Clinical trials: Bra
Child Development
A Home Visiting Program for Pregnant Youth to Promote Early Brain Development II
Home visiting programs for pregnant women aiming to improve mother-infant relationship has received worldwide attention in the past 30 years.
- Trial name
- NCT04362098
- Testing
- Home visiting Program for Young Pregnant Women
- Where
- Brazil
- Volunteers
- 167 people
- Sponsor
- University of Sao Paulo
Methicillin Resistant Staphylococcus Aureus
Study of Methicillin-resistant Staphylococcus Aureus (MRSA) Isolated From Infected Patients in Brazil
This project has as general objective to determine if there is any Methicillin-resistant Staphylococcus aureus (MRSA) strain disseminating in the hospital of Belo Horizonte.
- Trial name
- MRSABrazil (NCT01359358)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Chikungunya Virus Infection
Observational Study to Assess the Effectiveness of VLA1553 Vaccine in Preventing Chikungunya During a Pilot Vaccination Strategy in Brazil
This is an observational, non-interventional, test-negative case-control (TNCC) study to estimate the vaccine effectiveness of VLA1553 against Chikungunya virus in a real-world setting.
- Trial name
- NCT07347002
- Testing
- Live-attenuated CHIKV vaccine VLA1553
- Where
- 3 sites in Brazil
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
Malaria, Vivax, G6PD Deficiency
Operational Feasibility of Appropriate Radical Cure of Plasmodium Vivax With Tafenoquine or Primaquine After Quantitative G6PD Testing in Brazil
This is an observational study carried out in Brazil in patients with P. vivax malaria. The study will be carried out in the municipalities of Manaus (state of Amazonas) and Porto Velho (state of Rondônia).
- Trial name
- Trust (NCT05096702)
- Testing
- Tafenoquine, Primaquine
- Where
- 41 sites in Brazil
- Volunteers
- 16,000 people
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
Coronary Artery Disease
FIM-BR - First-in-Man Study (Brazil Part) With Sirolimus-Coated BX VELOCITY Stent
This is a single center, non-randomized study. Patients will be treated with the sirolimus coated Bx VELOCITY Balloon-Expandable Stent mounted on the Raptor OTW SDS.
- Trial name
- NCT00233792
- Testing
- sirolimus coated Bx VELOCITY stent - fast release, sirolimus coated Bx VELOCITY stent - slow release
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Cordis US Corp.
Carcinoma, Non-Small-Cell Lung
Durvalumab as Maintenance in Patients Who Received Chemoradiotherapy for Unresectable Stage III NSCLC: Real World Data From an Expanded Access Program in Brazil
Durvalumab as maintenance in patients who received chemoradiotherapy for unresectable stage III NSCLC: Real World Data from an Expanded Access Program in Brazil
- Trial name
- NCT04948411
- Where
- 4 sites in Brazil
- Volunteers
- 33 people
- Sponsor
- Latin American Cooperative Oncology Group
Glaucoma
Assessing the Efficacy and Tolerability of AZARGA® (Brinzolamide 1%/Timolol 0.5% Fixed Combination) as Replacement Therapy in Patients on COMBIGAN® (Brimonidine 0.2%/Timolol 0.5% Fixed Combination) Therapy in Brazil
The purpose of this study was to assess the efficacy and tolerability of changing to AZARGA® from prior COMBIGAN® pharmacotherapy in patients with open-angle glaucoma or ocular hypertension.
- Trial name
- NCT01514734
- Testing
- Brinzolamide/timolol maleate fixed combination
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Alcon Research
Brassiere Strap Fat (BSF), Bra Strap Fat (BSF)
Efficacy and Safety of Deoxycholic Acid Injections for Removal of Adipose Tissue in the "Bra Strap Fat" Region
This study evaluates the safety and efficacy of deoxycholic acid injections to dissolve adipose tissue in the anterior and posterior aspect of the axilla or the so called "brassiere strap fat" (BSF).
- Trial name
- NCT04089722
- Testing
- Deoxycholic Acid
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Juva Skin & Laser Center
Univentricular Heart, Lymphatic Abnormalities
Lymphatic Function in Patients With a Fontan Circulation From Brazil
It is suggested that the elevated central venous pressure in patients with a Fontan circulation can provoke manifestation of lymphatic dysfunction, met as plastic bronchitis, peripheral oedema and most feared protein-losing…
- Conditions
- Univentricular Heart, Lymphatic Abnormalities, Lymphatic Edema
- Trial name
- NCT04394507
- Testing
- Near-Infrared Fluorescence imaging, Strain Gauge Plethysmography
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mental Health Wellness 1, COVID
Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Services in the Context of COVID-19
A pragmatic superiority randomized controlled trial comparing Telepsychoeducation plus personalized videos vs. Telepsychoeducation without personalized videos for the prevention of future emotional distress in professionals and…
- Conditions
- Mental Health Wellness 1, COVID, Emotional Distress, Depressive Symptoms
- Trial name
- NCT04632082
- Testing
- Telepsychoeducation with personalized videos, Telepsychoeducation without personalized videos
- Where
- Brazil
- Volunteers
- 2,200 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
COVID-19, Lymphocytopenia
InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection (Brazil Cohort)
Comparison of the effects of CYT107 vs Placebo administered by intra-muscular route (IM) at 10μg/kg twice a week for three weeks on immune reconstitution of lymphopenic COVID-19 patients
- Trial name
- ILIAD-7-BRA (NCT04927169)
- Testing
- Interleukin-7
- Where
- 6 sites in Brazil
- Volunteers
- 4 people
- Sponsor
- Revimmune
Stool Assessment, Skin Rash
GI Symptoms in Infants Fed Goat Milk-based Infant Formula
A cross-sectional observational survey was conducted in Brazil, Mexico, Russia, and The Netherlands by recruiting parents/legal guardians through social media.
