Clinical trials: Brain Activity
Glioma Glioblastoma Multiforme, High Grade Glioma (III or IV)
Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas
Gliomas are the most common malignant brain tumors, which are often associated with high-grade tumors characterized by an inferior prognosis and low patient survival rates in both children and adults.
- Trial name
- NCT06687681
- Testing
- NK cell therapy
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Marzieh Ebrahimi
Hepatic Encephalopathy
Effect of Rifaximine on Sleep Disorders in Patients Suffering From Hepatic Encephalopathy
Hepatic encephalopathy is responsible for sleep disturbances and daytime sleepiness. The purpose of our study is to assess sleep quality, quantity, sleep schemes and physical activity in patients suffering from HE, before and…
- Trial name
- NCT02163837
- Testing
- rifaximine
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Huntington's Disease
The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease
To examine the benefits of using a video-game, Dance, Dance, Revolution, as an exercise modality to improve gait and balance in individuals with Huntington's disease.
- Trial name
- NCT01735981
- Testing
- Video game exercise using Dance Dance Revolution, hand-held video game
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Anne Kloos
Pediatric Cancer, Pediatric Brain Tumor
Playful Sensorimotor Training in Pediatric Brain Tumor Patients
Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and clinically relevant side-effect of cancer treatment.
- Conditions
- Pediatric Cancer, Pediatric Brain Tumor, Chemotherapy-induced Peripheral Neuropathy, Sensorimotor Polyneuropathy
- Trial name
- RESET (NCT03334162)
- Testing
- Sensorimotor training
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Basel
Exploratory Behavior
The Role of Endogenous GLP-1 (Glycolipoprotein) in Regulating Glucose Stimulated Brain Activity
Our objective is to investigate neuro-anatomical correlates of the regulation of energy intake by means of functional MRI. Administration of glucose with and without lactisole and exendin as well as fructose is followed by…
- Trial name
- NCT01918566
- Testing
- tap water, Single intragastric instillation of 75g Glucose in 300ml tap water via nasogastric tube, Single intragastric instillation of 75g Glucose in 300ml tap water with 450ppm lactisole
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Elderly People
Improving the Quality of Life of Elderly Individuals Living in Nursing Homes
The development of physical activity (PA) and exercise habits improves strength, flexibility, balance and coordination, activities such as walking, sleep quality and cognitive status in elderly people and supports their…
- Trial name
- NCT06520956
- Testing
- Video based exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Metastatic Brain Tumor, Cerebral Metastases
Impact of Cognitive Rehab and Physical Activity on Cognition in Patients With Metastatic Brain Tumors Undergoing RT
To determine the feasibility of processes and instruments with an overarching purpose to guide the design of a larger study. To determine the feasibility of individuals with metastatic brain tumor(s) to engage in physical…
- Trial name
- NCT03096431
- Testing
- Physical Activity, Cognitive rehabilitation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University
Acute Ischemic Stroke
Study of Compound Edaravone Injection for Treatment of Acute Ischemic Stroke
The primary objective of the study is to confirm the efficacy of compound Edaravone Injection via intravenous infusion every 12 hours in the patients with Acute Ischemic Stroke(AIS) in a double-blind, active-controlled manner.
- Trial name
- NCT04984577
- Testing
- Compound Edaravone Injection-Low dose, Compound Edaravone Injection-High dose, Edaravone Injection
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Nanjing Yoko Biomedical Co., Ltd.
Stroke, Depression
Task-Oriented Rehab With SaeboFlex: Impact on Independence, Visual Motor Skills, and Depression in Stroke Patients
Objective: The SaeboFlex orthosis is designed to assist individuals with upper extremity weakness in performing repetitive tasks.
- Conditions
- Stroke, Depression, Splints
- Trial name
- Randomized (NCT06569654)
- Testing
- Saebo splint
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Ischemic Stroke, Acute, Active Malignancies
A Trial of Edaravone Dexborneol in Acute Ischemic Stroke With Active Malignancy
This multicenter randomized controlled trial aims to evaluate the efficacy and safety of edaravone dexborneol injection in patients with acute ischemic stroke (AIS) complicated by active malignancies.
