Clinical trials: Bowel Obstruction
SBO - Small Bowel Obstruction
A Multicenter Retrospective Review of Management Strategies in Small Bowel Obstruction
The objective of the study is to review performance of water soluble contrast study in patients admitted with Small Bowel Obstruction(SBO), will improve quality and safety, and decrease length of stay and morbidity.
- Trial name
- NCT06223620
- Testing
- review performance of water soluble contrast
- Where
- United States
- Volunteers
- 504 people
- Sponsor
- Methodist Health System
Neuroendocrine (NE) Tumors, Metastasis
Resection of the Primary Tumor vs. Systemic Treatment Alone for Patients With Small Intestinal Neuroendocrine Tumors and Unresectable Metastases: a Europe-wide Study
When possible, surgery to completely remove small intestinal neuroendocrine tumors (siNETs) is always recommended. However, in cases where the tumor has spread and cannot be cured completely, it is unclear whether a surgical…
- Conditions
- Neuroendocrine (NE) Tumors, Metastasis, Bowel Obstruction
- Trial name
- ENETSSurgSmInt (NCT06787014)
- Testing
- Histopathological review
- Where
- Switzerland
- Volunteers
- 3,200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Large Bowel Obstruction
International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes
Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare…
- Trial name
- IMPEL (NCT07458867)
- Volunteers
- 500 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Adhesive Small Bowel Obstruction
Predictors of Laparoscopy Conversion in Adhesive Small Bowel Obstruction
The goal of this observational study is to reveal predictors of unsuccessfull laparoscopic intervention in adult patients with adhesive small bowel obstruction.
- Trial name
- NCT07350447
- Testing
- Laparoscopic adhesiolysis, Laparotomic adhesiolysis
- Where
- 7 sites in Russia
- Volunteers
- 170 people
- Sponsor
- Almazov National Medical Research Centre
Acute Abdomen, Bowel Obstruction
The Best Care for Abdominal Emergencies Study
This is a single-centre retrospective cohort study utilising electronic hospital records. The aim of this study is to improve care for all patients with an intestinal emergency, irrespective of whether they have surgery or not.
- Conditions
- Acute Abdomen, Bowel Obstruction, Bowel; Ischemic, Acute, Bowel Perforated
- Trial name
- BCAE (NCT04577339)
- Testing
- Laparotomy or laparoscopy
- Where
- United Kingdom
- Volunteers
- 2,500 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi
Small Bowel Obstruction, Small Bowel Obstruction Adhesion
Aetiologies and Prognosis of Small Bowel Obstruction in Virgin Abdomen
Small bowel obstruction (SBO) is a surgical emergency in which the passage of intestinal contents is prevented due to mechanical obstruction of small intestine.
- Trial name
- NCT07150390
- Where
- China
- Volunteers
- 312 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Small Bowel Obstruction
Water-Soluble Contrast Induced Intestinal Stimulation for the Treatment of Small Bowel Obstruction: A Feasibility Study
Small bowel obstruction (SBO) is common yet, how to best manage it remains unknown. One approach is to administer water soluble oral contrast (WSC) and the obtain x-rays to determine how well the bowel is functioning.
- Trial name
- NCT07099300
- Testing
- Abdominal Radiography
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions
Adhesion Prevention in ASBO Surgery Using 4DryField® PH
Post-surgical adhesions occur in up to 90% of abdominal surgeries, often leading to complications like adhesive small bowel obstruction (ASBO) and chronic pain.
- Conditions
- Adhesive Small Bowel Obstruction, Postoperative Abdominal Adhesions, Bowel Obstruction, Abdominal Surgery Complications
- Trial name
- ADHERE (NCT07078981)
- Volunteers
- 189 people
- Sponsor
- Alessio Giordano
Resolution of Bowel Obstruction
The Application of Ultrasound in the Evaluation of Patients With Colon Cancer-related Obstruction Receiving Colonic Stent Placement
Bowel ultrasound may serve as a diagnostic tool to detect the resolution of bowel obstruction. In this study, we aim to validate the use of bowel ultrasound to evaluate patients with colon obstruction receiving colonic stents at…
- Trial name
- NCT06997848
- Testing
- colonic stent
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Small Bowel Obstruction
A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction
Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically.
