Clinical trials: Brain Health Activities
Physical Inactivity
The Effect of Brain Breaks on People With Mental Health Problems
Regular physical activity (PA) and adopting an active lifestyle protect against non-communicable diseases such as diabetes, cardiovascular diseases, hypertension, obesity, and colon cancer in the general population.
- Trial name
- NCT05783674
- Testing
- Brain Breaks® Video Exercises, Posture training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istinye University
Traumatic Brain Injury, Exercise
AI-driven Personalized Exercise Feedback Program on Exercise Adherence in Traumatic Brain Injury
This study aims to develop and evaluate an AI-driven Personalized Exercise Feedback Program (AI-PEF) to enhance exercise adherence and health outcomes in mTBI patients.
- Conditions
- Traumatic Brain Injury, Exercise, AI (Artificial Intelligence), Digital Health
- Trial name
- NCT06817564
- Testing
- AI-PEF, Theory-based digital exercise, Active Control
- Volunteers
- 125 people
- Sponsor
- National Defense Medical Center, Taiwan
Healthy Adults
Acute Effects of Sitting and Physical Activity on Brain Health
The specific aim of this study is to understand how a working day composed of prolonged sitting, sitting regularly interrupted by light aerobic exercise or resistance exercise affects an important mechanism underpinning healthy…
- Trial name
- NCT04137211
- Testing
- Prolonged sitting with social break, Prolonged sitting with walk break, Prolonged sitting with simple resistance activities
- Where
- Sweden
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Cerebral Palsy
Participation to Life of Children With Cerebral Palsy
Cerebral Palsy (CP) defined as a group of permanent impairments that is originating from non-progressive disorders that develop in the immature brain. CP leads activity limitations of movement and posture development.
- Trial name
- PLCC (NCT03191695)
- Testing
- Assessment via questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Hacettepe University
Relapsing-Remitting Multiple Sclerosis
Behavior and Activity Monitoring in MS
The investigators propose to conduct a randomized 6-month intervention study comparing cognitive functioning in individuals with relapsing-remitting multiple sclerosis assigned to either a physical activity or an active…
- Trial name
- NCT03244696
- Testing
- Step Tracking, Water Tracking
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Ohio State University
Multiple Sclerosis
Exercise & Brain Health in MS
The purpose of this study is to learn more about multiple sclerosis (MS). The investigators are studying whether aerobic exercise is better than a stretching program at improving brain health in people with MS.
- Trial name
- NCT02263339
- Testing
- Aerobic Exercise, Stretching, Aerobic Exercise- Healthy Subjects
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Cerebral Palsy, Quality of Life
Health Related Lifestyle and Quality of Life in Children With Cerebral Palsy
The primary aim of this study is assessing physical activity, the quality of sleep and health related quality of life in children with cerebral palsy, and parenting stress of caregivers of the children with cerebral palsy in…
- Conditions
- Cerebral Palsy, Quality of Life, Physical Activity, Physical Disability
- Trial name
- NCT03277027
- Testing
- interventional study
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- The Catholic University of Korea
Stroke
Rehabkompassen® - a Patient-centered Digital Follow-up Tool in the Post-stroke Continuum of Care
Stroke is a leading cause of disability and with a heavy burden for the society. Despite the demands from 'Socialstyrelsen' of improving post-acute care, an effective structured follow-up to promote a patient-tailored…
- Trial name
- NCT04915027
- Testing
- a usual follow-up with Rehabkompassen®, a usual follow-up with Post-Stroke Checklist, i.e. without Rehabkompassen®
- Where
- Sweden
- Volunteers
- 1,106 people
- Sponsor
- Umeå University
Stroke, Physical Activity
Activating Behavior for Lasting Engagement After Stroke
Stroke survivors demonstrate high levels of sedentary behavior, placing them at risk for exacerbation of chronic health conditions. This may lead to recurrent stroke.
- Conditions
- Stroke, Physical Activity, Sedentary Lifestyle, Behavior, Health
- Trial name
- ABLE (NCT03305731)
- Testing
- Activating Behavior for Lasting Engagement
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Pittsburgh
Migraine Disorders, Exercise
Educational Video Program to Promote Physical Activity and Reduce Migraine Frequency in Adults With Migraine
The goal of this clinical trial is to learn if an educational video program can help reduce migraine frequency and improve migraine-related outcomes in adults with migraine.
- Conditions
- Migraine Disorders, Exercise, Health Education, Audiovisual Aids
- Trial name
- PA-MIG (NCT06993545)
- Testing
- Video-based educational program on physical activity for migraine management
- Where
- Portugal
- Volunteers
- 307 people
- Sponsor
- Universidade do Porto
COPD, Tetrahydrobiopterin Deficiency
O2 Transport and Utilization in Health and Lung Disease
Skeletal muscle dysfunction is a frequent and clinically relevant systemic manifestation of Chronic Pulmonary Obstructive Disease (COPD), which is still poorly understood.
- Conditions
- COPD, Tetrahydrobiopterin Deficiency, Oxidative Stress
- Trial name
- NCT04014712
- Testing
- Tetrahydrobiopterin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors
This longitudinal observational study examines how social health, including social support, social roles, loneliness, social anxiety, and social network characteristics, relates to physical activity, sedentary time, and quality…
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT07259304
- Testing
- Medical Device Usage and Evaluation, Quality-of-Life Assessment, Survey Administration
- Where
- 3 sites in United States
- Volunteers
- 173 people
- Sponsor
- University of Southern California
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Schizophrenia, Schizoaffective Disorder
Brain Health and Exercise in Schizophrenia
To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Poor Memory
- Trial name
- PEHP (NCT01392885)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BC Mental Health and Addictions Research Institute
Cardiology, Psychiatry
Effects of Aerobic Exercise on Cognition,Cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients
The aim of this study is to develop exercise prescription of TBI patients and then to evaluate the effectiveness of programmed aerobic walking exercise to improve cognitive performance, depression relief, motivation, symptom…
- Trial name
- NCT04243226
- Testing
- telehealth-based aerobic walking exercise
- Where
- Taiwan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Parkinson Disease
Exercise Adherence and Optimal Nutrition Post Rehabilitation Among People With Parkinson's Disease
A randomized, controlled trial to evaluate the effect of six months digital follow-up, after a stay at a rehabilitation center, on functional and nutritional status in people with Parkinson Disease.
- Trial name
- mHEXANUT (NCT04945876)
- Testing
- Digital follow-up
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo Metropolitan University
Hydration Status
Hydrate Heroes for Improving Brain Function & Mood
The primary goal of this 12-week randomized controlled study is to evaluate whether daily use of Hydrate Heroes results in measurable improvements in brain activity, mental health, and performance on cognitive tasks.
- Trial name
- NCT07241260
- Testing
- Hydrate Heroes (6 packets), Hydrate Heroes (3 packets)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Brain Concussion
Mobile Subthreshold Exercise Program for Concussion
Non-randomized pilot intervention using mobile-administered sub-threshold exercise to treat youth with prolonged symptoms of concussion.
- Trial name
- M-STEP (NCT03691363)
- Testing
- M-STEP
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Seattle Children's Hospital
Sedentary Lifestyle
Effects of a Bicycling Intervention on Cognitive Skills and Cardiovascular Health
Although exercise is known to delay cognitive decline and decrease our risk of Alzheimer's Disease, there is a lack of understanding of how exercise protects the aging brain.
- Trial name
- BIKE (NCT02453178)
- Testing
- Cycling
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Iowa