- Trial name
- PRECISE AM (NCT07091994)
- Testing
- edaravone dexborneol injection, Standard therapeutic protocol
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Multiple Sclerosis
Acute Effects of Walking Exercise on Brain Functioning in Multiple Sclerosis
The project will involve a within-subjects, repeated-measures research design. Participants will initially be screened for relevant inclusion/exclusion criteria for maximizing safety of participating in an exercise study.
- Trial name
- PRIMERS (NCT06233370)
- Testing
- Moderate intensity walking exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Dementia
Dementia and Disability Simulation for College Nursing Students' Senior Activity Facilitation Skills
This study aims to evaluate the effectiveness of a dementia and disability simulation (DDS) program on dementia knowledge, attitude, empathy, and activity design skills for seniors among college nursing students.
- Trial name
- NCT06040294
- Testing
- DDS program, dementia course with no DDS
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tzu Chi University
Glioblastoma Multiforme of Brain, Brain Cancer
The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors
Glioblastoma patients are confronted with a debilitating disease associated with a low survival rate and poor quality of life. The goal of this study will be to reach a largely underrepresented population in the exercise…
- Trial name
- RESIST (NCT05116137)
- Testing
- Circuit-based resistance exercise (CRT)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Nova Scotia Health Authority
Stroke
Impact of Active Breathing Exercises on Respiratory Rhythm Disorders in Stroke Patients
The goal of this clinical trial is to explore The Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder.
- Trial name
- NCT06328803
- Testing
- Rehabilitation training, Active Breathing Exercises
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Parkinson Disease
Impact of Intensive Outpatient Rehabilitation on Non-Motor Patient-Reported Outcomes in Parkinson's Disease (INTENSO)
This historical cohort study aims to evaluate the impact of different intensity rehabilitation protocols on the short and medium-term severity of non-motor symptoms in patients with Parkinson's Disease.
- Trial name
- INTENSO (NCT06695286)
- Testing
- Multimodal rehabilitation training at high intensity, Multimodal rehabilitation training at low intensity
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Università Politecnica delle Marche
Alzheimer Disease, Mild Cognitive Impairment
Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI)
The proposed study is designed to evaluate the performance of the ALTOIDA™ System as a tool to assist physicians in diagnosing Alzheimer's Disease (AD) in real-world clinical settings.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Memory Disorders, Cognitive Impairment
- Trial name
- AltoidaML (NCT02843529)
- Testing
- Altoida: neuropsychological, MRI, EEG and CSF biomarkers
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Altoida
Exercise, ADHD
Exercise Enhances Brain Function in Attention-deficit/Hyperactivity Disorder (ADHD)
The aim of the study was to investigate the different effects of exercise types on inhibitory control in children with attention-deficit/ hyperactivity disorder.
- Conditions
- Exercise, ADHD, Executive Dysfunction
- Trial name
- NCT05016102
- Testing
- Exercise type
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Probiotics, Gut Microbiota
Probiotic Effects on the Microbe-brain-gut Interaction and Brain Activity During Stress Tasks in Healthy Subjects
The aim of this study is to determine if and how the "Probiotic Product" affects functional brain responses in healthy subjects during an emotional- and arithmetic stress task, respectively and in terms of microbe-brain-gut…
- Conditions
- Probiotics, Gut Microbiota, Emotional Stress, Magnetic Resonance Imaging
- Trial name
- NCT03615651
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Mild Traumatic Brain Injury
Treatment Optimization of Brain-injured Warfighters
Prescribed sub-symptomatic adaptable exercise treatment (SAET) is a potential solution that promotes recovery needs following a TBI.
- Trial name
- (TOBI-SET) (NCT06561100)
- Testing
- Sub-symptomatic Adaptable Exercise Treatment (SAET), Stretching Control Group (SCG)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Stroke
The Effects of Telerehabilitation-Based Spinal Stabilization Exercises in Stroke Patients
Stroke is a disease that causes sudden focal neurologic function loss lasting longer than 24 hours due to infarction or hemorrhage in relevant part of the central nervous system.
- Trial name
- NCT05306522
- Testing
- Spinal stabilization exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
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