Clinical trials: Brain Disorder
Stroke, Healthy
Motor Learning in Stroke Patients and Healthy Volunteers
This study will try to elucidate learning processes associated with motor training in the weak arm of stroke patients compared with healthy controls.
- Trial name
- NCT00021710
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Headache Disorders, Primary, Migraine
Trigeminal Brainstem Mapping
To what extent the somatotopy of the 3 branches of the trigeminal nerve (V1,V2,V3) as well as the greater occipital nerve (GON) in the brainstem but also in the thalamus and the insula can be mapped using functional imaging and…
- Trial name
- NCT03999060
- Testing
- Electric Current Stimulation
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Japanese Encephalitis
Seroepidemiology of Japanese Encephalitis Virus Infection in Hualien, Taiwan
Japanese encephalitis (JE) is one of important zoonotic infectious diseases in Taiwan. JE caused by Japanese encephalitis virus (JEV) which transmitted by Culex tritaeniorhynchus and used swine as amplifying host.
- Trial name
- NCT01163123
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Mennonite Christian Hospital
Autism Spectrum Disorder, Traumatic Brain Injury
Using Virtual Reality and Robotics Technologies for Vocational Evaluation, Training and Placement
Using Virtual Reality and Robotics Technologies for Vocational Evaluation, Training and Placement (VR4VR) is a project that incorporates Virtual Reality into job training to increase job opportunities for people who have physical…
- Trial name
- VR4VR (NCT02498262)
- Testing
- Virtual Reality System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Posttraumatic Stress Disorder, PTSD
TDCS-Augmented Prolonged Exposure Therapy
The purpose of this study is to determine the effects of a brain stimulation technique known as transcranial direct current stimulation, or tDCS, on the benefits of Prolonged Exposure therapy, or PE, which is an effective…
- Conditions
- Posttraumatic Stress Disorder, PTSD, Anxiety, Depression
- Trial name
- NCT04327362
- Testing
- Transcranial Direct Current Stimulation (tDCS), Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
COVID-19
Brain Function Changes Following COVID-19 Infection
The global COVID-19 pandemic has now led to millions of infections worldwide. It produces long-lasting changes in the general physiology of multiple organs, including the brain.
- Trial name
- NCT05961618
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Alzheimer Disease
Meaningful Aspects of Health for Adults With Dementia, Their Care Partners and Healthcare Practitioners
The aim of this study is to describe, using a non-interventional survey, the relevant aspects of health in adults with ADRD for the patients themselves, their carers and healthcare professionals.
- Trial name
- DiME (NCT06242574)
- Testing
- Survey
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Glioblastoma Multiforme, Anaplastic Astrocytoma
Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma
This study will offer a safe treatment for patients with relapsing recurring glioblastoma (GBM) or anaplastic astrocytoma (AA). The trial will test the hypothesis that Erlotinib (Tarceva, OSI-774) can be safely used up to a dose…
- Trial name
- NCT00301418
- Testing
- Erlotinib
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood
Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders
This study aims to investigate whether a parent-based treatment for childhood anxiety disorders engages child brain circuitry implicated in children's reliance on parents to reduce anxiety (R61), and whether change in child brain…
- Conditions
- Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder
- Trial name
- NCT03585010
- Testing
- Supportive Parenting for Anxious Childhood Emotions, Parent Educational Support, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Yale University
Epilepsy
Women With Epilepsy: Pregnancy Outcomes and Deliveries
This is a three-center prospective case-control study to examine the patterns of fertility among women with epilepsy (WWE) compared to an age-matched group of women without epilepsy (WWoE).
- Trial name
- WEPOD (NCT01259310)
- Where
- 3 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Major Depressive Disorder
Real-time Biofeedback With 7-Tesla MRI for Treatment of Depression
Previous research has shown that modulation of a brain region in rodents, the ventral tegmental area (VTA), improves depressive symptoms.