- Conditions
- Stool Assessment, Skin Rash, Urticaria, Regurgitation
- Trial name
- NCT06755424
- Where
- Netherlands
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Menopause, Metabolic Syndrome
Low Sexual Desire and Metabolic Syndrome
Objective: To evaluate the prevalence of hypoactive sexual desire disorder (HSDD) in postmenopausal women diagnosed with metabolic syndrome (MS) and to compare it to that of a control group without MS.
- Conditions
- Menopause, Metabolic Syndrome, Hypoactive Sexual Desire Disorder, Obesity
- Trial name
- NCT02430987
- Testing
- Female sexual function index questionnaire, Evaluation of presence of metabolic syndrome, Evaluation of the body mass index
- Where
- Brazil
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Nutritional and Metabolic Diseases
The Nutritional Status and Food Intake of Community Health Agents
This research had as a goal to characterize the social demographic profile, nutritional status, the presence of chronic non-transmissible diseases and food intake of the community health agents who belong to five family health…
- Trial name
- NCT00682604
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Unidade Itaquera
Postoperative Pain, Postoperative Complications
Protocol for Accelerated Recovery in Patients Undergoing Thoracic Surgical Procedures (PROSM). Study Randomized Comparative Between the Adoption of the Proposed Guidelines and the Traditional Method Currently Used in the Institution
Introduction: Aiming at reducing costs and optimizing the use of these financial resources, several postoperative recovery protocols have emerged that aim to reduce the length of hospital stay by accelerating surgical…
- Conditions
- Postoperative Pain, Postoperative Complications, Postoperative Nausea, Lung Cancer
- Trial name
- PROSM (NCT03271749)
- Testing
- PROSM guidelines for preoperative, anesthesia and postoperative care for lung resections
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Igor Renato Louro Bruno de Abreu
Dengue
Assessing the Effectiveness of Sanofi Pasteur's Dengue Vaccine (Dengvaxia) Against Hospitalization and Symptomatic Infection in the State of Parana - Brazil
The study seeks to assess the effectiveness of Sanofi Pasteur´s dengue vaccine (Dengvaxia®) according to the age, dose and municipality of residence in five municipalities of Paraná State.
- Trial name
- NCT03960385
- Testing
- CYD-TDV
- Where
- Brazil
- Volunteers
- 1,854 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Child Development
A Home Visiting Program for Pregnant Youth to Promote Early Brain Development
Home visiting programs for pregnant women aiming to improve mother-infant relationship has received worldwide attention in the past 30 years.
- Trial name
- NCT02807818
- Testing
- Home visiting Program for Young Pregnant Women
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo
Breast Ptosis
Hybrid Autologous Breast Augmentation in Mastopexy With Internal BRA Fixation; Using Local Breast Tissues and Fat Grafting
The breast is a very important organ for women's self-esteem and is regarded as a symbol of femininity. Deviations from normal size, shape, and symmetry are interpreted as unattractive and a sign of aging.
- Trial name
- NCT07197190
- Testing
- Autologous augmentation mastopexy with subpectoral lipofilling and upper and medial pole fat grafting.
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Assiut University
Severe Asthma
BRazilian Asthmatics Patients EOSinophilic Profile (BRAEOS)
Asthma is a complex and heterogeneous disease. Severe asthma is recognised as a major unmet need that poses a great burden on the healthcare system.
- Trial name
- BRAEOS (NCT03925415)
- Where
- 6 sites in Brazil
- Volunteers
- 414 people
- Sponsor
- AstraZeneca
Lung Neoplasms
Intensified Chemo-immuno-radiotherapy With Durvalumab for Stage III Non-Small Cell Lung Cancers
This is a phase II study that will assess if Durvalumab (MEDI4736) used as induction chemo-immunotherapy followed by concurrent chemo-immuno-radiotherapy and consolidation immunotherapy may improve oncologic outcomes compared…
- Trial name
- PACIFIC BRAZIL (NCT04230408)
- Testing
- Durvalumab
- Where
- 6 sites in Brazil
- Volunteers
- 48 people
- Sponsor
- Latin American Cooperative Oncology Group