Clinical trials: Brain Activity
Foot, Footwear
Footwear and Brain Activity in Children
Childhood is a critical period for neuromotor development, during which footwear may influence both gait biomechanics and the integration of sensory and motor control processes.
- Conditions
- Foot, Footwear, Children
- Trial name
- FooTBAC (NCT07151352)
- Testing
- Starting Condition - Barefoot, Barefoot-Style Footwear, Conventional Footwear with Heel Drop
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Stroke
Using Wireless-technology for Feedback of Daily Walking Activity Post-stroke
Regaining independent walking is the top priority for individuals recovering from stroke. Thus, physical rehabilitation post-stroke should focus on improving walking function and endurance.
- Trial name
- NCT01521234
- Testing
- Feedback of daily walking activity
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Toronto Rehabilitation Institute
Parkinson's Disease
Efficacy of Levodopa/Carbidopa/Entacapone vs Levodopa/Carbidopa in Parkinson's Disease Patients With Early Wearing-off
The study evaluated the efficacy of levodopa/carbidopa/entacapone vs levodopa/carbidopa in patients with Parkinson's disease and early wearing-off with levodopa
- Trial name
- NCT00391898
- Testing
- Levodopa/carbidopa/entacapone, Levodopa/carbidopa
- Where
- 26 sites in Spain
- Volunteers
- 95 people
- Sponsor
- Novartis
Alzheimer Disease, Agitation
Nabilone for Agitation Blinded Intervention Trial
This study will look at whether nabilone is an effective treatment for agitation in Alzheimer's disease (AD) patients. Agitation is highly prevalent in patients with AD and is one of the most distressing and challenging-to-treat…
- Trial name
- NAB-IT (NCT04516057)
- Testing
- Nabilone
- Where
- 6 sites in Canada
- Volunteers
- 112 people
- Sponsor
- Sunnybrook Health Sciences Centre
Epilepsy
Electrohaemodynamic Activity in Epileptic Children : Combined Video-EEG and Near-infrared Spectroscopy (NIRS) Analysis
Evaluate the contribution of multimodal high-resolution EEG-NIRS electrical and local haemodynamic analysis to spatial localization of epileptogenic foci
- Trial name
- NIRS Epilepsie (NCT02814331)
- Testing
- multimodal high-resolution EEG-NIRS
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Parkinson's Disease, Physical Activity
Effect of High Intensity Interval Training on Mechanisms of Neuroplasticity in Parkinson's Disease Patients
There are experimental evidences of the important role of high intensity physical exercise in Parkinson's disease (PD) treatment, that induces similar effects to pharmacotherapy.
- Conditions
- Parkinson's Disease, Physical Activity, Neurorehabilitation, Neuroplasticity
- Trial name
- NCT04204551
- Testing
- high-intensity interval training (HIIT), conventional physical therapy
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Stroke, Hemiplegia
E-Rehabilitation: Aerobic Resistance Training for Stroke Survivors
This pilot study intends to evaluate an online exercise video rehabilitation program for stroke survivors with moderate disability compared to usual care.
- Trial name
- NCT02938000
- Testing
- Theraband with exercise video, usual care with advice to exercise
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Kaiser Permanente
Stroke
The Active Transition Home Post-Stroke Program
Post-stroke participants will wear wearable sensors for one week at 1-week prior to discharge from inpatient rehabilitation, 3- and 7- weeks post-discharge and 3-months post-discharge.
- Trial name
- NCT06119230
- Testing
- Activity Counselling
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Schizophrenia
Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
This study will investigate the effects of intermittent Theta Burst Stimulation (iTBS) on natural oscillatory frequency of the dorsolateral prefrontal cortex (DLPFC) and working memory in early-course schizophrenia (EC-SCZ).
- Trial name
- REDOCS (NCT05102929)
- Testing
- active intermittent Theta Burst Stimulation (iTBS)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Fabio Ferrarelli
Insulin Sensitivity
The Importance of Insulin Action in the Brain for the Immune System During Physical Activity
The goal of this clinical trial is to clarify the interaction of central insulin action and physical activity with the immune system. Therefore, participants will undergo bicycle spiroergometer tests.