- Trial name
- Biofeedback (NCT04138680)
- Testing
- Active Biofeedback
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypoxic-Ischemic Encephalopathy, Pain
The Effect of Maternal Scent and Knitted Octopus Application on Pain in Infants Diagnosed With Neonatal Asphyxia and Receiving Therapeutic Hypothermia Treatment
This study was designed to determine the effects of maternal scent and knitted octopus application on pain in infants born with asphyxia beyond 36 weeks' gestation and receiving Therapeutic Hypothermia (TH) treatment in the…
- Trial name
- Pain in HIE (NCT07526233)
- Testing
- scent
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Alev Sivasli
Atrial Fibrillation
Improving the Quality of Care for Atrial Fibrillation by Promoting Patient-Centered Decision Making
The primary aim of this proposal is to determine the effectiveness of a decision support tool on improving the process of shared decision-making for treatment on nonvalvular atrial fibrillation (NVAF) compared to receipt of usual…
- Trial name
- AFIB (NCT00829478)
- Testing
- Decision Aid for Atrial Fibrillation, Usual Care
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- VA Connecticut Healthcare System
Normal Physiology, fMRI
The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans
Background: Two areas on the surface of the brain, the dorsolateral prefrontal cortex (DLPFC) and motor cortex (MC), play a key role during learning.
- Trial name
- NCT01260740
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Neurodevelopmental Disorders, Child Behavior
Neurodevelopmental Outcome After Prenatal Anesthesia
In 2016, the US Food and Drug Administration raised concerns about the potential negative effects of anesthesia exposure on neurodevelopment in children during pregnancy or before the age of three.
- Trial name
- NCT06052878
- Testing
- Parental telephone interview with standardized parental questionnaire from the "Behaviour Rating Inventory of Executive Function" (BRIEF), Parental questionnaire about their child's cognitive functioning in their daily life and medical history.
- Where
- France
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Cerebral Small Vessel Disease
Biomarkers, Risk Assessment, Imaging, and Neurodegeneration in Cerebral Small Vessel Disease (BRAIN-CSVD)
The BRAIN-CSVD study is a single-center prospective cohort study focusing on cerebral small vessel disease (CSVD).Patients enrolled in this research will undergo assessments for vascular risk factors, cognitive and other…
- Trial name
- BRAIN-CSVD (NCT07093515)
- Testing
- No intervention
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhejiang Hospital
Concussion
Recent Experiences With Concussions
College athletes will be recruited to complete a voluntary online survey that will take approximately 10 minutes. In this survey, they will answer a series of questions related to the concussion symptoms they have experienced in…
- Trial name
- NCT02626650
- Testing
- Symptom elicitiation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Epilepsy, Tonic-Clonic
Topiramate Bioequivalence Study Brazil - Fast
This study is prospective, open-label, randomized, crossover, single dose, with 02 treatments, 02 sequences and 02 periods. The volunteers received, in each period, the reference or the test formulation, according to the…
- Trial name
- NCT01439438
- Testing
- Topiramate coated tablet, Topamax® coated tablet
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Mild Traumatic Brain Injury (mTBI), Brain Injury
A Feasibility Study in Combat Athletes With Mild Traumatic Brain Injury
The use of Hyberbaric Oxygen Therapy (HBOT) would be a new treatment plan rather than conventional rest. If effective, this new use technology would add to the clinical treatment among mild traumatic brain injury (mTBI) patients.
- Conditions
- Mild Traumatic Brain Injury (mTBI), Brain Injury, Concussion
- Trial name
- NCT06901310
- Testing
- Hyberbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Michael Harl
Stroke
Stroke Rehabilitation Program Based on a Powered Lower Extremity Exoskeleton in Chile
This research will study the effects of a rehabilitation program assisted by a powered lower extremity exoskeleton in patients after stroke.
- Trial name
- NCT04228224
- Testing
- Robot-assisted training with a lower extremity powered exoskeleton (H3 Exoskeleton, Spain), Conventional gait rehabilitation
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
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