glycerin Suppository
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gastrointestinal Problem, Anxiety
Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function
This study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures.
- Conditions
- Gastrointestinal Problem, Anxiety, Stress, Gastrointestinal Symptoms
- Trial name
- Tetrasol (NCT06425094)
- Testing
- Microalgae Extract Capsules
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Obstructed Defaecation Syndrome
Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic Patients
Obstructed defaecation syndrome is a common problem in which patients experience difficulty to evacuate stools and feel that the bowel is incompletely empty, which causes the need to put fingers in to the rectum or vaginal to…
- Trial name
- OPUS (NCT02239302)
- Where
- United Kingdom
- Volunteers
- 131 people
- Sponsor
- Croydon University Hospital
Dyssynergic Defecation, Puborectalis Syndrome
Puborectalis Syndrome as a Phenotype of Dyssynergic Defecation in Chronic Constipation: a Comparative Study of Defecography,High-resolution Anorectal Manometry, and Pelvic Floor Ultrasound
Patients with suspected DD who met the Rome IV criteria were divided into the DD group and other types of constipation groups. The differences between the two groups were analyzed to explore the precise diagnostic scheme for DD.
- Conditions
- Dyssynergic Defecation, Puborectalis Syndrome, Impaired Rectal Evacuation
- Trial name
- NCT07683390
- Testing
- Analysis of inter-group differences
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Third Military Medical University
Menopause, Perimenopausal Disorder
Pelvic Floor Symptoms Across Menopausel Stages
The menopausal transition is associated with substantial hormonal alterations that may adversely affect lower urinary tract function, bowel function, and sexual health.
- Trial name
- NCT07690137
- Testing
- Assessment for Lower Urinary Tract Symptoms, Assessment for Bowel Symptoms, Constipation Severity Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Bezmialem Vakif University
Ulcerative Colitis (Disorder), Familial Adenomatous Polyposis (FAP)
LATA-IBD TRIAL a Controlled Feasibility Study for the Introduction of Transanal Minimally Invasive IPAA-Surgery. Evaluation of Operative Results and Bowel Function After Introducing Transanal IPAA-surgery to Replace Conventional Laparoscopic IPAA-surgery.
This study compares the operative and functional outcomes of adding a transanal pathway to laparoscopic pelvic pouch surgery. The transanal pathway enables the surgeon to have better control when dividing the rectum and it may…
- Trial name
- LATA-IBD (NCT07278687)
- Where
- Sweden
- Volunteers
- 39 people
- Sponsor
- Sahlgrenska University Hospital
Postoperative Ileus
The Effect of Coffee After Resection of Small Bowel
Post-operative ileus ("post-op ileus") is a condition which can occur after surgery. This means that the bowels stop working correctly and food and liquids will not pass through in the normal manner.
- Trial name
- NCT03143621
- Testing
- Coffee, Water
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Mount Carmel Health System
Urinary Tract Infections, Recurrent Urinary Tract Infection
Chlorhexidine Lavage for Recurrent Urinary Tract Infection
A two-arm randomized control trial evaluating rates of urinary tract infection in post-menopausal women on vaginal estrogen with recurrent urinary tract infections.
- Trial name
- NCT06598514
- Testing
- Chlorhexidine, Sterile Water
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Oregon Health and Science University