Clinical trials: Bowel Incontinence
Gynecologic Cancers, Breast Cancer Female
Pelvic Health Rehabilitation After Breast and Gynecologic Cancer
The GYVE study aims at testing an online program (eModule) to help people who have had breast or gynecologic cancer and are experiencing pelvic health issues like urinary incontinence and pain during sex.
- Conditions
- Gynecologic Cancers, Breast Cancer Female, Incontinence, Incontinence Bowel
- Trial name
- GYVE (NCT06822582)
- Testing
- Pelvic Health Module
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Laval University
Total Colectomy, Diarrhea
Defining Ileorectal Syndrome: a Prospective Observational Study
1. Study Title: Trying to Define Ilorectal Syndrome: A Prospective Observational Study 2. Study Objective and Significance: Primary Objective: To prospectively evaluate the frequency, symptom severity, and impact on quality of…
- Conditions
- Total Colectomy, Diarrhea, Urgency Incontinence, Soilings, Fecal
- Trial name
- DEFINE-IRS (NCT07385196)
- Testing
- survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Urinary Incontinence, Fecal Incontinence
Perineal Massage and Pelvic Floor Exercise in the Antenatal Period
This study aimed to determine the effect of perineal massage and pelvic floor exercise in the antenatal period on sexuality and urinary and fecal incontinence in the postpartum period.
- Conditions
- Urinary Incontinence, Fecal Incontinence, Sexual Dysfunction, Sexuality
- Trial name
- NCT05624060
- Testing
- Pelvic Floor Dysfunction Prevention Training, Pelvic Floor Dysfunction Prevention Training and Perineal Massage, Pelvic Floor Dysfunction Prevention Training and Perineal Massage and Pelvic Floor Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bitlis Eren University
Faecal Incontinence
Pelvipower for Faecal Incontinence
Faecal incontinence (FI) is a common condition which drastically reduces patient's quality of life and for which there are few effective treatments.
- Trial name
- NCT05900726
- Testing
- High Resolution Anorectal Manometry, Endoanal Ultrasound, Bowel diary
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- The Functional Gut Clinic
Fecal Incontinence
Safety and Tolerability of a Single Intra-anal Dose of NRL001 in Healthy Volunteers
This study is conducted to explore the safety and tolerability and plasma pharmacokinetics of NRL001 after single intra-anal dose of 1mL cream at increasing concentrations.
- Trial name
- NCT01406925
- Testing
- NRL001 cream
- Where
- Bulgaria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norgine
Fecal Incontinence
Biofeedback for Fecal Incontinence
Fecal incontinence affects 2% of adults in the United States. Biofeedback has been recommended for the treatment of fecal incontinence because uncontrolled studies over the past 25 years suggest that these treatments are as…
- Trial name
- NCT00124904
- Testing
- Biofeedback, Kegel exercises
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Faecal Incontinence, Prostate Cancer
Faecal Incontinence in Prostate Cancer Survivors Treated Whith Radiotherapy
The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with…
- Trial name
- NCT04262609
- Testing
- hypofractionated radiotherapy
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Consorci Sanitari de Terrassa
Rectum Cancer, Quality of Life
Determining Early Development of Faecal Incontinence and Anorectal Muscle Function After Surgery for Rectal Cancer.
Background: Patients treated for rectal cancer are in high risk of developing poor quality of life and faecal incontinence. Faecal incontinence has a negative impact on quality of life.
- Conditions
- Rectum Cancer, Quality of Life, Faecal Incontinence, Low Anterior Resection Syndrome
- Trial name
- EDFI-Cohort (NCT03257332)
- Testing
- Low Anterior Resection for Rectum Cancer
- Where
- 2 sites in Denmark
- Sponsor
- Slagelse Hospital
Fecal Incontinence
Indirect Non-invasive Evaluation of Pudendal Neuropathy
Purpose: Pelvic floor is a complex anatomical entity and its neuromuscular assessment is evaluated through electromyography, evoked potentials and pudendal nerve terminal motor latency.
