Clinical trials: Brain Activity
Agitation in Patients With Dementia of the Alzheimer's Type
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
This study was conducted to evaluate the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) compared to placebo for the treatment of agitation in participants with…
- Trial name
- NCT04464564
- Testing
- AVP-786
- Where
- 106 sites in United States, Belgium and 11 more
- Volunteers
- 241 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Stroke, Exercise
Addressing Arm Non-use by Encouraging Idle-time Activity During Early Recovery From Stroke
This project evaluates the feasibility of using custom wearable technology and associated procedures to increase activity of the more-involved upper extremity during the earliest stages of recovery from stroke by increasing the…
- Trial name
- NCT05900999
- Testing
- Feasibility of idle time exercise
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Marquette University
Stroke, Deficit in Manual Activities
Improving Bi-manual Activities in Stroke Patients With Application of Neuro-stimulation
Noninvasive brain stimulations (NIBS) will be used in healthy volunteers and in chronic stroke patients to improve bimanual activities and motor learning.
- Trial name
- NCT02308852
- Testing
- tDCS
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Cluster Headache
A Close Examination of Patient Experiences in Cluster Headache Clinical Research
Historically, participation in clinical studies is highly skewed towards particular demographic groups of people. This research will invite several participants to gather a wide range of information on clinical trial experiences…
- Trial name
- NCT05978258
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Involutional Depression, Anxiety Disorders
MRI Study of Brain Activity and Risk for Depression in Adolescents
Anxiety in children of parents with major depressive disorder (MDD) poses a particularly high risk for later-life MDD. In adults, MDD involves dysfunction in prefrontal brain regions that regulate attention to emotional stimuli.
- Trial name
- NCT00047944
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Institute of Mental Health (NIMH)
Stroke, Motor Activity
SALGOT; Stroke Arm Longitudinal Study at the University of GOThenburg
Stroke is the most common cause for motor disability in the grown-up population in the Western world. In Sweden > 80 % are above 65 years of age at onset (1).Areas in the brain, controlling the movement in the upper extremity…
- Trial name
- SALGOT (NCT01115348)
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Göteborg University
Exercise, Parkinson's Disease
The Effects of Treadmill Versus Agility Training in Parkinson's Disease
Aim: To determine the Responsiveness of the iMOBILITY in response to intensive physical therapy exercise programs. (Is it sensitive to change?) Although exercise is thought to be the most effective intervention for balance and…
- Trial name
- NCT00982709
- Testing
- Aerobic vs. Agility Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Stroke
Follow-up of Patients' Physical Activity in Post-hospitalization
Physical exercise has been identified as a major item of many affecting many chronic diseases and stroke rehabilitation. It contributes to an improvement in the quality of life and to a decrease in the current treatment…
- Trial name
- TICAA'DOM (NCT01822938)
- Testing
- incentive program for physical activity
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Limoges
Stroke
The Effect of Activity Feedback Enabled by Smart Watches During In-patient Stroke Rehabilitation
The amount of activity completed by individuals within rehabilitation programs, even when units are well staffed, is often far below that required for optimal stroke rehabilitation, and is not individually adapted on a day-to-day…
- Trial name
- NCT02587585
- Testing
- Feedback against tailored target, No feedback
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
Healthy
Acute Effect of Three Neuroactive Drugs Measured by Magnetoencephalography (MEG), Electroencephalography (EEG) and the Synchronous Neural Interaction Test
This placebo-controlled crossover study is intended to measure the effect of three, common neuroactive medications on brain activity measured by magnetoencephalography (MEG) and electroencephalography (EEG).
- Trial name
- NCT00972985
- Testing
- modafinil, methylphenidate, lorazepam
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Orasi Medical, Inc.
Headache, Migraine, Persistent Post Traumatic Headache
Validating a Modified COMPASS 31questionnaire for Treatment Outcomes
Eligible participants will complete the COMPASS 31 (year), modified COMPASS 31(one month) and the NSI (one month) questionnaires at baseline and complete the modified COMPASS 31 and the NSI after usual care of treatment.
- Conditions
- Headache, Migraine, Persistent Post Traumatic Headache, Cervicogenic Headache
- Trial name
- COMPASS (NCT05302479)
- Testing
- COMPASS 31 questionnaire
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Brooke Army Medical Center
Stroke, Cerebrovascular Accident
Fluoxetine Opens Window to Improve Motor Recovery After Stroke
The FLOW trial is a randomized placebo-controlled trial analyzing the effect of coupling an anti-depressant, fluoxetine (Prozac), and exercise to improve motor recovery following a stroke.
- Conditions
- Stroke, Cerebrovascular Accident, Cerebral Infarction, Brain Infarction
- Trial name
- FLOW (NCT03448159)
- Testing
- Fluoxetine Hydrochloride, Exercise Program
- Where
- 8 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea
Effects of Exercise Training on Cognitive Performance and Sympathetic Activity in Obstructive Sleep Apnea
Abstract Obstructive sleep apnea syndrome (OSA) is characterized by complete or partial collapse of a narrowed pharynx and it's associated with reduction in cerebral blood flow, cardiovascular disease, and neuropsychological…
- Trial name
- NCT02289625
- Testing
- Exercise Training
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Cerebral Palsy
Gross Motor Function and Living Skills in CP
Cerebral palsy (CP) is non-progressive disorder, which undergoes mishap to the developing brain and it affects a person's ability to move and maintain balance and posture.
- Trial name
- NCT06460779
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Intellectual Disability, Serious Mental Illness
Virtual Reality Task-Oriented Physical Activity in Adults With Mental Disabilities
The goal of this clinical study was to examine the effects of virtual reality task-oriented physical activity on physical and task performance and brain activity in adults with mental disabilities.
- Trial name
- NCT07844525
- Testing
- Virtual Reality Task-Oriented Physical Activity Training
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- National Taiwan Normal University
Colorectal Cancer, Older Adults (60 - 85 Years Old)
Chemo Brain Prehab Project
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin.
- Conditions
- Colorectal Cancer, Older Adults (60 - 85 Years Old), Physically Inactive, Chemotherapy
- Trial name
- CHEMOBRAIN (NCT07341217)
- Testing
- Exercise Prehabilitation, Multivitamins, Standard Care (in control arm)
- Where
- 4 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- Dr. Chris Gaffney
Cognition Disorders in Old Age, Physical Activity
Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment
Scientific evidence regarding the effects of Brain Gym®, on people with cognitive impairment is scarce. This study aimed at comparing the effects of a program based on Brain Gym® exercises against a fitness exercise program on…
- Trial name
- NCT03368482
- Testing
- Brain Gym Exercises, Standard exercise program for institutionalized older adults.
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Vigo
Aging Disorder, Parkinson Disease
Contribution of Virtual Reality and Modelling in Falling Risk Assessment in Elderly and Parkinson's Disease Patients
The process of ageing affects at the same time the sensory, cognitive and driving functions. Furthermore, ageing is often accompanied by pathologies increasing the effects of the senescence.
- Trial name
- PrévSim (NCT03848897)
- Testing
- Metrology of motor behavior
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Physical Disability, Cognitive Impairment
Improving Aging in Place in Subsidized Housing
This pilot study will evaluate the feasibility and preliminary effectiveness of an adapted version of the Function Focused Care intervention, delivered by telephone, for improving aging in place for older adults living in…
- Conditions
- Physical Disability, Cognitive Impairment, Physical Activity
- Trial name
- NCT04212442
- Testing
- Independent Living Program for Affordable Housing.
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Human Brain Activity
Effects of rTMS on Human Brain Activity Measured With fMRI
This project investigates the effects of repetitive transcranial magnetic stimulation (rTMS) on neural circuits as a function of spatiotemporal parameters and brain state in order to better understand why the method works and how…
- Trial name
- NCT03259568
- Testing
- Repetitive TMS
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Duke University
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