Clinical trials: Braces
Multiple Sclerosis
VR and Orthoses for Rehabilitation in Multiple Sclerosis
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis…
- Trial name
- VIRTUE (NCT07096700)
- Testing
- VR and walking brace-based gait rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 12 people
- Sponsor
- Azienda Usl di Bologna
Sever's Disease
Comparison of Braces for Treatment of Sever's Disease
This study is to learn more about braces that may help young athletes diagnosed with Sever's disease. Young athletes with this diagnosis who are seen by a Sports Medicine doctor will be asked it they want to be a part of the…
- Trial name
- NCT03494647
- Testing
- Cheetah Heel Cup, The X Brace
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Ankle Fracture, Recovery
Physical Recovery During Bracing After Ankle Fracture (Re-BAF)
Ankle fractures are among the most common fractures and represent the second most frequent fracture type requiring surgery. Many patients experience long-term pain, stiffness, and reduced ankle function, which substantially…
- Conditions
- Ankle Fracture, Recovery, Physical Activity, Rehabilitation
- Trial name
- Re-BAF (NCT07521696)
- Testing
- Ankle stirrup, Foot-ankle brace
- Where
- Denmark
- Volunteers
- 280 people
- Sponsor
- Odense University Hospital
Dental Caries, Streptococcus Mutans
Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics
Background This study is part of a doctoral research project at Universidad Cardenal Herrera CEU (Spain), directed by Prof. Santiago Arias de Luxán and conducted by doctoral candidate Shirli Kelmendi within the PhD program in…
- Conditions
- Dental Caries, Streptococcus Mutans, Tooth Demineralization, Orthodontic Appliances, Fixed
- Trial name
- MIPASTEORTHO (NCT07244991)
- Testing
- MI Paste Plus (CPP-ACP with Sodium Fluoride)
- Where
- 2 sites in Albania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Class II Malocclusion
the Condylar Response of Mini-plate Anchored Rigid Fixed Functional Appliance Versus Dentally Anchored Semi-rigid One
This study will be directed to evaluate The effect of two different types of fixed functional appliances on the temporomandibular joint. Study design: Prospective randomized clinical study.
- Trial name
- NCT05466344
- Testing
- Herbst Group, TFBC Group
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Malocclusion, Angle's Class
Precision Orthodontics: Virtual Treatment Planning for Orthodontic Braces
The investigators are evaluating the effectiveness of custom-made 3D-printed ceramic (tooth-colored) brackets (braces) compared to conventional tooth-colored brackets (braces).
- Trial name
- NCT04002999
- Testing
- 3D printed ceramic bracket and tray, Stock ceramic bracket + 3D printed tray, Stock bracket, no tray
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Angle Class 2 Malocclusion
Clear Aligners vs Fixed Appliances for Molar Distalization Using Infrazygomatic Crest Screws
This study compares three different methods of moving upper back teeth backward (distalization) to create space for crowded or protruding teeth, all supported by small temporary screws placed in the cheekbone area (infrazygomatic…
- Trial name
- NCT07714603
- Testing
- Pitts21® fixed appliance, Invisalign® Clear Aligners, ClearCorrect Clear Aligners
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- TC Erciyes University
Class II Division 1 Malocclusion
Comparison of Treatment Effects of PowerScope2 and Forsus Using CBCT
The main objective of this prospective, controlled clinical study is: 1. To compare the treatment effects of PowerScope2 and Forsus Fatigue Resistant Device in patients with Class II divison1 malocclusion. 2.
- Trial name
- NCT03296644
- Testing
- Class II correction using PowerScope2, Class II correction using Forsus
- Where
- India
- Volunteers
- 42 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Orthodontic Appliance Complication
Control of Pain From Braces With Patient Advice Sheets
To compare the analgesic property of acupressure with NSAIDs (Ibuprofen) in controlling pain following orthodontic treatment. This will be achieved by assessing the effectiveness of acupressure in controlling pain and discomfort…
- Trial name
- COPPAS (NCT03159520)
- Testing
- Advice sheet
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- University of Dundee
Motivational Interviewing, Oral Hygiene
Motivational Interview and Orthodontic Patients
A parallel-group randomized clinical trial was conducted with 45 patients of the Orthodontic Clinic of Universidad Iberoamericana's (UNIBE) Postgraduate Unit.