- Trial name
- NCT03933683
- Testing
- Pudendal nerve terminal motor latency assessment
- Where
- Italy
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Moisture Associated Skin Damage, Fecal Incontinence
Testing a Novel Barrier Cream for Fecal Incontinence in an Ambulatory Population
Liquid stool and diarrhea are associated with an increased risk for moisture-associated skin damage (MASD), and clinical evidence suggests that exposure to liquid stool is associated with severe MASD and extensive erosion of…
- Conditions
- Moisture Associated Skin Damage, Fecal Incontinence, Incontinence Associated Dermatitis
- Trial name
- NCT06370637
- Testing
- Barrier Cream, Dermategrity Everyday Barrier Cream
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Scotiaderm
Sacral Neuromodulation
Preliminary Outcomes of Sacral Neuromodulation Applications; Tertiary-Center Experience in Turkey
to report our patients' outcomes of SNM in tertiary health centres in Turkey
- Trial name
- NCT06098963
- Testing
- sacral neuromodulation
- Volunteers
- 16 people
- Sponsor
- Cigli Regional Training Hospital
Rectal Cancer
Italian Validation of the LARS Score
BACKGROUND and RATIONALE Colorectal cancer, with 49,000 new diagnoses expected in 2019 (27,000 in men and 22,000 in women) represents, in Italy, the third neoplasm in men (14%) and the second in women (12%).
- Trial name
- NCT04406311
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Constipation, Fecal Incontinence
Diagnosis of Functional Defecation Disorders in Childhood
Purpose To compare different kinds of diagnostic investigations in order to identify the most sensitive and least invasive when diagnosing constipation.
- Trial name
- NCT00230360
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fecal Incontinence
Combination Therapy With Biofeedback, Loperamide and Stool Bulking Agents
Background: Biofeedback and medical treatments have been extensively used for moderate fecal incontinence. There is limited data comparing and combining these two treatments.
- Trial name
- NCT02165475
- Testing
- Biofeedback, Loperamide, Stool bulking agent (stericulia or isphagula husk)
- Where
- Sweden
- Sponsor
- University Hospital, Linkoeping
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Obstetrical Perineal Injury and Anal Incontinence
Pelvic-perineal Disorders in Women With Sphincter Tears
According to INSEE, in 2016, in France, there were 785,000 births. According to the latest national perinatal survey in 2016, 80.4% of women gave birth by vaginal delivery.
- Trial name
- PAPOASI (NCT04862299)
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Faecal Incontinence
A Multi-centre, Phase II, Double-blind, Randomised, Placebo-controlled, Parallel Group, Dose-ranging Study in Patients With Faecal Incontinence; to Evaluate the Efficacy, Safety and Tolerability of Locally Applied NRL001 Over an 8 Week Treatment Period
The purpose of this study is to evaluate the safety, tolerability and efficacy of NRL001 in the treatment of faecal incontinence, compared against placebo
- Trial name
- NCT01656720
- Testing
- 1R, 2S-methoxamine hydrochloride
- Where
- 51 sites in Czechia, France and 7 more
- Volunteers
- 417 people
- Sponsor
- Norgine
High Transsphincteric Perianal Fistula
Intersphincteric Approach to Perianal Fistula With High Risk for Postoperative Fecal Incontinence
.Rerouting operation takes the advantage of minimal recurrence rate as well as minimal incontinence that is associated with less sphincter division,It is indicated in patients with transsphincteric fistula in whom lay open is…
- Trial name
- NCT02994524
- Testing
- Rerouting technique for transsphincteric perianal fistula
- Volunteers
- 25 people
- Sponsor
- Yasser Mohamed Abdel-samii
Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant
Efficacy and Safety of Transcutaneous Posterior Tibial Nerve Stimulation on Fecal Continence in Patients Undergoing Surgery for Rectal Neoplasia
Rectal neoplasia is one of the most prevalent cancers in Spain, and the treatment of choice is total mesorectal excision (TME), as it has demonstrated significant oncological improvements.
- Conditions
- Low Anterior Resection Syndrome (LARS), Rectal Neoplasm Malignant, Quality of Life (QOL), Fecal Incontinence (FI)
- Trial name
- NCT07632196
- Testing
- Posterior tibial nerve stimulation intervention group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa