Clinical trials: Brain Health
Cerebral Palsy
HMB Cerebral Palsy Pilot Study
This is a pilot study of β-hydroxy-β-methylbutyrate (HMB) + Vitamin D3 supplementation in adolescents with cerebral palsy. The primary objective is to quantify safety, compliance, and acceptability of daily combined HMB + Vitamin…
- Trial name
- NCT05384951
- Testing
- HMB + Vitamin D3
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Gillette Children's Specialty Healthcare
Healthy Aging, Middle-aged and Older Adults
Peanut Butter and Brain Health
Healthy foods, including peanuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Trial name
- NCT07774546
- Testing
- Peanut butter
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Penn State University
Education, Dementia
Reuptake of an E-Learning Programme in General Practice
The evaluate the use and diffusion of an E-learning programme in Diagnostic Evaluation of Dementia among General Practitioners (GPs) in Denmark. The hypothesis are: 1. The GPs do not use the guided instructions 2.
- Trial name
- NCT00392483
- Where
- Denmark
- Volunteers
- 3,632 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Parkinson Disease
Quality-of-Life Index (Q-Index)
The main objective of this observational study is to use commonly-used connected objects (smartphones and smartwatches) to remotely assess and monitor the health-related quality of life (HrQoL) of people with Parkinson's disease…
- Trial name
- NCT06209502
- Where
- 4 sites in Belgium
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Koios Care
Dementia, Mild Cognitive Impairment
A Pilot Study for the Brain Health Support Program
Prior studies have shown that programs that focus on promoting brain health and managing lifestyle risks (such as poor diet, obesity, physical inactivity, sleep issues, loneliness) may help in preventing or lowering the risk of…
- Conditions
- Dementia, Mild Cognitive Impairment, Subjective Cognitive Impairment, Pre-dementia
- Trial name
- CTU BHSP-P (NCT05167045)
- Testing
- Brain Health PRO
- Where
- 3 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baycrest
Dementia, Abuse Client
Partnership in Safeguarding People With Dementia From Primary and Social Care Perspectives
"Adult safeguarding is everyone's responsibility". The Care Act 2014 makes safeguarding a legal duty. It provides local authorities and other agencies in England with a responsibility to protect adults with care and support needs…
- Conditions
- Dementia, Abuse Client, Neglect; Care, Malnutrition
- Trial name
- NCT05883527
- Testing
- Not applicable as not an intervention - PLwD and family/carers, Not applicable as not an intervention - HCP's
- Where
- 5 sites in United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Stroke, Psychological Well-Being
Aspirational Rehabilitation Coaching for Holistic Health (ARCH): A Pilot Pre-Post Experimental Study
The ARCH programme is a novel, strength-based, dyadic, multicomponent psychosocial intervention that blends together psychoeducation, psychosocial support and self-compassion practices to aid first-time stroke survivors and their…
- Conditions
- Stroke, Psychological Well-Being, Psychosocial Functioning
- Trial name
- NCT06596551
- Testing
- Pre-Post ARCH Intervention
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Aging, Cognitive Decline
Blood Flow Restriction and High-intense Resistance Training in Aging: Interactions Between Neuroplasticity and Muscle
BRAIN-M is a randomized controlled trial designed to examine the effects of a single bout or 12 weeks of blood-flow restriction training or high-intensity resistance training on cognitive function, brain health, muscular…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Frailty
- Trial name
- BRAIN-M (NCT05744167)
- Testing
- BFRT, MDRT
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Mental Health Wellness 1
Acute Effects of Physical Activity On Memory, Cognitive Performance and Brain Activity
The overall aim of the study is to investigate the effects of an acute bout of physical activity on cognitive performance and long-term memory in elementary school children.
- Trial name
- NCT03391505
- Testing
- Small-sided soccer game, Walking soccer game, Rest group watching soccer
- Where
- Denmark
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Mild Cognitive Impairment, Mild Dementia
Brain Health & the Microbiome
The GW SMHS supports research in complementary and integrative approaches to treatment of sickness and disease and for health promotion.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Alzheimer Disease 1
- Trial name
- bMicrobiome (NCT06039267)
- Testing
- Gut Microbiome Testing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- George Washington University
Brain Health, Gestational Hypertension
Brain Health in Midlife
The purpose of this study is to learn if hypertensive disorders during pregnancy affects brain health in midlife.
- Conditions
- Brain Health, Gestational Hypertension, Alzheimer Disease, Dementia
- Trial name
- ADORE BRAIN (NCT06640842)
- Testing
- A combination of various tests and biomarkers will be completed to understand the effect of hypertensive disorders of pregnancy on brain health in midlife.
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Dementia, Oral Hygiene
Oral Health, Bite Force and Dementia
Study aims: The primary aim is to identify influencing variables on oral hygiene / oral health and bite force in patients with dementia.
- Conditions
- Dementia, Oral Hygiene, Chewing Problem
- Trial name
- OrBiD (NCT03775772)
- Testing
- Oral Health, Bite Force
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Brain Health Retired Elite Athletes
Long-term Brain Health of Retired Professional Rugby Players, With a History of Concussion/Head Impact Exposure
There has been significant recent interest on the issue of brain health in athletes. Participation in sports is generally viewed as extremely positive.
- Trial name
- NCT03544346
- Testing
- Exploratory brain and general health assessment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Parkinsonian Disorders
Oral Health, Orofacial Function and Oral Health Care in Patients With Parkinson's Disease
Introduction: Problems with oral health (dental and oral diseases) as well as orofacial function (jaw opening, chewing and salivation problems) are significant challenges for many people with Parkinson's disease (PD).
- Trial name
- NCT05356845
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Stroke, Medication Adherence
Adherence to Medical Treatments for Telemedicine Patients
This study will test the feasibility of MedRem, a novel medication reminder and tracking system on wearable wrist devices, specifically with the Apple Watch 4.
- Trial name
- NCT04180475
- Testing
- MedRem application
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Brain Care Score, Exercise
An Exercise Intervention to Improve Overall Brain Health
The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a…
- Conditions
- Brain Care Score, Exercise, Hypertension, BMI
- Trial name
- NCT06035094
- Testing
- Exercise Intervention to improve overall Brain Health
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dementia
DemensiaKITA Mobile Health App to Improve Knowledge, Attitude, Practice and Reduce Burden Among Dementia Caregivers in Malaysia
Dementia is a growing health concern in Malaysia and places a heavy burden on family members who act as caregivers. Many caregivers struggle with limited knowledge, negative attitudes, and challenges in daily caregiving…
- Trial name
- DemensiaKITA (NCT07212894)
- Testing
- DemensiaKITA mobile health application, Usual Care
- Where
- Malaysia
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Stroke, Oral Disease
Oral Health and Vitamin D in Stroke Patients
Stroke is a common, serious and restrictive global health problem. Restricting the activities of daily living of stroke patients impairs patients' ability to pay attention to oral hygiene.
- Conditions
- Stroke, Oral Disease, D Vitamin Deficiency
- Trial name
- NCT05418335
- Testing
- Clinical examination, functional status evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Brain Health, Cognition
Exercise Effects on Cognition in School-Aged Children
Recent trends have identified decreasing levels of physical activity, fitness, and health in preadolescent children. Examining factors, such as physical activity behavior and aerobic fitness that positively influence cognitive…
- Conditions
- Brain Health, Cognition, Scholastic Achievement
- Trial name
- FITKids (NCT01334359)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign