Clinical trials: Brain Injuries
Traumatic Brain Injury
Traumatic Brain Injury Biological Diagnosis Via High Definition Tractography Asymmetry Screening
The primary purpose of this study is to validate the High Definition Fiber Tracking (HDFT/HDFTAS) technology, so that faster, more reliable diagnosis can be implemented in Traumatic Brain Injury (TBI).
- Trial name
- NCT02728960
- Testing
- MRI of the Brain (No Contrast) Scan
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cerebral Palsy, Gait Disorders in Children
Validity and Reliability of the WAL-K Test
Adapting the environment in which a child with Cerebral Palsy lives or adapting himself according to the environment facilitates independence in daily life activities.
- Trial name
- NCT05309096
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Pineal Gland Disorder, Corpus Callosum Atrophy
Corpus Callosum Size in Patients With Pineal Cyst
This study aims to determine size of corpus callosum on midsagittal MR scan in patients with a pineal cyst and to compare it with the control group without a pineal cyst.
- Conditions
- Pineal Gland Disorder, Corpus Callosum Atrophy, Cerebral Palsy
- Trial name
- NCT03183427
- Testing
- MR of the brain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague
Cerebral Palsy (CP), Typically Developing Children
The Effect of Perturbation Training on Reactive Balance in Children With Cerebral Palsy
The aim of this project was to evaluate whether perturbation training influences reflex modulation in children with spastic CP and whether changed reflex modulation leads to improved reactive balance and walking.
- Trial name
- NCT07818928
- Testing
- Balance training on a moving platform
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
SCI - Spinal Cord Injury
Gut-Brain Neural Coupling in Spinal Cord Injury
The purpose of this research is to determine the effects of food on brain and stomach activity in persons with and without spinal cord injury (SCI).
- Trial name
- NCT07052344
- Testing
- Preload condition, Ad-libitum control condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Brain Injury, Cerebral Palsy
The Connection Between Gait Variability Parameters and Balance Performance in Children With Physical Disability
The purpose of this study is to explore the connection between gait variability parameters and balance performance in children with physical disability
- Trial name
- NCT00338858
- Testing
- walking and balance performance evaluation, muscle strength, walking and balance performance
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Brain Concussion, Post-Concussion Syndrome
Investigating Novel Treatments for Concussion: Impact of Compression Vest on Rehabilitation Outcomes
The purpose of this investigation is to determine the effect of a weighted compression vest in addition to usual medical care and exercise rehabilitation on cardiovascular, neurocognitive, balance and anxiety measures in…
- Trial name
- NCT02362347
- Testing
- London Health Sciences Centre - Compression Vest, exercise
- Where
- 2 sites in Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Brain Injuries, Cerebrovascular Disorders
Measuring Blood Flow Characteristics Using Dynamic Contrast Enhanced Magnetic Resonance Imaging
Dynamic contrast-enhanced (DCE) MRI gives quantitative and semi-quantitative information about the integrity of the vascular system and can be used to quantify blood-brain barrier (BBB) integrity.
- Trial name
- NCT02702635
- Testing
- DCE MRI of the brain
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Traumatic Brain Injury
Improving Anticipatory and Compensatory Postural Responses to Avoid Falls After TBI
The purpose of this study is to assess a balance training program to see if it can be helpful to avoid falls in people who have had traumatic brain injuries (TBIs).
- Trial name
- NCT05268484
- Testing
- Perturbation-based Training with visual cues using Neurocom
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Premature Birth, Cerebral Palsy
Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants
This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied.
- Conditions
- Premature Birth, Cerebral Palsy, Neurodevelopmental Disorders, Brain Injuries
- Trial name
- BAMBI (NCT06111898)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Caregiver Burden, Caregiver Stress Syndrome
Traumatic Brain Injury and Alzheimer's Disease/Related Dementias Caregiver Support Intervention
The TBI-AD/ADRD Caregiver Support Intervention (TACSI) incorporates psychosocial and psychoeducational approaches with the objective of: a) identifying stressors associated with caregiving for family members who have the dual…
- Conditions
- Caregiver Burden, Caregiver Stress Syndrome, Caregiver Burnout
- Trial name
- TACSI (NCT05465109)
- Testing
- TBI-AD/ADRD Caregiver Support Intervention (TACSI)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Concussion, Brain
Neurocognitive Dysfunction After Anesthesia in Patients With Recent Concussion
Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.
- Trial name
- NCT03952208
- Testing
- Neurocognitive Testing
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Brain Injury Traumatic Mild
Spotting and Managing Adult Repeated Traumas in the Brain
Emerging evidence suggests that concussions (a type of mild traumatic brain injury; mTBIs) may cause chronic neurological disturbances with effects lasting beyond 20 years, changing brain structure and nearly doubling the risks…
- Trial name
- SMARTBRAIN (NCT07025317)
- Testing
- Perceptual-cognitive
- Where
- 3 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Post-stroke Dementia, Vascular Mild Cognitive Impairment
The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke
Stroke can lead to signficiant neurological deficits, and about one-third of stroke patients will be diagnosed of vascular mild cognitive impairment or post-stroke dementia.
- Trial name
- NCT04588649
- Testing
- THK-5351, AV-45
- Where
- Taiwan
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
To Compare the Effectiveness of Hydrotherapy Versus Aerobic Exercise on Pulmonary Function in Hemiplegic Children With Cerebral Palsy
Effect of Hydrotherapy Versus Aerobic Exercise on Pulmonary Function on Hemiplegic Cerebral Palsied Children
Cerebral palsy (CP) is the most common motor disability in childhood. Respiratory muscle weakness and a low upper to lower chest diameter ratio are common respiratory dysfunction manifestations in those children which negatively…
- Trial name
- NCT06086678
- Testing
- Conventional physical therapy, Hydrotherapy, Aerobic exercise
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- South Valley University
Brain Concussion
Mild Traumatic Brain Injury Discrimination
Evaluation of the utility of a multi-modal assessment tool in distinguishing between individuals with and without a history of mild traumatic brain injury.
- Trial name
- MTBID (NCT02453958)
- Testing
- Multi-modal assessment system
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Empirical Technologies Corporation
Ambulances, Traumatic Brain Injury
Differences in Mortality and Morbidity in Patients Suffering a Time-critical Condition Between GEMS and HEMS
Introduction: Patients suffering a time-critical medical condition require rapid prehospital assessment and treatment and most often quick transportation to definitive care. This can be decisive for patient outcome.
- Conditions
- Ambulances, Traumatic Brain Injury, Acute Myocardial Infarction
- Trial name
- NCT03940443
- Where
- Sweden
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Acquired Brain Injury
Rewards Sensitivity After Brain Injury
A study measuring rewards sensitivity in individuals with acquired brain injury at an acute rehabilitation level.
- Trial name
- NCT06510023
- Testing
- Type of reward presented
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Preterm, Patent Ductus Arteriosus
NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
Non-invasive tools for monitoring of course of disease are important and necessary in the treatment of pre-term/premature infants and sick neonates.
- Conditions
- Preterm, Patent Ductus Arteriosus, Sepsis, Asphyxia
- Trial name
- CE-NeoDoppler (NCT06646250)
- Testing
- NeoDoppler - CE certified
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Brain Injuries
The Value of Multimodal MR Imaging in Cognitive Assessment of Patients With Moderate Traumatic Brain Injury
The goal of this observational study is to learn about in The value of multimodal MR Imaging in cognitive assessment of patients with moderate traumatic brain injury.
- Trial name
- NCT06099210
- Testing
- Glasgow coma scale
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
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