- Trial name
- ALPROC (NCT03905239)
- Testing
- algorithm
- Where
- France
- Volunteers
- 488 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Short Bowel Syndrome, Intestinal Fistula
Intralipid Versus SMOFlipid in HPN Patients
This study will randomize all patients who are new to the Mayo Clinic HPN team to either standard lipid emulsion (Intralipid) or SMOFLipid.
- Conditions
- Short Bowel Syndrome, Intestinal Fistula, Crohn Disease, Intestinal Obstruction
- Trial name
- NCT03773237
- Testing
- SMOFLipid, Intralipid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mayo Clinic
Small Bowel Obstruction, Intestinal Pseudo-Obstruction
Predicting NOM Failure in Bowel Obstruction
"This study aims to collect data on patients with small bowel obstruction (SBO) admitted to hospitals in France and Italy from May 2022 to October 2024 to develop a deep convolutional neural network (DCNN) model.
- Trial name
- NCT06711107
- Where
- France
- Volunteers
- 370 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Small Bowel Obstruction Adhesion
Small Bowel Obstruction in Virgin Abdomen
A retrospective study conductet at Estonia's two regional hospitals. The data of patients hospitalised for SBO (small bowel obstruction) between 2015-2019 is retrospectively analysed.
- Trial name
- NCT06912581
- Where
- Estonia
- Volunteers
- 223 people
- Sponsor
- University of Tartu
Small Bowel Obstruction
Study About Contrast Media
Patients hospitalized with adhesive small bowel obstruction (SBO) are randomized to 2 study groups at admission after signing an informed consent form.
- Trial name
- NCT05678023
- Testing
- Effect on contrast media depending on the time of its administratsion
- Where
- Estonia
- Volunteers
- 120 people
- Sponsor
- University of Tartu
Adhesive Small Bowel Obstruction
Comparison of Outcomes of Management of Bowel Obstruction Pilot Study
The Comparison of Outcomes of Management of Bowel Obstruction (COMBO Pilot) Pilot trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with…
- Trial name
- COMBO Pilot (NCT06817551)
- Testing
- Dexamethasone, Supportive Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Small Bowel Obstruction
REsectability Small Bowel Obstruction LAParoscopic (RESBOLAP) Score. Multicentric Data Registry
AIM OF THE STUDY The aim of the study is to develop a Resectability Laparoscopic Score as a helpful instrument during intraoperative decision-making in the setting of emergency laparoscopic surgery for small bowel obstruction…
- Trial name
- RESBOLAP (NCT05842135)
- Testing
- Laparoscopic approach to small bowel obstrcuction
- Where
- Italy
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- San Salvatore Hospital, AST Pesaro-Urbino
Adhesive Small Bowel Obstruction
Elective Adhesiolysis vs. a Wait-and-see Policy to Prevent Recurrences After Conservative Treatment of Adhesive Small Bowel Obstruction
Rationale: Adhesive small bowel obstruction (aSBO) is a frequent surgical emergency, associated with 3-8% hospital mortality and a high risk of recurrence (20% at two years of follow-up).
- Trial name
- AWARE (NCT06777446)
- Testing
- Elective Adhesionlysis, Adhesion barrier
- Where
- 14 sites in Belgium, Netherlands
- Volunteers
- 380 people
- Sponsor
- Radboud University Medical Center
Small Bowel Obstruction
SnapSBO - Small Bowel Obstruction Snapshot Audit
Small bowel obstruction (SBO) and its complications are frequently seen in patients admitted through the Emergency Departments of all acute care hospitals2.
- Trial name
- SnapSBO (NCT05843097)
- Where
- Spain
- Volunteers
- 1,900 people
- Sponsor
- European Society for Trauma and Emergency Surgery