- Trial name
- NCT06552130
- Testing
- Spiroergometer test with intranasal insulin spray
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Stroke
Muscle Activity of the Upper Limb Between Task-Specific and Robot Assisted Training Among Individuals Post Stroke
The investigators compared the activity and fatigue of upper extremity muscles, pain levels, subject satisfaction levels, perceived exertion, and number of repetitions in Task-Specific Training (TST) compared with Robot-Assisted…
- Trial name
- NCT03575481
- Testing
- The RAT and The TST
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Alzheimer's Disease
Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients
This study will assess the safety, tolerability and Abeta-specific antibody response of repeated intra-muscular injections of adjuvanted CAD106 in patients with mild Alzheimer's Disease.
- Trial name
- NCT01097096
- Testing
- CAD106, Alum, MF59
- Where
- 31 sites in United States, Belgium and 8 more
- Volunteers
- 177 people
- Sponsor
- Novartis Pharmaceuticals
Nicotine Dependence
Effects of Varenicline on Brain Activity During Nicotine Abstinence
This project aims to define mechanisms through which varenicline might be an effective smoking cessation medication.
- Trial name
- NCT00602927
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Mild Cognitive Impairment, Cerebral Blood Flow
A Study of Low-level Light Therapy Using Photo-activated Modulation Ameliorates Cognitive Deficits
The primary objective of this study is to confirm and compare the effect of methods of Low-level light therapy (LED-T) in the mild cognitive impairment.
- Conditions
- Mild Cognitive Impairment, Cerebral Blood Flow, Low-level Light Therapy, Brain Activity
- Trial name
- NCT03192670
- Testing
- Low-level light therapy device
- Where
- 2 sites in South Korea
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Yong-il Shin, MD
Neck Pain
Effects of Manual Therapy Combined With Therapeutic Exercise on Brain Biomarkers in Neck Pain
Structural brain alterations in pain-related areas have been demonstrated in patients with nonspecific neck pain. While manual therapy combined with therapeutic exercise is an effective management for neck pain, its underlying…
- Trial name
- NCT05568394
- Testing
- Manual therapy combinded with therapeutic exercise, Routine physical therapy
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Chiang Mai University
Alzheimer Disease
Multimodal Imaging Study on Physical Activity in Patients With Alzheimer's Disease
This study aims to gain a better understanding of metabolic early changes in neurodegenerative diseases, in order to enable new diagnostic and therapeutic approaches in the future.
- Trial name
- DEMENTIA-MOVE (NCT03939286)
- Testing
- Clinical-neurological and neuropsychological tests, Blood sampling, Assessment of physical activity via fitness tracker/diary
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- RWTH Aachen University
Parkinson Disease
A Study to Evaluate Safinamide's Effect on Dopamine and Serotonin's Availability by Using Brain Imaging
This is a study of safinamide, an investigational drug for Parkinson disease (PD). Safinamide is being developed as add-on therapy for the treatment of Parkinson disease.
- Trial name
- NCT01264861
- Testing
- Safinamide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Newron Pharmaceuticals SPA
Brain Tumour, Metastatic Cancer
Rurality Adapted Physical Activity Sport Health
Physical activity (PA) has been an integral part of non-drug therapy since the early 2010s. This supportive care is likely to reduce fatigue and improve the quality of life of patients during and after the cancer treatment phase.
- Trial name
- RAPASS (NCT05981170)
- Testing
- Adapted physical activity at home
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Institut Cancerologie de l'Ouest
Cerebral Palsy, Diplegia
Dual-task Training in Children With Cerebral Palsy
There are studies investigating the dual-task effect in sitting, standing up without sitting and walking in children with spastic CP.
- Conditions
- Cerebral Palsy, Diplegia, Hemiplegic Cerebral Palsy, Physical Disability
- Trial name
- NCT04777773
- Testing
- dual-task training
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Sema BÜĞÜŞAN ORUÇ
Executive Function, Neurosciences
Different Domains of Executive Function Dual Task Walking on Brain Activation and Gait Performance in Healthy Adults
The aim of this study is to investigate the effects of different domains of executive function (EF) during dual task walking condition on brain activation and gait performance in healthy adults.
- Trial name
- NCT04905186
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital