Clinical trials: Brain Activity
Lateralization of the Brain Hemispheres
Effect of Handedness on Electromyographic Activity of Hand Muscles and Nerve Conduction Velocity During Use Mobil Phone in School Age Children
Asymmetries in both physiology and anatomy at different levels of the central nervous system, which controls the upper extremities, are well-established.
- Trial name
- NCT06497179
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- MTI University
Aortic Valve Stenosis
Anticoagulant Versus Dual Antiplatelet Therapy for Preventing Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement
This trial is to compare the efficacy of NOAC(Novel Oral Anticoagulants) with edoxaban vs. dual antiplatelet therapy (DAPT) for prevention of leaflet thrombosis (documented by cardiac CT imaging) and cerebral embolization…
- Trial name
- ADAPT-TAVR (NCT03284827)
- Testing
- NOAC, DAPT
- Where
- 5 sites in Hong Kong, South Korea and 1 more
- Volunteers
- 235 people
- Sponsor
- Duk-Woo Park, MD
Insulin Sensitivity
The Importance of Insulin Action in the Brain for the Immune System During Physical Activity
The goal of this clinical trial is to clarify the interaction of central insulin action and physical activity with the immune system. Therefore, participants will undergo bicycle spiroergometer tests.
- Trial name
- NCT06552130
- Testing
- Spiroergometer test with intranasal insulin spray
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Bronchial Carcinoma, Esophageal Carcinoma
Randomised Trial Evaluating the Benefit of a Fitness Tracker Based Workout During Radiotherapy
Evaluation of the impact of an activity tracker based fitness programme on the Qualitiy of Life after oncological therapy.
- Conditions
- Bronchial Carcinoma, Esophageal Carcinoma, Tumor of the Brain, Head and Neck Cancer
- Trial name
- OnkoFit II (NCT04517019)
- Testing
- Fitness tracker based activity training for Arm A and B. Booklet "physical training, exercise and cancer" and an introduction about physical activity during cancer therapy for Arm A, B, C
- Where
- Germany
- Volunteers
- 201 people
- Sponsor
- University Hospital Tuebingen
Parkinson Disease, Parkinson Disease, Idiopathic
Step Up to PD: A Community-based Walking Program for People With Parkinson's Disease
This study will investigate the feasibility of a 6-month community walking program for people with Parkinson's disease (PD) and their care partners in greater Saint Louis, Missouri region.
- Trial name
- NCT06859528
- Testing
- Community Walking Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- St. Louis University
Parkinson's Disease
Dexmedetomidine vs Propofol on the Recordings of Deep Brain Activity Measured Through Implanted Stimulators
This clinical trial has been designed to study and compare changes in deep brain activity (field potentials) in Parkinson's disease (PD) patients while awake, and during sedation with dexmedetomidine or propofol.
- Trial name
- DEXPROPAR (NCT02256319)
- Testing
- Dexmedetomidine, Propofol
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Epilepsy, Epilepsy in Youth
Adapting the STRW Intervention for Adolescents and Young Adults With Epilepsy (ARGOS)
The goal of this clinical trial is to learn if a telehealth intervention (Surviving and Thriving in the Real World; STRW) is helpful to improve daily living skills for teens and young adults with epilepsy.
- Conditions
- Epilepsy, Epilepsy in Youth, Activities, Daily Living
- Trial name
- ARGOS (NCT07676539)
- Testing
- Surviving and Thriving in the Real World
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Stroke
Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA)
The purpose of this RCT is to examine the efficacy of the Group Lifestyle Balance (GLB) program adapted for people with stroke (CVA) on primary (weight) and secondary outcomes at 3, 6, 12 months from enrollment into the program.
- Trial name
- GLB-CVA (NCT03873467)
- Testing
- Group Lifestyle Balance, Usual Care
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Baylor Research Institute
Parkinson's Disease
Efficacy and Safety of BIA 9-1067 in Idiopathic Parkinson's Disease Patients With "Wearing-off" Phenomenon
This study aims to demonstrate the efficacy and safety of BIA 9-1067, compared with entacapone or placebo, when administered with the existing treatment of L-DOPA plus a Dopa Decarboxylase Inhibitor (DDCI), in patients with…
- Trial name
- NCT01568073
- Testing
- BIA 9-1067, Entacapone, Levodopa
- Where
- Portugal
- Volunteers
- 600 people
- Sponsor
- Bial - Portela C S.A.
Hemiplegic Cerebral Palsy
Adapted Physical Activities in Hemiplegic Cerebral Palsy
The rehabilitation process is critical for people with disabilities, and it appears reasonable to predict that adaptive physical activity will become an important instrument for holistic development in a human rights perspective…
- Trial name
- NCT06459505
- Testing
- Routine or standard Physical Therapy, Adapted Physical Activity
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Concussion, Brain
The Influence of Prescribed Exercise on Pain Related Fear Following Concussion in Collegiate Athletes
The goal of this clinical trial is to compare the effects of acute aerobic exercise at two different intensities on psychological measures, symptomology, and time to symptom free in collegiate student athletes with concussion.
- Trial name
- NCT06246669
- Testing
- Treadmill Walking
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Virginia
Cerebral Palsy (CP), Malnutrition in Children
Assessment of Nutritional Status Using Mid-Upper Arm Circumference Z-Score in Children With Cerebral Palsy
Children with cerebral palsy are at increased risk of malnutrition due to motor impairment, feeding difficulties, and chronic health problems.
- Trial name
- NCT07351695
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Muğla Sıtkı Koçman University
Parkinson Disease
Effect of Aerobic Training on Oxidative Stress Markers in Patients With Parkinson's Disease
Parkinson's disease is a chronic, neurodegenerative disorder characterized with the loss of dopamine-producing neurons. This loss is likely to be related with several environmental and genetic factors.
- Trial name
- NCT05511402
- Testing
- Exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Saglik Bilimleri Universitesi
Phenylketonuria (PKU)
Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria
This is a Phase 3 open-label randomized controlled study enrolling approximately 54 adolescents with PKU. The study is designed to assess the safety and efficacy of pegvaliase injections.
- Trial name
- PEGASUS (NCT05270837)
- Testing
- Pegvaliase, Diet Only
- Where
- 16 sites in United States, Germany
- Volunteers
- 55 people
- Sponsor
- BioMarin Pharmaceutical
Alzheimer's Disease, Seizures
Seizure Activity in Alzheimer's Disease
The main purpose of this research project is to study how seizure-like activity affects the blood flow in the brain of patients with Alzheimer's disease (AD).
- Trial name
- NCT01554683
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Beth Israel Deaconess Medical Center
Brain Tumour, Metastatic Cancer
Rurality Adapted Physical Activity Sport Health
Physical activity (PA) has been an integral part of non-drug therapy since the early 2010s. This supportive care is likely to reduce fatigue and improve the quality of life of patients during and after the cancer treatment phase.
- Trial name
- RAPASS (NCT05981170)
- Testing
- Adapted physical activity at home
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Institut Cancerologie de l'Ouest
Cerebral Palsy
The Effects of Neurodevelopmental Therapy on Feeding and Swallowing.
Our study is planned to investigate the effects of neck and trunk stabilization exercises, which are structured from Neurodevelopmental therapy method-Bobath concept (NDT-B) principles, on feeding and swallowing activity in…
- Trial name
- NCT04403113
- Testing
- Structured neck and trunk stabilization exercises, Feeding and oral motor intervention strategies, Caregiver training related to feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Concussion, Brain
Salivary Biomarkers for Concussion Recovery
The overarching purpose of this proposed research is to determine whether BDNF and/or specific miRNAs can serve as biomarkers for recovery from a concussion during prescribed exercise.
- Trial name
- NCT05379920
- Testing
- High Volume Aerobic Exercise, Low Volume Aerobic Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Postcardiac Arrest, Pulseless Electrical Activity
Study of Survivors of Different Types of Cardiac Arrest and Their Neurological Recovery
After successful resuscitation from certain types of cardiac arrest, total body cooling is now a well established treatment that improves the chances of the brain recovering.
- Conditions
- Postcardiac Arrest, Pulseless Electrical Activity, Asystole
- Trial name
- NCT02033720
- Testing
- No treatment, Therapeutic hypothermia
- Where
- 2 sites in Canada
- Volunteers
- 400 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Parkinson Disease
Brain Activity During Gait in Parkinson's
Lay Summary: Walking problems, such as slow and short steps, are very common in Parkinson's disease and lead to increased falls risk, as well as reduced mobility and quality of life.
- Trial name
- BARC-PD (NCT04863560)
- Testing
- Auditory Cueing, Visual Cueing, tactile Cueing
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 80 people
- Sponsor
- Northumbria University
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