Clinical trials: Brain Injuries
Infarction, Stroke
Polymorphisms in the Vitamin D System and Health
Polymorphisms in the vitamin D system appear to affect the serum 25(OH)D levels. If so one would expect these polymorphisms to be associated with vitamin D related conditions and diseases, which will be tested in the present…
- Conditions
- Infarction, Stroke, Diabetes, Fracture
- Trial name
- NCT01395303
- Where
- Norway
- Volunteers
- 9,700 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Traumatic Brain Injury, Hypopituitarism
Posttraumatic Hypopituitarism - Incidence, Predictors and Test Validity
The purpose of the study is to estimate the incidence of posttraumatic hypopituitarism, and to identify predisposing factors in order to establish a rational responsible socioeconomic screening program.
- Trial name
- NCT01028742
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cerebral Palsy, Dyspraxia
Immersive Virtual Environments and Wearable Haptic Devices in Rehabilitation of Children With Neuromotor Impairments
The investigators proposed a controlled, single-blind, unicentric, crossover, randomized, clinical trial to test the effects of immersive virtual environments and wearable haptic devices in the rehabilitation of children with…
- Trial name
- SERIOUSGAME (NCT03353623)
- Testing
- Serious Game, Conventional Therapy
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Stroke
Moving a Paralyzed Hand Through Use of a Brain-Computer Interface
This study will gain information on methods of control of a prosthetic arm in stroke patients or traumatic brain inury patients through a technique called "brain-computer interface" (BCI).
- Trial name
- NCT00242242
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Traumatic Brain Injury
PC-Based Cognitive Rehabilitation for Traumatic Brain Injury (TBI)
The investigators evaluated whether it was possible to improve the measurement of memory, attention, and executive function in patients who have suffered traumatic brain injury through the use of computer-based testing.
- Trial name
- NCT00927576
- Testing
- Digit span testing, Spatial span testing, Finger tapping
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorder, Traumatic Brain Injury
Non-invasive Nerve Stimulation for PTSD and Sleep
In this study, our objective is to determine the effect of two different nerve stimulation types in changing sleep architecture.
- Trial name
- NCT03170440
- Testing
- Transcutaneous nerve stimulation location 1
- Where
- 3 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- University of Florida
Emotions, Memory Deficits
Brain Response to Treatment for Pediatric PTSD
This study will examine how brain activation changes as a result of behavioral treatment for posttraumatic stress disorder (PTSD) in adolescents.
- Conditions
- Emotions, Memory Deficits, Post-traumatic Syndrome
- Trial name
- NCT01806701
- Testing
- Trauma-focused cognitive behavioral therapy
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Stanford University
Acquired Brain Injury
Comparison of Two Interventions for Caregivers of Patients With Acquired Brain Injury
The goal of this clinical trial is to compare effectiveness of two interventions for family caregivers of patients with acquired brain injury who are transitioning home after inpatient rehabilitation.
- Trial name
- NCT06126549
- Testing
- Building Better Caregivers, Problem Solving Training, Usual Care
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Shepherd Center, Atlanta GA
Cerebral Palsy
Protocol Validation of Dynamometric Measurement of Passive Inter-segmental Stiffness and Spasticity in Children With Cerebral Palsy
Cerebral palsy (CP) refers to a group of movement and posture disorders responsible for activity limitation due to brain damage that occurs during fetal development or during the first year of a child's life.
- Trial name
- NCT04596852
- Testing
- Assessment of the reliability of a protocol characterizing intersegmental hyper-resistance to passive stretch
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Fondation Ellen Poidatz
Spinal Cord Injuries, Bladder, Neurogenic
Functional Changes in the Brain After Tibial Nerve Stimulation: a Pilot Study
The lower urinary tract is innervated by the autonomous (sympathetic, parasympathetic) and the somatic nervous system. Afferent information from the lower urinary tract (LUT) (e.g.
- Trial name
- NCT03908047
- Testing
- magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Vascular System Injuries, Concussion, Brain
Sildenafil Treatment for Mild TBI
About 300,000 people are hospitalized for traumatic brain injury (TBI) each year. After TBI, secondary brain injury escalates due in part to heightened levels of oxidant injury, inflammation, and vascular injury.
- Conditions
- Vascular System Injuries, Concussion, Brain, Post-Concussion Syndrome
- Trial name
- NCT03598140
- Testing
- Sildenafil Citrate
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Spinal Cord Injury, ALS (Amyotrophic Lateral Sclerosis)
Clinical Outcome Assessment for AT & BCI
Many individuals with severe motor impairments rely on Assistive Technologies (ATs) or Brain-Computer Interfaces (BCIs) to interact with digital devices such as their computers.
- Trial name
- NCT07407725
- Testing
- Eye Tracker, Mouth Operated Joystick, Non-invasive electroencephalogram (EEG) Headset
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Concussion, Mild
The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health
The purpose of this pilot study is to better understand the effects of chronic cannabis (THC) use on the neural responses to subconcussive head impacts, as a form of repetitive soccer headings.
- Trial name
- NCT04641832
- Testing
- Soccer heading
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Indiana University
Brain Injuries
The Use of Implementation Intentions to Increase the Appointment Attendance of OEF/OIF Veterans
The purpose of the current pilot study will be to utilize implementation intentions to increase patient compliance with appointment attendance.
- Trial name
- NCT01649934
- Testing
- Implementation Intention, Contact Clinic
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- VA Connecticut Healthcare System
Brain Injuries, Traumatic
Biochemical Diagnostics of Mild Traumatic Brain Injury (TBI) and Concussion in Children and Adolescents
The study will enroll children and adolescents (0 - 17 years) suspected of having concussion or mild traumatic brain injury (TBI).
- Trial name
- NCT04288167
- Testing
- Sample collection
- Where
- Finland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Medicortex Finland Oy
CSF Leak, CSF Pressure Increased
Conservative vs Interventional Management of Postsurgical CSF Pseudomeningocele
Dear Sir or Madam, You have been invited to participate in a clinical study whose aim is to compare the effectiveness of two different approaches to the treatment of cerebrospinal fluid (CSF) pseudomeningocele - conservative…
- Conditions
- CSF Leak, CSF Pressure Increased, CSF Circulation Disorder, Puncture
- Trial name
- PSEUDO (NCT07614399)
- Testing
- Lumbar Drainage, Pseudomeningocele Puncture, Puncture with Fibrin Glue Application
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Concussion
Pathology in the Brain After mTBI - A Multimodal MRI Study
The purpose is to use Diffusion Kurtosis Imaging (DKI), Diffusion Tensor Imaging (DTI) and resting state functional MRI to examine tissue damage in the brains of people who have had a concussion, both acute and 3 months after the…
- Trial name
- NCT01936792
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cerebral Palsy
Compliance of Parents of Children With Cerebral Palsy to Home Program Questionnaire
This study aims to evaluate the psychometric properties of the Compliance of Parents of Children with Cerebral Palsy to Home Program Assesment Questionnaire (CPHP-Q), a caregiver-report for adherence and frequency of home program…
- Trial name
- CoPoCPHP (NCT04813393)
- Testing
- Questionnaire Development
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Executive Functions in Cerebral Palsy
Personalized Innovative Intervention Pathways to Promote EF in Children With CP
Cerebral palsy (CP) is an umbrella term, covering a group of disorders of movement and posture. It is now accepted that CP represents much more than a disorder of movements considering the frequent association with a broad range…
- Trial name
- NCT06288971
- Testing
- Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities, Tele-rehabilitation of EF and specific cognitive processes underlying academic skills, Game-based tools for the rehabilitation of EF and motor planning
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Cerebral Palsy (CP), Typically Developing Children
Interaction Between Spasticity and the Initial Response After Balance Perturbations in Children With Spastic Cerebral Palsy
The aim of this study was to investigate the link between spasticity and the initial response after standing balance perturbations in children with spastic cerebral palsy.
- Trial name
- NCT07616193
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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