Clinical trials: Brain Disorder
Myocardial Infarction (MI), Stroke
Smartphone Application to PREDICT Real-Time Cardiovascular Risk for Heart Attack and Stroke
To assess the diagnostic accuracy of a smartphone application in predicting heart attack or stroke within 3-4 days in high-risk patients.
- Trial name
- PREDICT-HS (NCT07735338)
- Testing
- Smartphone application Antshrike
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Stanford University
Phenylketonuria, Behavior and Behavior Mechanisms
Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders
This observational study seeks to establish evidence: 1. that physiologic changes, unrelated to effect on the Phenylalanine Hydroxylase (PAH) enzyme, occur in Phenylketonuria (PKU) patients who are treated with sapropterin…
- Conditions
- Phenylketonuria, Behavior and Behavior Mechanisms, PAH Gene Expression
- Trial name
- IST (NCT01274026)
- Testing
- sapropterin dihydrochloride
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Frontal Lobe Epilepsies
Co-operative Behavior and Decision-making in Frontal Lobe Epilepsy
Epilepsy is a frequent neurological disorder with about a third of patients having seizures despite treatment. At least some of these seizures can be linked to a low compliance and therapy adherence of patients.
- Trial name
- NCT02441478
- Testing
- functional magnetic resonance imaging exam
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Alzheimer Disease
A Study of Two Doses of 18F-AV-45 in Alzheimer's Disease and Healthy Volunteers
This study will test two different doses of florbetapir F 18 to determine which dose is best to image amyloid plaques in the brains of Alzheimer's Disease (AD) patients using a positron emission tomography (PET) scanner.
- Trial name
- NCT01565330
- Testing
- florbetapir F 18
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Metabolic Syndrome X, Diabetes Mellitus Type 2
Metabolic Syndrome and Related Diseases in Healthcare Workers
This study aims to investigate the incidence and prevalence of metabolic syndrome and metabolism-related diseases among healthcare workers, identify potential risk factors for these diseases, evaluate the control status of these…
- Conditions
- Metabolic Syndrome X, Diabetes Mellitus Type 2, Hypertension, Hyperlipidemia
- Trial name
- NCT06543706
- Where
- China
- Volunteers
- 7,432 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Huntington Disease
Behavioural Problems in Huntington Disease : Analysis and Enhancement of Caregiver and Patient Experience
The study hypothesis is that caregivers experience allows them to develop a lot of knowledge and know-how about behavioural problems in Huntington Disease and its consequences.
- Trial name
- HUNTEXPERT (NCT02218567)
- Testing
- questionnaire qualilty of life, psychological interview, psychological tests
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Obesity, Overweight
Metabolic Effect of New Foods Through Gut-brain Axis
A diet high in easily obtained energy-dense foods leads to the problems of overweight and obesity common in the developed world. Foods enriched with fiber or bitter compounds may increase satiety and decrease energy intake.
- Trial name
- CHECKMATE (NCT01851304)
- Testing
- Satiety of breads, Satiety of puddings
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Federico II University
Alzheimer's Disease
The Detection of Early Dementia With the Digital Game Memory
The investigators are going to test if it is possible to detect early dementia with the digital game "memory". The investigators are going to test 15 healthy people and 15 patients with early dementia.
- Trial name
- NCT02041728
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson, Parkinson Disease
Virtual Reality and Fear of Falling in Parkinson's Disease
Background: Falls are common in elderly individuals and those with neurological conditions like Parkinson's disease. Parkinson's disease causes postural instability and mobility issues that lead to falls and reduced quality of…
- Conditions
- Parkinson, Parkinson Disease, Parkinson's Disease and Parkinsonism
- Trial name
- NCT05931692
- Testing
- Virtual reality, Electroencephalogram, Electromyography
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Dementia
The Family Caregiver Training Program for Caregivers of People With Dementia
The purpose of this study is to examine the effectiveness of the Family Caregiver Training Program for caregivers of people with dementia, using a pretest posttest randomized control trial with 3-month follow-up.
- Trial name
- NCT02649244
- Testing
- The Family Caregiver Training Program
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Growth Hormone Deficiency
304-C03/L3301n: Effects of Growth Hormone on Glucose and Protein Metabolism in Children With Growth Hormone Deficiency
The purpose of the proposed study is to investigate the effects of rhGH treatment on glucose, protein and fat metabolism in GHD children.
- Trial name
- NCT00362063
- Testing
- growth hormone (Nutropin)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Mild Cognitive Impairment
Neurotrack Test Validation Protocol
This protocol describes a study to validate Neurotrack's visual paired comparison task, aimed at early detection and monitoring of memory impairment.
- Trial name
- NCT02608021
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Attention Deficit Hyperactivity Disorder
Magnetic Resonance Imaging of Brain Development in Attention Deficit Hyperactivity Disorder
The primary purpose of this study is to investigate brain whether ADHD represents a disruption or a delay of brain development. Children and adolescents both with and without ADHD are asked to participate in several MRI sessions…
- Trial name
- NCT00143767
- Where
- Netherlands
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Mild Cognitive Impairment (MCI)
Cognitive-Frailty Gait Biomechanics for Early Dementia Detection
The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults.
- Trial name
- gait dementia (NCT07448909)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Stroke, Acute, TIA
Somatic Dysfunction in Patients With Acute Cerebrovascular Disease
The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in…
- Conditions
- Stroke, Acute, TIA, Reproducibility of Results, Osteopathic Manipulation
- Trial name
- SOMADC-AC (NCT06605014)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Acromegaly, Pituitary Tumor
The Observational Study of Growth Hormone-secreting Pituitary Tumors
The major purpose of this study is to evaluate the changes of multiple organs in patients with growth hormone-secreting pituitary tumors before and after surgery.
- Trial name
- NCT01368133
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Obesity
Effects of Macronutrient Diet on Brain Activity
This study will evaluate the effect of macronutrient diets on brain activity in homeostatic and mesolimbic reward regions.
- Trial name
- NCT02300857
- Testing
- Low carbohydrate diet, Moderate carbohydrate diet, High carbohydrate diet
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Horner's Syndrome
Clinical Efficacy of Supraclavicular Block for Arthroscopic Shoulder Surgery
The aim of this study is to compare the efficacy of supraclavicular and interscalene brachial plexus blocks in the patients undergoing arthroscopic shoulder surgery.
- Trial name
- NCT01958801
- Testing
- Supraclavicular block, Interscalene block
- Where
- South Korea
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Daegu Catholic University Medical Center
Autism Spectrum Disorder
Measuring Brain Inflammation in Autism
Autism spectrum disorders (ASD) are highly disabling, persistent neurodevelopmental disorders. There are no available treatments for core symptoms of ASD or biologically-based clinical biomarkers.
- Trial name
- NCT03117530
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
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