Clinical trials: Brain Injuries
Brain Injuries
Examination of Virtual Supermarket (Vmall) as an Assessment of Executive Functions in Children and Adolescents With Acquired Brain Injury
The purpose of this research is to find whether or not there are differences in the executive functions during "shopping" in a "virtual mall", between children with Acquired Brain Injury (ABI) vs healthy children.
- Trial name
- NCT00425958
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Traumatic Brain Injury
Developing Process-Specific Verbal Memory Interventions for Veterans With Tramatic Brain Injury (TBI)
Blast-related and blunt traumatic brain injury is a key priority area of Rehabilitation Research \& Development (RR\&D) and represents a critically important public health problem facing the Veteran population.
- Trial name
- DPSVM (NCT02310633)
- Testing
- Memory Strategy Training, Errorless Learning, Retrieval Practice
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Brain Injuries
Improvised Explosive Device (IED) Level Blasting of Human Blood With Slosh Prevention
To monitor changes in indicators of red cell damage such as extracellular hemoglobin, potassium (K-ABL), and lactate dehydrogenase (LD) post blast exposure.
- Trial name
- NCT03018548
- Testing
- blood draw
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cerebral Palsy
Quantifying Energetic Demands of Walking for People With Cerebral Palsy
The purpose of this study is to examine the underlying mechanisms that contribute to high energy costs for people with cerebral palsy (CP) as they walk.
- Trial name
- NCT04303078
- Testing
- Varying levels of harness support during walking
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Trauma, Brain
The Role of Hypoxia on Subconcussive Head Impacts
The purpose of this study is to examine the combined effects of hypoxia and a short bout of subconcussive head impacts on neurocognitive and ocular-motor function and plasma expression of brain-derived blood biomarkers.
- Trial name
- NCT04624152
- Testing
- Soccer heading
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Indiana University
Stroke, Shoulder Impingement Syndrome
An Innovative Proprioceptive Instrument for Upper Extremities
This study aimed to develop and validate an innovative proprioceptive assessment instrument for the upper extremities, the PropArm-PosiMoF (PropArm). This observational study was conducted in three stages.
- Conditions
- Stroke, Shoulder Impingement Syndrome, Diabetes (DM), Healthy Young Adults
- Trial name
- NCT07779928
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Diplegia, Spastic
Eye-Hand Coordination in Children With Spastic Diplegia
This study will examine how the brain controls eye-hand coordination (visuomotor skills) in children with spastic diplegia and will determine whether impairment of this skill is related to the learning difficulties in school that…
- Trial name
- NCT00024791
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Traumatic Brain Injury, Controls
Traumatic Brain Injury Feasibility Study (EPIC-011)
The purpose of this research study is to evaluate whether data made by the ClearView System can be used to detect whether someone has a traumatic brain injury and how severe the injury is.
- Trial name
- TBI (NCT02471625)
- Testing
- ClearView Scanning
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Spinal Cord Injury
Cardiovascular, Cerebrovascular, and Cognitive Function in Spinal Cord Injury
Increased life expectancy in individuals with spinal cord injury (SCI) present clinicians with the challenge of managing the secondary complications of SCI with the chronic diseases common in an aging population.
- Trial name
- NCT02122991
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Traumatic Brain Injuries
Validation and Standardisation of a "Neuralix" Digital Ecological Battery
The management of head trauma patients requires the assessment of cognitive disorders using standardized neuropsychological tests and questionnaires.
- Trial name
- VANOLIX (NCT06830291)
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Traumatic Brain Injury, Coping Skills
Brain Injury Coping Skills - Telemedicine: Phase II
For phase II, the objective is to compare the effectiveness of BICS-T with the well-established BICS in-person group. Information gained from phase I (the feasibility study) was used to make necessary changes to the BICS-T…
- Conditions
- Traumatic Brain Injury, Coping Skills, Caregivers
- Trial name
- BICS-T-2 (NCT04386655)
- Testing
- Brain Injur Coping Skills - Telemedicine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Devan Parrott
Cerebral Palsy
Motor Learning in People With Cerebral Palsy by Using Virtual Reality.
Cerebral Palsy (CP) is a group of permanent disorders that affect movement and posture due to a non-progressive lesion in the immature brain occurring in fetal brain development or in infancy.
- Trial name
- NCT03348943
- Testing
- Right hemiparesis, right upper limb., Right hemiparesis, left upper limb, Left hemiparesis, left upper limb
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Care Partners of Patients With Traumatic Brain Injury (TBI)
Problem Solving Training for Care Partners of Adults With Traumatic Brain Injury
Importance: The chronic consequences of TBI are established, but ongoing support for adults with TBI living in the community is limited.
- Trial name
- CP-PST (NCT03739450)
- Testing
- Problem Solving Training (PST), Education
- Where
- 4 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Traumatic Brain Injury, Cerebral Infarction
Characteristics of Blood- Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood- brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and…
- Conditions
- Traumatic Brain Injury, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00419874
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Cerebral Palsy, Children
Cerebral Palsy and the Study of Brain Activity During Motor Tasks
Background: Two ways to study the brain while people are moving are near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses light to look at blood flow in the brain when it is active.
- Trial name
- NCT01829724
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Systemic Lupus Erythematosus
fMRI Study of Early Brain Injury in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs and systems. The central nervous system is one of the most commonly involved parts, and the involvement of the nervous system is called…
- Trial name
- NCT06226324
- Testing
- neuropsychological test
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Inner Mongolia Medical University
Mental Retardation, Developmental Disabilities
Healthy Lifestyles for People With Intellectual Disabilities
Relatively few health promotion and disease prevention programs have included or targeted people with disabilities, and even fewer have focused on individuals with intellectual disabilities.
- Conditions
- Mental Retardation, Developmental Disabilities, Intellectual Disabilities
- Trial name
- HLID (NCT00597948)
- Testing
- Healthy Lifestyles Curriculum
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Spinal Cord Injuries, Neuropathic Pain
Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury
Many adults with spinal cord injury (SCI) suffer from long-term debilitating neuropathic pain. Available treatments, including opioids, are ineffective at eliminating this pain.
- Trial name
- NCT04706208
- Testing
- Cognitive Multisensory Therapy, Usual Care, Clinical Assessment
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Brain Injuries, Traumatic, Post-traumatic Stress Disorder
Morning Bright Light to Improve Sleep Quality in Veterans
One of the principal complicating factors associated with traumatic brain injury (TBI) is sleep-wake disturbances (e.g., insomnia, excessive daytime sleepiness, and circadian rhythm sleep disorders).
- Trial name
- NCT03578003
- Testing
- Morning Bright Light Therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Portland VA Medical Center
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