Clinical trials: Brain Excitation
Behavioral Flexibility, Healthy Volunteers
Flexibility, Alcohol Misuse, and Excitation
The goal of this study is to learn whether a single non-invasive brain stimulation alpha-transcranial alternating current stimulation (alpha-tACS) session changes measures of excitability in the prefrontal cortex.
- Conditions
- Behavioral Flexibility, Healthy Volunteers, High Risk Alcohol Use
- Trial name
- FLAME (NCT06634771)
- Testing
- 10 Hz transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Epilepsy
Effect of Vagal Nerve Stimulation on Gastric Motor Functions
The specific aim of this study is to compare simultaneous assessment of gastric emptying and gastric accommodation in response to a caloric meal In patients who have previously undergone activation of left cervical VNS for the…
- Trial name
- NCT06038929
- Testing
- Vagal nerve stimulant
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Mayo Clinic
Healthy Volunteers, Brain Excitation
Methods to Enhance Transcranial Direct Stimulation (tDCS)
tDCS has been shown to be an effective treatment for depression. However, tDCS is a relatively new clinical tool and more needs to be understood about its use.
- Trial name
- NCT01135953
- Testing
- Transcranial Direct Current Stimulation (tDCS), Transcranial direct Stimulation (tDCS) and D-cycloserine
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Autism Spectrum Disorder
Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder
This study investigates brain response to single acute dose of cannabidiol, cannabidivarin, and placebo in healthy men with and without autism spectrum disorder
- Trial name
- NCT03537950
- Testing
- PLC, CBD, CBDV
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- King's College London
Drug Resistant Epilepsy, Temporal Lobe Epilepsy
The GABAergic Inhibitory System in Drug Resistant Epilepsy
This study aims to investigate the effect of lovastatin on neurotransmission and neuroinflammation in patients with temporal lobe onset drug resistant epilepsy.
- Trial name
- NCT06789497
- Testing
- Lovastatin 60 MG
- Where
- Portugal
- Volunteers
- 5 people
- Sponsor
- University of Coimbra
Cerebrovascular Accident
Improving Arm Mobility and Use After Stroke
An individual suffering a stroke or other brain injury may lose function on one side of the body (partial paralysis). As the individual shifts activities to favor the unaffected side, the problem worsens.
- Trial name
- NCT00057018
- Testing
- Constraint-induced movement therapy
- Where
- 7 sites in United States
- Volunteers
- 229 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Novel Method for Transcranial Brain Stimulation
Phase Locked TRanscranial Electrical EXcitation
Transcranial current stimulation (tCS) has been extensively studied due to its potential of selectively stimulate brain regions in a non-invasive way.
- Trial name
- T-REEX (NCT05847829)
- Testing
- T-REEX algorithm
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stichting IMEC-NL
Epilepsy, Depressive Disorder
RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS
The acute and chronic effects of VNS stimulation on various on the autonomic nervous, cardiovascular, immune, and metabolic systems will be compared from noninvasive and minimally invasive physiological recordings and blood draws…
- Trial name
- NCT06143293
- Testing
- Vagus nerve stimulation device: acute and chronic administration of investigational vagus nerve stimulation parameters
- Where
- 7 sites in United States, Australia
- Volunteers
- 144 people
- Sponsor
- University of Minnesota