- Conditions
- Motivational Interviewing, Oral Hygiene, Orthodontic Appliance Complication
- Trial name
- NCT04871373
- Testing
- Motivational interviewing, Oral Hygiene Instructions
- Where
- Dominican Republic
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Iberoamericana
S.Mutans Colonization in Adults With Fixed Orthodontic Appliance
Changes in Streptococcus Mutans Colonization With Different Oral Hygiene Protocols in Adult Patients With Fixed Orthodontic Appliance
Fixed orthodontic appliances increase the rate of plaque accumulation around orthodontic brackets and gingival margins. It was also found that the amount of plaque accumulation and S.mutans level around banded orthodontic…
- Trial name
- NCT05016713
- Testing
- Chlorhexidine mouthwash, Interdental brush, Fluoride-based toothpaste
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth
Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction Cases
Patients who have severe crowding that require four premolars extraction will be treated in this study. The efficacy of the clear aligners and vestibular fixed appliances will be assessed.
- Conditions
- Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth, Crowding
- Trial name
- NCT03645356
- Testing
- Fixed Appliances, Clear Aligners
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Orthodontic, Pain
Impact of Photobiomodulation on Pain Associated With Orthodontic Treatment
Orthodontic treatment can cause pain. Research studies have shown that light therapy can help reduce pain that is caused by orthodontic treatment.
- Trial name
- NCT06289595
- Testing
- PBM Ortho device
- Where
- 7 sites in Japan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PBM Healing International Limited
Orthodontic Pain (D013850), Pain Management (D016146)
A Randomized Clinical Trial of the Effectiveness of Acupressure in Relieving Orthodontic Pain
Orthodontic treatment with fixed appliances often causes pain, which peaks within 24 hours after archwire placement and lasts for several days.
- Conditions
- Orthodontic Pain (D013850), Pain Management (D016146), Acupressure (D056351), Analgesics, Non-Narcotic (D000700)
- Trial name
- NCT06812936
- Testing
- Acetaminophen, Acupressure
- Where
- Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Fixed Orthodontic Retainer
Ultrasonographic Evaluation of Periodontal Effects of Fixed Retainers
This prospective clinical study aims to evaluate the effects of fixed lingual retainers placed after orthodontic treatment on periodontal soft and hard tissue parameters using ultrasonographic imaging.
- Trial name
- NCT07414264
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Selcuk University
Dental Caries
Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients
AIM: To evaluate the efficacy of daily tooth brushing with high concentrated fluoride dentifrice on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA).
- Trial name
- NCT01768390
- Testing
- toothpaste containing 5,000 ppm fluoride, 1450 GCP
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Orthodontic Appliance Complication
Using Probiotics to Improve Oral Hygiene During Orthodontic Treatment
Fifty patients needing non-extraction-based metallic orthodontic treatment will be divided randomly into the probiotic group and the control group.
- Trial name
- NCT06641960
- Testing
- Probiotics, Traditional treatment
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Anterior Cruciate Ligament Injuries, Arthroscopy
Functional Outcomes Comparison in Patients Using Knee Brace Post ACL Reconstruction With Autograft Bone Quadricep Tendon
This study is a study looking for the relationship between variables with a prospective cohort design to determine functional outcomes subjectively and objectively in patients with and without braces after ACL reconstruction with…
- Conditions
- Anterior Cruciate Ligament Injuries, Arthroscopy, Braces
- Trial name
- ACL (NCT05457452)
- Testing
- Knee Brace
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Orthodontic Appliance Complication, Tooth Demineralization
Fluoride Delivery to Prevent White Spots During Orthodontic Treatment
The aim of this 2-armed, parallel, randomised, controlled trial is to assess the effect of different ways of applying fluoride to teeth on the formation of white spots (enamel demineralisation), during orthodontic treatment with…
- Trial name
- FL4OWS (NCT05005689)
- Testing
- Fluoride mouthwash (0.05%; 225ppm)., Tooth Mousse Plus
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
White Spot Lesion
The Effect of ICON Treatment on WPL With Patients After Fixed Orthodontic Appliances
The aim of this study is to determine the effect of ICON on White spot lesions compared to CPP-ACPF plus.
- Trial name
- NCT03391180
- Testing
- ICON Remineralization, CPP-ACPF
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy